Dr. rer. nat. Katharina Hillerer

Research Institute for Farm Animal Biology (FBN)
Working Group Psychophysiology
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Research interests

My research investigates how chronic stress and/or stressful environmental conditions may affect the neuroendocrinology and plasticity of the brain during sensitive time windows like pregnancy, lactation and early development. I am mainly interested in neuronal parameters like adult hippocampal neurogenesis and dendritic plasticity in different stress-relevant brain regions. Moreover, I focus on neuroendocrine parameters that might correlate with the neuronal parameters mentioned above and their potential use as markers of stress and welfare in modern livestock farming. Furthermore, I aim to investigate if preventive application of probiotics may buffer neuronal and neuroendocrine stress effects.

Main research topics:

  • Alterations of adult hippocampal neurogenesis and dendritic plasticity under stressful conditions
  • Neuroendocrine parameters of stress and welfare
  • Microbiota-Gut-Brain-Axis in the context of animal welfare

Curriculum Vitae

  • Since 09/2023: Research Scientist, KF4B Psychophysiology, Research Institute for Farm Animal Biology(FBN), Dummerstorf, Germany
  • 11/2013-07/2023: Head of the Perinatal Research Laboratory at the University Clinic Institute of Gynecology and Obstetrics Salzburg (PMU), Clinical Research Center Salzburg (CRCS), Salzburg, Austria
  • 05/2012-10/2013: Postdoctoral Research Fellow at the Douglas Mental Health University Institute, McGill University, Montréal, Canada
  • 01/2008-03/2012: PhD, Department of Neurobiology and Animal Physiology (Prof. Dr. Inga Neumann), University of Regensburg, Germany
  • 03/2007-12/2007: Diploma (Biology/Neurobiology), Department of Neurobiology and Animal Physiology (Prof. Dr. Inga Neumann), University of Regensburg, Germany

Publications

Hillerer, K. M.; Gimsa, U. (2024):
Adult neurogenesis and the microbiota-gut-brain axis in farm animals: underestimated and understudied parameters for improving welfare in livestock farming
Frontiers in Neuroscience 18: 1493605, 1-24
https://doi.org/10.3389/fnins.2024.1493605
Pletzer, B.; Winkler-Crepaz, K.; Hillerer, K.M. (2023):
Progesterone and contraceptive progestin actions on the brain: A systematic review of animal studies and comparison to human neuroimaging studies
Frontiers in Neuroendocrinology 7:101060
https://doi.org/10.1016/j.yfrne.2023.101060
Fischer, T.; Helmer, H.; Klaritsch, P.; Fazelnia, C.; Bogner, G.; Hillerer, K.M.; Wohlmuth, C.; Jaksch-Bogensperger, H. (2022):
Diagnosis and Therapy of Iron Deficiency Anemia During Pregnancy: Recommendation of the Austrian Society for Gynecology and Obstetrics (OEGGG)
Geburtshilfe und Frauenheilkunde 82 (4): 392-399
https://doi.org/10.1055/a-1710-3387
Hillerer, K.M.; Slattery, D.A.; Pletzer, B. (2019):
Neurobiological mechanisms underlying sex-related differences in stress-related disorders: Effects of neuroactive steroids on the hippocampus
Front Neuroendocrinol 55:100796
https://doi.org/10.1016/j.yfrne.2019.100796
Hillerer, K.M.; Woodside, B.; Parkinson, E.; Long, H.; Verlezza, S.; Walker, C.D. (2018):
Gating of the neuroendocrine stress responses by stressor salience in early lactating female rats is independent of infralimbic cortex activation and plasticity
Stress 21(3):217-228
https://doi.org/10.1080/10253890.2018.1434618
Sharp, A.; Chappell, L.C.; Dekker, G.; Pelletier, S.; Garnier, Y.; Zeren, O.; Hillerer, K.M.; Fischer, T.; Seed, P.T.; Turner, M.; Shennan, A.H.; Alfirevic, Z. (2018):
Placental Growth Factor informed management of suspected pre-eclampsia or fetal growth restriction: The MAPPLE cohort study
Pregnancy Hypertens 14:228-233
https://doi.org/10.1016/j.preghy.2018.03.013
Slattery, D.A.; Hillerer, K.M. (2016):
The maternal brain under stress: Consequences for adaptive peripartum plasticity and its potential functional implications
Front Neuroendocrinol
https://doi.org/10.1016/j.yfrne.2016.01.004
Hillerer, K.M.; Jacobs, V.R.; Aigner, L.; Fischer, T. (2015):
Changes in maternal cognition after pregnancies with preeclampsia
Pregnancy Hypertension 5(1):128
https://doi.org/10.1016/j.preghy.2014.10.260
Yong Ping, E.; Laplante, D.P.; Elgbeili, G.; Hillerer, K.M.; Brunet, A.; O'Hara, M.W.; King, S. (2015):
Prenatal maternal stress predicts stress reactivity at 2½ years of age: the Iowa Flood Study
Psychoneuroendocrinology 56:62-78
https://doi.org/10.1016/j.psyneuen.2015.02.015
Hillerer, K.M.; Neumann, I.D.; Couillard-Despres, S.; Aigner, L.; Slattery D.A. (2014):
Lactation-induced reduction in hippocampal neurogenesis is reversed by repeated stress exposure
Hippocampus 2014
https://doi.org/10.1002/hipo.22258
Hillerer, K.M.; Jacobs, V.R.; Fischer,T.; Aigner, L. (2014):
The maternal brain: An organ with peripartal plasticity
Neural Plasticity 2014
https://doi.org/10.1155/2014/574159
Hillerer, K.M.; Neumann, I.D.; Couillard-Despres, S.; Aigner, L.; Slattery, D.A. (2013):
Sex-dependent regulation of hippocampal neurogenesis under basal and chronic stress conditions in rats
Hippocampus 2013
https://doi.org/10.1002/hipo.22107
Hillerer, K.M.; Neumann, I.D.; Slattery, D.A. (2012):
From stress to postpartum mood and anxiety disorders: How chronic peripartum stress can impair maternal adaptations
Invited Review to Neuroendocrinology 95(1):22-38
https://doi.org/10.1159/000330445
Hillerer, K.M.; Reber, S.; Neumann, I.D.; Slattery, D.A. (2011):
Exposure to chronic pregnancy stress reverses peripartum associated adaptations: implications for postpartum anxiety and mood disorders
Endocrinology 152(10):3930-40
https://doi.org/10.1210/en.2011-1091