Dr. rer. nat. Julia Brenmoehl

+49 38208 68-929
Research Institute for Farm Animal Biology (FBN)
Institute of Genome Biology
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Research interests

  • Control of fat and energy metabolism, cell signalling

Curriculum Vitae

  • 2009: Research Institute for Farm Animal Biology (FBN)
  • 2007–2009: University Hospital Jena, Internal Medicine IV, Department for Gastroenterology, Hepatology und Infectiology
  • 2005–2007: Graduation (Dr. rer. nat.)
  • 2003–2004: Postgraduate studies in subject biology, University Regensburg; qualification receipt for graduation
  • 2002–2006: University Hospital Regensburg, Department of Gastroenterology, Endocrinology, Rheumatology, Infectiology, Emergency Medicine
  • 2002: University Hospital Rostock, Internal Medicine, Department of Gastroenterology
  • 2001–2001: Creatogen AG Augsburg, Department: Vaccines
  • 1997–2002: Biotechnology studies, university of applied science Jena
  • 1997: Diploma from German secondary school qualifying for university admission or matriculation


Bruns, T.; Peter, J.; Reuken, P. A.; Grabe, D. H.; Schuldes, S. R.; Brenmoehl, J.; Schölmerich, J.; Wiest, R.; Stallmach, A. (2012):
NOD2 gene variants are a risk factor for culture-positive spontaneous bacterial peritonitis and monomicrobial bacterascites in cirrhosis. Liver Int 32 (2): 223-230
Renne, U.; Sawitzky, M.; Brenmoehl, J.; Bidlingmaier, M.; Bielohuby, M.; Langhammer, M.; Hoeflich, A. (2011):
Funktionale Genomanalyse in Inzuchtlinien und Auszuchtpopulationen: Interaktion von Wachstum und Lebensdauer. In: Biometrische Aspekte der Genomanalyse IV (Biometrie und Medizinische Informatik Greifswalder Seminarberichte , 19) (C. Hemmelmann ..., Hrsg.) Shaker Verlag, Aachen (978-3-8440-0155-6): 99-112
Pinchuk, I.; Beswick, E.; Saada, J.; Boya, G.; Schmitt, A. O.; Raju, G.; Brenmoehl, J.; Rogler, G.; Reyes, V. E.; Powell, D. (2011):
Human colonic myofibroplasts promote expansion of CD4+ CD25high Foxp3+ regulatory T cells. Gastroenterology 140 (7): 2019-2030
Meier, J. K.-H.; Scharl, M.; Miller, S. N.; Brenmoehl, J.; Hausmann, M.; Kellermeier, S.; Schölmerich, J.; Rogler, G. (2011):
Specific differences in migratory function of myofibroblasts isolated from Crohn's disease fistulae and strictures. Inflamm Bowel Dis 17 (1): 202-212
Rieder, F.; Georgieva, M.; Schirbel, A.; Artinger, M.; Zügner, A.; Blank, M.; Brenmoehl, J.; Schölmerich, J.; Rogler, G. (2010):
Prostaglandin E2 Inhibits Migration of Colonic Lamina Propria Fibroblasts. Inflamm Bowel Dis 16 (9): 1505-1513
Kosovac, K.; Brenmoehl, J.; Holler, E.; Falk, W.; Schoelmerich, J.; Hausmann, M.; Rogler, G. (2010):
Association of the NOD2 genotype with bacterial translocation via altered cell-cell contacts in Crohn's disease patients. Inflamm Bowel Dis 16 (8): 1311-1321
Landfried, K.; Bataille, F.; Rogler, G.; Brenmoehl, J.; Kosovac, K.; Wolff, D.; Hilgendorf, I.; Hahn, J.; Edinger, M.; Hoffmann, P.; Obermeier, J.; Schoelmerich, J.; Andreesen, R.; Holler, E. (2009):
Recipient NOD2/CARD15 status affects cellular infiltrates in human intestinal graft-versus-host disease. Clin Exp Immunol 159 (1): 87-92
Pohlers, D.; Brenmoehl, J.; Löffler, I.; Müller, M.; Leipner, C.; Schultze-Mosgau, S.; Stallmach, A.; Kinne, R.; Wolf, I (2009):
