PD Dr. rer. nat. habil. Jens Vanselow

Research Institute for Farm Animal Biology (FBN)
Head of Competence area Reproduction and Development
Head of Working group Cell Physiology & reproduction
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Research interests

  • Reproductive Biology
  • Folliculogenesis, Luteinization
  • Gene Regulation
  • Epigenetics

Curriculum Vitae

  • 2013-present: Head of the Institute of Reproductive Biology, Leibniz Institute for Farm Animal Biology (FBN) Dummerstorf
  • 2002: Habilitation and Lecturer at the Faculty of Mathematics and Natural Sciences and the Faculty of Agricultural and Environmental Sciences at the University of Rostock
  • 1992-2012: Head of the Gene Regulation Group at the Leibniz Institute for Farm Animal Biology (FBN) Dummerstorf, Research Unit Molecular Biology
  • 1990-1992: Postdoctoral Grant, Boehringer Ingelheim Fonds
  • 1990-1992: Harvard Research Fellow at Massachusetts General Hospital, Institute for Developmental Biology, Boston, USA
  • 1988-1990: Member of the DFG Graduate College "Neurobiology", Eberhard Karls University Tübingen, Germany
  • 1990: Graduation (Dr. rer. nat.) at Eberhard Karls University Tübingen and Max-Planck-Institute for Developmental Biology, Tübingen, Germany
  • 1987: Diploma Biology at Eberhard Karls University Tübingen, Germany
  • 1983: Prediploma Biology at Johannes Gutenberg University Mainz, Germany


  • 2013-present: "Population Genetics, Molecular Animal Breeding and Reproductive Technology" (MSc), Faculty of Agricultural and Environmental Sciences, University of Rostock, Germany
  • 2014-present: "Breeding Programs and Reproduction Management" (B.Sc.), Faculty of Agricultural and Environmental Sciences, University of Rostock, Germany
  • 2011-present: "Molecular Animal Breeding" (MSc), Faculty of Mathematics and Natural Sciences, University of Rostock, Germany
  • 1997-2010: "Molecular Mechanisms of Development and Differentiation" (Dipl-Biol), Faculty of Mathematics and Natural Sciences, University of Rostock, Germany


