Dr. rer. nat. Juliane Günther
Research Institute for Farm Animal Biology (FBN)
working group Glycoimmunology
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
working group Glycoimmunology
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Research interests
- Molecular Biology
- Infection Biology, Cell Biology
- Immunology
- Epigenetics
- Cell Signalling
Curriculum Vitae
- since 2013: Junior Group Leader, Genome Physiology Unit, Leibniz Institute for Farm Animal Biology (FBN)
- 2006-2013: Postdoctoral Research Fellow, Group Gene Analysis, Leibniz Institute for Farm Animal Biology (FBN)
- 2005: Ph.D. (Dr. rer. nat.) at the Friedrich Schiller University of Jena
- 2002-2005: Ph.D. student, Leibniz Institute for Natural Product Research and Infection Biology (Hans-Knöll-Institute), Jena, Germany
- 2001: Diploma (Biology) at the Friedrich Schiller University of Jena
- 1995-2001: Studies in Biological Sciences, Friedrich Schiller University of Jena, Germany
Teaching
- since 2011: „Diversity and Evolution“ (MSc), Faculty of Mathematics and Natural Sciences, University of Rostock, Germany
Publications
Günther, J.; Schuler, G.; Teppa, E.; Fürbass, R. (2024):
Charged Amino Acids in the Transmembrane Helix Strongly Affect the Enzyme Activity of Aromatase
International Journal of Molecular Sciences 25 (3): 1440, 1-13
https://doi.org/10.3390/ijms25031440
Hinterseher, J.; Günther, J.; Zlatina, K.; Isernhagen, L.; Viergutz, T.; Wirthgen, E.; Höflich, A.; Vernunft, A.; Galuska, S. P. (2023):
Milk Polysialic Acid Levels Rapidly Decrease in Line with the N-Acetylneuraminic Acid Concentrations during Early Lactation in Dairy Cows. BIOLOGY-BASEL 12 (1): 5, 1-12
Sebastian Peter Galuska,
Christina Galuska,
Juliane Günther,
Andreas Höflich,
Andreas Vernunft,
Kristina Zlatina,
Lisa Isernhagen
Günther, J.; Galuska, S. P. (2023):
A brief history of galectin evolution. Front Immunol 14: 11147356, 1-13
Magray, A. R.; Martorell Ribera, J.; Isernhagen, L.; Galuska, S. P.; Günther, J.; Verleih, M.; Viergutz, T.; Brunner, R. M.; Ganai, B.; Ahmad, F.; Zlatina, K.; Rebl, A. (2022):
Evaluation of blood cell viability rate, gene expression, and O-GlcNAcylation profiles as indicative signatures for fungal stimulation of salmonid cell models. MOL IMMUNOL 142: 120-129
Sebastian Peter Galuska,
Christina Galuska,
Juliane Günther,
Kristina Zlatina,
Marieke Verleih,
Lisa Isernhagen
https://doi.org/10.1016/j.molimm.2021.12.019
Revskij, D.; Haubold, S. S.; Plinski, C.; Viergutz, T.; Tuchscherer, A.; Kröger-Koch, C.; Albrecht, E.; Günther, J.; Tröscher, A.; Hammon, H. M.; Schuberth, H.-J.; Mielenz, M. (2022):
Cellular detection of the chemokine receptor CXCR4 in bovine mammary glands and its distribution and regulation on bovine leukocytes. J Dairy Sci 105 (1): 866-876
https://doi.org/10.3168/jds.2021-20799
Hachem, N. E.; Humpfle, L.; Simon, P.; Kaese, M.; Weinhold, B.; Günther, J.; Galuska, S. P.; Middendorff, R. (2021):
The Loss of Polysialic Acid Impairs the Contractile Phenotype of Peritubular Smooth Muscle Cells in the Postnatal Testis. Cells-Basel 10 (6): 1347, 1-12
https://doi.org/10.3390/cells10061347
Günther, J.; Fallarino, F.; Fuchs, D.; Wirthgen, E. (2020):
Editorial: Immunomodulatory roles of tryptophan metabolites in inflammation and cancer. Front Immunol 11: 1497,1-3
https://doi.org/10.3389/fimmu.2020.01497
Knaust, J.; Weikard, R.; Albrecht, E.; Brunner, R. M.; Günther, J.; Kühn, C. (2020):
Indication of premelanosome protein (PMEL) expression outside of pigmented bovine skin suggests functions beyond eumelanogenesis. Genes-Basel 11 (7): 788,1-13
