Dr. rer. nat. Julia Brenmoehl
Research Institute for Farm Animal Biology (FBN)
working group Endocrinology of Farm Animals
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
working group Endocrinology of Farm Animals
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Research interests
- Control of fat and energy metabolism, cell signalling
Curriculum Vitae
- 2009: Research Institute for Farm Animal Biology (FBN)
- 2007–2009: University Hospital Jena, Internal Medicine IV, Department for Gastroenterology, Hepatology und Infectiology
- 2005–2007: Graduation (Dr. rer. nat.)
- 2003–2004: Postgraduate studies in subject biology, University Regensburg; qualification receipt for graduation
- 2002–2006: University Hospital Regensburg, Department of Gastroenterology, Endocrinology, Rheumatology, Infectiology, Emergency Medicine
- 2002: University Hospital Rostock, Internal Medicine, Department of Gastroenterology
- 2001–2001: Creatogen AG Augsburg, Department: Vaccines
- 1997–2002: Biotechnology studies, university of applied science Jena
- 1997: Diploma from German secondary school qualifying for university admission or matriculation
Publications
Grube, M.; Brenmoehl, J.; Rogler, G.; Hahn, J.; Herr, W.; Holler, E. (2015):
Donor nucleotide-binding oligomerization-containing protein 2 (NOD2) single nucleotide polymorphism 13 is associated with septic shock after allogeneic stem cell transplantation. Biol Blood Marrow Tr 21 (8): 1399-1404
https://dx.doi.org/10.1016/j.bbmt.2015.05.011
Ohde, D.; Brenmoehl, J.; Walz, C.; Höflich, A. (2015):
Identification and characterization of microRNAs relevant for energy metabolism in Dummerstorf "marathon mice" DUhTP. Schriftenreihe / Leibniz-Institut für Nutztierbiol 24: 33-36"
Reyer, A.; Schindler, N.; Ohde, D.; Walz, C.; Kunze, M.; Tuchscherer, A.; Wirthgen, E.; Brenmoehl, J.; Hoeflich, A. (2015):
The RGD sequence present in IGFBP-2 is required for reduced glucose clearance after oral glucose administration in female transgenic mice. Am J Physiol-Endoc M 309 (4): 409-417
https://dx.doi.org/10.1152/ajpendo.00168.2015
Albrecht, E.; Norheim, F.; Thiede, B.; Holen, T.; Ohashi, T.; Schering, L.; Lee, S.; Brenmoehl, J.; Thomas, S.; Drevon, C. A.; Erickson, H. P.; Maak, S. (2015):
Irisin - a myth rather than an exercise-inducible myokine. Sci Rep-UK 5: 1-10
https://dx.doi.org/10.1038/srep08889
Hoeflich, A.; Wirthgen, E.; David, R.; Classen, C. F.; Spitschak, M.; Brenmoehl, J. (2014):
Control of IGFBP-2 expression by steroids and peptide hormones in vertebrates. Front Endocrinol 5: 43-52
https://dx.doi.org/10.3389/fendo.2014.00043
Brenmoehl, J.; Albrecht, E.; Komolka, K.; Schering, L.; Langhammer, M.; Hoeflich, A.; Maak, S. (2014):
Irisin is elevated in skeletal muscle and serum of mice immediately after acute exercise. Int J Biol Sci 10 (3): 338-349
https://dx.doi.org/10.7150/ijbs.7972
Komolka, K.; Albrecht, E.; Schering, L.; Brenmoehl, J.; Hoeflich, A.; Maak, S. (2014):
Locus characterization and gene expression of bovine FNDC5: is the myokine irisin relevant in cattle?. Plos One 9 (1): 1-11
https://dx.doi.org/10.1371/journal.pone.0088060
Renne, U.; Langhammer, M.; Brenmoehl, J.; Walz, C.; Zeissler, A.; Tuchscherer, A.; Piechotta, M.; Wiesner, R. J.; Bielohuby, M.; Hoeflich, A. (2013):
Lifelong obesity in a polygenic mouse model prevents age- and diet-induced glucose intolerance - obesity is no road to late-onset diabetes in mice. Plos One 8 (11): e79788, 1-8