TGF-β and fibrosis in different organs — molecular pathway imprints. BBA-Mol Basis Dis 1792 (8): 746-756
Lang, M.; Schlechtweg, M.; Kellermeier, S.; Brenmoehl, J.; Falk, W.; Schölmerich, J.; Herfarth, H.; Rogler, G.; Hausmann, M. (2009):
Gene expression profiles of mucosal fibroblasts from strictured and nonstrictured areas of patients with Crohn's disease. Inflamm Bowel Dis 15 (2): 212-223
Brenmoehl, J.; Miller, S. N.; Hofmann, C.; Vogl, D.; Falk, W.; Schölmerich, J.; Rogler, G. (2009):
Transforming growth factor-β1 induces intestinal myofibroblast differentiation and modulates their migration. World J Gastroentero 15 (12): 1431-1442
Brenmoehl, J.; Falk, W.; Goke, M.; Scholmerich, J.; Rogler, G. (2008):
Inflammation modulates fibronectin isoform expression in colonic lamina propria fibroblasts (CLPF). Int J Colorectal Dis 23: 947-955
Bataille, F.; Rohrmeier, C.; Bates, R.; Weber, A.; Rieder, F.; Brenmoehl, J.; Strauch, U.; Farkas, S.; Furst, A.; Hofstadter, F.; Scholmerich, J.; Herfarth, H.; Rogler, G. (2008):
Evidence for a role of epithelial mesenchymal transition during pathogenesis of fistulae in Crohn's disease. Inflamm Bowel Dis 14: 1514-1527
Lippert, E.; Gunckel, M.; Brenmoehl, J.; Bataille, F.; Falk, W.; Scholmerich, J.; Obermeier, F.; Rogler, G. (2008):
Regulation of galectin-3 function in mucosal fibroblasts: potential role in mucosal inflammation. Clin. Exp. Immunol. 152: 285-297
Holler, E.; Rogler, G.; Brenmoehl, J.; Hahn, J.; Greinix, H.; Dickinson, A. M.; Socie, G.; Wolff, D.; Finke, J.; Fischer, G.; Jackson, G.; Rocha, V.; Hilgendorf, I.; Eissner, G.; Marienhagen, J.; Andreesen, R. (2008):
The role of genetic variants of NOD2/CARD15, a receptor of the innate immune system, in GvHD and complications following related and unrelated donor haematopoietic stem cell transplantation. Int. J. Immunogenet. 35: 381-384
Holler, E.; Hahn, J.; Andreesen, R.; Rogler, G.; Brenmoehl, J.; Greinix, H.; Dickinson, A. M.; Socie, G.; Wolff, D.; Finke, J. (2008):
NOD2/CARD15 polymorphisms in allogeneic stem-cell transplantation from unrelated donors: T depletion matters. J Clin Oncol 26: 338-339
Hildebrandt, G. C.; Granell, M.; Urbano-Ispizua, A.; Wolff, D.; Hertenstein, B.; Greinix, H. T.; Brenmoehl, J.; Schulz, C.; Dickinson, A. M.; Hahn, J.; Rogler, G.; Andreesen, R.; Holler, E. (2008):
Recipient NOD2/CARD15 variants: a novel independent risk factor for the development of bronchiolitis obliterans after allogeneic stem cell transplantation. Biol Blood Marrow Transplant 14: 67-74
Brenmoehl, J.; Lang, M.; Hausmann, M.; Leeb, S. N.; Falk, W.; Scholmerich, J.; Goke, M.; Rogler, G. (2007):
Evidence for a differential expression of fibronectin splice forms ED-A and ED-B in Crohn's disease (CD) mucosa. Int J Colorectal Dis 22: 611-623
Brenmoehl, J.; Holler, E.; Rogler, G. (2007):
Polymorphisms within epithelial receptors: NOD2/CARD15. Methods Mol Med 134: 115-122
Brenmoehl, J.; Herfarth, H.; Gluck, T.; Audebert, F.; Barlage, S.; Schmitz, G.; Froehlich, D.; Schreiber, S.; Hampe, J.; Scholmerich, J.; Holler, E.; Rogler, G. (2007):
Genetic variants in the NOD2/CARD15 gene are associated with early mortality in sepsis patients. Intensive Care Med 33: 1541-1548
Rieder, F.; Brenmoehl, J.; Leeb, S.; Scholmerich, J.; Rogler, G. (2007):
Wound healing and fibrosis in intestinal disease. Gut 56: 130-139