https://doi.org/10.3390/genes11070788
Polei, M.; Günther, J.; Koczan, D.; Fürbaß, R. (2020):
Gene expression profiles of bovine uninucleate trophoblast cells and trophoblast giant cells: a data note. BMC Res Notes 13: 115, 1-3
https://doi.org//10.1186/s13104-020-04964-z
Polei, M.; Günther, J.; Koczan, D.; Fürbaß, R. (2020):
Trophoblast cell differentiation in the bovine placenta: Differentially expressed genes between uninucleate trophoblast cells and trophoblast giant cells are involved in the composition and remodeling of the extracellular matrix and O-glycan biosynthesis. BMC Mol Cell Biol 21: 1, 1-12
https://doi.org/10.1186/s12860-020-0246-8
Günther, J.; Däbritz, J.; Wirthgen, E. (2019):
Limitations and off-target effects of tryptophan-related IDO inhibitors in cancer treatment. Front Immunol 10: 1801, 1-8
https://doi.org/10.3389/fimmu.2019.01801
Brodhagen, J.; Weikard, R.; Thom, U.; Heimes, A.; Günther, J.; Hadlich, F.; Zerbe, H.; Petzl, W.; Meyerholz, M. M.; Hoedemaker, M.; Schubert, H-J; Engelmann, S.; Kühn, C. (2019):
Development and evaluation of a milk protein transcript depletion method for differential transcriptome analysis in mammary gland tissue. BMC Genomics 20 (1): 400, 1-19
https://doi.org/10.1186/s12864-019-5781-3
Günther, J.; Seyfert, H.M. (2018):
The first line of defence: insights into mechanisms and relevance of phagocytosis in epithelial cells. Semin Immunopathol 40 (6): 555-565
https://doi.org/10.1007/s00281-018-0701-1
Wirthgen, E.; Otten, W.; Tuchscherer, M.; Tuchscherer, A.; Domanska, G.; Brenmoehl, J.; Günther, J.; Ohde, D.; Weitschies, W.; Seidlitz, A.; Scheuch, E.; Kanitz, E. (2018):
Effects of 1-Methyltryptophan on immune responses and the kynurenine pathway after lipopolysaccharide challenge in pigs. Int J Mol Sci 19 (10): 3009, 1-23
https://doi.org/10.3390/ijms19103009
Petzl, W.; Zerbe, H.; Günther, J.; Seyfert, H.-M.; Hussen, J.; Schuberth, H.-J. (2018):
Pathogen-specific responses in the bovine udder: Models and immunoprophylactic concepts. Res Vet Sci 116: 55-61
https://doi.org/10.1016/j.rvsc.2017.12.012
Wirthgen, E.; Hoeflich, A.; Rebl, A.; Günther, J. (2017):
Kynurenic acid: The Janus-faced role of an immunomodulatory tryptophan metabolite and its link to pathological conditions. Front Immunol 8: 1957, 1-13
https://dx.doi.org/10.3389/fimmu.2017.01957
Günther, J.; Petzl, W.; Bauer, I.; Ponsuksili, S.; Zerbe, H.; Schuberth, H.-J.; Brunner, R. M.; Seyfert, H.-M. (2017):
Differentiating Staphylococcus aureus from Escherichia coli mastitis: S. aureus triggers unbalanced immune-dampening and host cell invasion immediately after udder infection. Sci Rep-UK 7: 4811,1-14
https://dx.doi.org/10.1038/s41598-017-05107-4
Günther, J.; Petzl, W.; Zerbe, H.; Schuberth, H.-J.; Seyfert, H.-M. (2017):
TLR ligands, but not modulators of histone modifiers, can induce the complex immune response pattern of endotoxin tolerance in mammary epithelial cells. Innate Immun-London 23 (2): 155-164
https://dx.doi.org/10.1177/1753425916681076
Petzl, W.; Günther, J.; Mühlbauer, I.C.; Seyfert, H.-M.; Schuberth, H.-J.; Hussen, J.; Sauter-Louis, C.; Hafner-Marx, A.; Zerbe, H. (2016):
Early transcriptional events in the udder and teat after intramammary Escherichia coli and Staphylococcus aureus challenge. Innate Immun-London 22 (4): 294-304
https://dx.doi.org/10.1177/1753425916640057
Günther, J.; Koy, M.; Berthold, A.; Schuberth, H.-J.; Seyfert, H.-M. (2016):
Comparison of the pathogen species-specific immune response in udder derived cell types and their models. Vet Res 47: 22, 1-11
https://dx.doi.org/10.1186/s13567-016-0307-3