https://dx.doi.org/10.1371/journal.pone.0079788
Brenmoehl, J.; Walz, C.; Renne, U.; Ponsuksili, S.; Wolf, C.; Langhammer, M.; Schwerin, M.; Hoeflich, A. (2013):
Metabolic adaptations in the liver of born long-distance running mice. Med Sci Sport Exer 45 (5): 841-850
https://dx.doi.org/10.1249/MSS.0b013e31827e0fca
Brenmoehl, J.; Hoeflich, A. (2013):
Dual control of mitochondrial biogenesis by sirtuin 1 and sirtuin 3. Mitochondrion 13 (6): 755-761
https://dx.doi.org/10.1016/j.mito.2013.04.002
Bruns, T.; Peter, J.; Reuken, P. A.; Grabe, D. H.; Schuldes, S. R.; Brenmoehl, J.; Schölmerich, J.; Wiest, R.; Stallmach, A. (2012):
NOD2 gene variants are a risk factor for culture-positive spontaneous bacterial peritonitis and monomicrobial bacterascites in cirrhosis. Liver Int 32 (2): 223-230
https://dx.doi.org/10.1111/j.1478-3231.2011.02561.x
Renne, U.; Sawitzky, M.; Brenmoehl, J.; Bidlingmaier, M.; Bielohuby, M.; Langhammer, M.; Hoeflich, A. (2011):
Funktionale Genomanalyse in Inzuchtlinien und Auszuchtpopulationen: Interaktion von Wachstum und Lebensdauer. In: Biometrische Aspekte der Genomanalyse IV (Biometrie und Medizinische Informatik Greifswalder Seminarberichte , 19) (C. Hemmelmann ..., Hrsg.) Shaker Verlag, Aachen (978-3-8440-0155-6): 99-112
Pinchuk, I.; Beswick, E.; Saada, J.; Boya, G.; Schmitt, A. O.; Raju, G.; Brenmoehl, J.; Rogler, G.; Reyes, V. E.; Powell, D. (2011):
Human colonic myofibroplasts promote expansion of CD4+ CD25high Foxp3+ regulatory T cells. Gastroenterology 140 (7): 2019-2030
https://dx.doi.org/10.1053/j.gastro.2011.02.059
Meier, J. K.-H.; Scharl, M.; Miller, S. N.; Brenmoehl, J.; Hausmann, M.; Kellermeier, S.; Schölmerich, J.; Rogler, G. (2011):
Specific differences in migratory function of myofibroblasts isolated from Crohn's disease fistulae and strictures. Inflamm Bowel Dis 17 (1): 202-212
https://dx.doi.org/10.1002/ibd.21344
Rieder, F.; Georgieva, M.; Schirbel, A.; Artinger, M.; Zügner, A.; Blank, M.; Brenmoehl, J.; Schölmerich, J.; Rogler, G. (2010):
Prostaglandin E2 Inhibits Migration of Colonic Lamina Propria Fibroblasts. Inflamm Bowel Dis 16 (9): 1505-1513
https://dx.doi.org/10.1002/ibd.21255
Kosovac, K.; Brenmoehl, J.; Holler, E.; Falk, W.; Schoelmerich, J.; Hausmann, M.; Rogler, G. (2010):
Association of the NOD2 genotype with bacterial translocation via altered cell-cell contacts in Crohn's disease patients. Inflamm Bowel Dis 16 (8): 1311-1321
https://dx.doi.org/10.1002/ibd.21223
Landfried, K.; Bataille, F.; Rogler, G.; Brenmoehl, J.; Kosovac, K.; Wolff, D.; Hilgendorf, I.; Hahn, J.; Edinger, M.; Hoffmann, P.; Obermeier, J.; Schoelmerich, J.; Andreesen, R.; Holler, E. (2009):
Recipient NOD2/CARD15 status affects cellular infiltrates in human intestinal graft-versus-host disease. Clin Exp Immunol 159 (1): 87-92
https://dx.doi.org/10.1111/j.1365-2249.2009.04049.x
Pohlers, D.; Brenmoehl, J.; Löffler, I.; Müller, M.; Leipner, C.; Schultze-Mosgau, S.; Stallmach, A.; Kinne, R.; Wolf, I (2009):
TGF-β and fibrosis in different organs — molecular pathway imprints. BBA-Mol Basis Dis 1792 (8): 746-756
https://dx.doi.org/10.1016/j.bbadis.2009.06.004
Lang, M.; Schlechtweg, M.; Kellermeier, S.; Brenmoehl, J.; Falk, W.; Schölmerich, J.; Herfarth, H.; Rogler, G.; Hausmann, M. (2009):
Gene expression profiles of mucosal fibroblasts from strictured and nonstrictured areas of patients with Crohn's disease. Inflamm Bowel Dis 15 (2): 212-223
https://dx.doi.org/10.1002/ibd.20735