Vanselow, J.; Kucia, M.; Langhammer, M.; Koczan, D.; Rehfeldt, C.; Metges, C. C. (2011):
Hepatic expression of the GH/JAK/STAT/IGF pathway, acute-phase response signalling and complement system are affected in mouse offspring by prenatal and early postnatal exposure to maternal high-protein diet. Eur J Nutr 50 (8): 611-623
Vanselow, J.; Fürbaß, R. (2011):
The bovine genome contains three differentially methylated paralogous copies of the P450c17 encoding gene (CYP17A1). Gen Comp Endocr 170 (3): 475-479
Nimz, M.; Spitschak, M.; Fürbaß, R.; Vanselow, J. (2010):
The preovulatory luteinizing hormone surge is followed by downregulation of CYP19A1, HSD3B1 and CYP17A1 and chromatin condensation of the corresponding promoters in bovine follicles. Mol Reprod Dev 77: 1040-1048
Vanselow, J.; Fürbaß, R. (2010):
Epigenetic control of folliculogenesis and luteinization. Anim Reprod 7 (3): 134-139
Vanselow, J.; Langhammer, M. (2010):
Biodiversität und Leistung beim landwirtschaftlichen Nutztier. Forschungsreport 1: 20-23
Fürbaß, R.; Tomek, W.; Vanselow, J. (2010):
Upstream Stimulating Factors 1 and 2 Enhance Transcription from the Placenta-Specific Promoter 1.1 of the Bovine Cyp19 Gene. BMC Mol Biol 11: 5
Vanselow, J.; Spitschak, M.; Nimz, M.; Fürbaß, R. (2010):
DNA methylation is not involved in preovulatory down-regulation of CYP11A1, HSD3B1, and CYP19A1 in bovine follicles but may have a role in permanent silencing of CYP19A1 in large granulosa lutein cells. Biol Reprod 82 (2): 289-298
Nimz, M.; Spitschak, M.; Schneider, F.; Fürbaß, R.; Vanselow, J. (2009):
Down-regulation of genes encoding steroidogenic enzymes and hormone receptors in late preovulatory follicles of the cow coincides with an accumulation of intrafollicular steroids. DOMEST ANIM ENDOCRIN 37 (1): 45-54
Tiemann, U.; Tomek, W.; Schneider, F.; Müller, U.; Pöhland, R.; Vanselow, J. (2009):
The mycotoxins alternariol and alternariol methyl ether negatively affect progesterone synthesis in porcine granulosa cells in vitro. Toxicol lett 186 (2): 139-145
Vanselow, J.; Selimyan, R.; Fürbaß, R. (2008):
DNA methylation of placenta-specific Cyp19 promoters of cattle and sheep. Exp Clin Endocr Diab 116 (7): 437-442
Tiemann, U.; Brüssow, K.-P.; Dänicke, S.; Vanselow, J. (2008):
Feeding of pregnant sows with mycotoxin-contaminated diets and their non-effect on foetal and maternal hepatic transcription of genes of the insulin-like growth factor system. Food Addit Contam 25 (11): 1365-1373
Vanselow, J.; Nürnberg, G.; Koczan, D.; Langhammer, M.; Thiesen, H.-J.; Reinsch, N. (2008):
Expression profiling of a high-fertility mouse line by microarray analysis and qPCR. BMC Genomics 9 (1): 307
Vanselow, J.; Fürbaß, R.; Tiemann, U. (2008):
Cultured bovine trophoblast cells differentially express genes encoding key steroid synthesis enzymes. Placenta 29 (6): 531-538
Fürbaß, R.; Selimyan, R.; Vanselow, J. (2008):
DNA methylation and chromatin accessibility of the proximal Cyp19 promoter region 1.5/2 correlate with expression levels in sheep placentomes. Mol Reprod Dev 75 (1): 1-7
Spitschak, M.; Langhammer, M.; Schneider, F.; Renne, U.; Vanselow, J. (2007):
Two high-fertility mouse lines show differences in component fertility traits after long-term selection. Reprod Fert Develop 19 (7): 815-821
Tiemann, U.; Schneider, F.; Vanselow, J.; Tomek, W. (2007):
In vitro exposure of porcine granulosa cells to the phytoestrogens genistein and daidzein: Effects on the biosynthesis of reproductive steroid hormones. Reprod Toxicol 24 (3-4): 317-325
Nausch, Norman; Manteuffel, G.; Vanselow, J. (2007):
0.2kb promoter sequence of the murine Cyp19 gene target β-galactosidase expression to specific brain areas of transgenic mice. J Steroid Biochem 103 (2): 119-128
Vanselow, J.; Yang, W.; Herrmann, J.; Zerbe, H.; Schuberth, H.-J.; Petzl, W.; Tomek, W.; Seyfert, H.-M. (2006):
DNA-remethylation around a STAT5-binding enhancer in the alpha-S1-casein promoter is associated with abrupt shut-down of alpha-S1-casein synthesis during acute mastitis. J Mol Endocrinol 37 (3): 463-477
Vanselow, J.; Viergutz, T.; Fürbaß, R. (2006):
Repression of the aromatase gene (CYP19) during luteinization coincides with DANN methylation of a specific CpG dinucleotide within promoter 2. In: Proc. 8th World Congress on Genetics Applied to Livestock Production (Comm.11-11):
Alm, H.; Brüssow, K.-P.; Torner, H.; Vanselow, J.; Tomek, W.; Dänicke, S.; Tiemann, U. (2006):
Influence of Fusarium-toxin contaminated feed on initial quality and meiotic competence of gilt oocytes. Reprod Toxicol 22 (1): 44-50