PD Dr. rer. nat. habil. Jens Vanselow
Research Institute for Farm Animal Biology (FBN)
Head of Competence area Reproduction and Development
Head of Working group Cell Physiology & Reproduction
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Head of Competence area Reproduction and Development
Head of Working group Cell Physiology & Reproduction
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Research interests
- Reproductive Biology
- Folliculogenesis, Luteinization
- Spermatogenesis
- Gene Regulation
- Epigenetics
Curriculum Vitae
- 2024-present: Head of Competence area Reproduction and Development, Research Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
- 2013-2023: Head of the Institute of Reproductive Biology, Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
- 2002: Habilitation and Lecturer at the Faculty of Mathematics and Natural Sciences and the Faculty of Agricultural and Environmental Sciences at the University of Rostock, Germany
- 1992-2012: Head of the Gene Regulation Group at the Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Research Unit Molecular Biology, Germany
- 1990-1992: Postdoctoral Grant, Boehringer Ingelheim Fonds
- 1990-1992: Harvard Research Fellow at Massachusetts General Hospital, Institute for Developmental Biology, Boston, USA
- 1988-1990: Member of the DFG Graduate College "Neurobiology", Eberhard Karls University Tübingen, Germany
- 1990: Graduation (Dr. rer. nat.) at Eberhard Karls University Tübingen and Max-Planck-Institute for Developmental Biology, Tübingen, Germany
- 1987: Diploma Biology at Eberhard Karls University Tübingen, Germany
- 1983: Prediploma Biology at Johannes Gutenberg University Mainz, Germany
Teaching
- 2023-present: “Molecular Biology of the Cell” (B.Sc.) Biosciences, Faculty of Mathematics and Natural Sciences, University of Rostock, Germany
- 2024-present: “Reproduction and Reproductive Biotechnology” (M.Sc.) Faculty of Agricultural and Environmental Sciences, University of Rostock, Germany
- 2013-present: „Population Genetics, Molecular Animal Breeding and Reproductive Technology“ (MSc), Faculty of Agricultural and Environmental Sciences, University of Rostock, Germany
- 2014-present: “Breeding Programs and Reproduction Management” (B.Sc.), Faculty of Agricultural and Environmental Sciences, University of Rostock, Germany
- 2011-present: „Molecular Animal Breeding“ (MSc), Biosciences, Faculty of Mathematics and Natural Sciences, University of Rostock, Germany
- 1997-2010: „Molecular Mechanisms of Development and Differentiation“ (Dipl-Biol), Faculty of Mathematics and Natural Sciences, University of Rostock, Germany
Publications
Pöhland, R.; Souza Cáceres, M. B.; Datta, T. K.; Vanselow, J.; Martins, M.I.M.; Silva, W.A.L.; Cardoso, C. T.; Melo Sterza, F. A. (2020):
Influence of long-term thermal stress on the in vitro maturation on embryo development and Heat Shock Protein abundance in zebu cattle. Anim Reprod 17 (3): e20190085, 1-10
https://doi.org/10.1590/1984-3143-AR2019-0085
Baddela, V. S.; Sharma, A.; Vanselow, J. (2020):
Non-esterified fatty acids in the ovary: friends or foes?. Reprod Biol Endocrin 18: 60, 1-14
https://doi.org/10.1186/s12958-020-00617-9
Baddela, V. S.; Sharma, A.; Michaelis, M.; Vanselow, J. (2020):
HIF1 driven transcriptional activity regulates steroidogenesis and proliferation of bovine granulosa cells. Sci Rep-UK 10: 3906
https://doi.org/10.1038/s41598-020-60935-1
Sharma, A.; Baddela, V. S.; Roettgen, V.; Vernunft, A.; Viergutz, T.; Dannenberger, D.; Hammon, H. M.; Schoen, J.; Vanselow, J. (2020):
Effects of dietary fatty acids on bovine oocyte competence and granulosa cells. Front Endocrinol 11: 87, 1-12
https://doi.org/10.3389/fendo.2020.00087
Vanselow, J.; Christenson, L. K.; Pate, J. L. (2020):
Editorial: Regulation of dynamic changes and remodeling events during the formation, rescue and regression of the corpus luteum. Front Endocrinol 11: 244, 1-2
https://doi.org/10.3389/fendo.2020.00244
Sharma, A.; Baddela, V. S.; Becker, D.; Dannenberger, D.; Viergutz, T.; Vanselow, J. (2019):
Elevated free fatty acids affect bovine granulosa cell function: a molecular cue for compromised reproduction during negative energy balance. Endocr Connect 8 (5): 493-505
https://doi.org/10.1530/EC-19-0011
Baufeld, A.; Koczan, D.; Vanselow, J. (2019):
L-lactate induces specific genome wide alterations of gene expression in cultured bovine granulosa cells. BMC Genomics 20: 273, 1-11
https://doi.org/10.1186/s12864-019-5657-6
Baufeld, A.; Vanselow, J. (2018):
A tissue culture model of estrogen-producing primary bovine granulosa cells. 139: e58208
https://doi.org/doi:10.3791/58208
Baddela, V. S.; Sharma, A.; Koczan, D.; Viergutz, T.; Vernunft, A.; Vanselow, J. (2018):
mRNA microarraydata of FACS purified bovine small and large luteal cells. Data in brief 19: 737-742
https://doi.org/10.1016/j.dib.2018.05.029
Baddela, V. S.; Sharma, A.; Viergutz, T.; Koczan, D.; Vanselow, J. (2018):
Low oxygen levels induce early luteinization associated changes in bovine granulosa cells. Front Physiol 9: 1066, 1-15
https://doi.org/10.3389/fphys.2018.01066
Baufeld, A.; Vanselow, J. (2018):
Lactate promotes specific differentiation in bovine granulosa cells depending on lactate uptake thus mimicking an early post-LH stage. Reprod Biol Endocrin 16: 15, 1-11
https://doi.org/10.1186/s12958-018-0332-3
Baddela, V. S.; Koczan, D.; Viergutz, T.; Vernunft, A.; Vanselow, J. (2018):
Global gene expression analysis indicates that small luteal cells are involved in extracellular matrix modulation and immune cell recruitment in the bovine corpus luteum. Mol Cell Endocrinol 474: 201-213
https://doi.org/10.1016/j.mce.2018.03.011
Yenuganti, V.; Vanselow, J. (2017):
Oleic acid induces down-regulation of the granulosa cell identity marker FOXL2, and up-regulation of the Sertoli cell marker SOX9 in bovine granulosa cells. Reprod Biol Endocrin 15: 57, 1-5
https://doi.org/10.1186/s12958-017-0276-z
Yenuganti, V.; Vanselow, J. (2017):
Cultured bovine granulosa cells rapidly lose important features of their identity and functionality but partially recover under long-term culture conditions. Cell Tissue Res 368 (2): 397-403
https://dx.doi.org/10.1007/s00441-017-2571-6
Baufeld, A.; Koczan, D.; Vanselow, J. (2017):
Induction of altered gene expression profiles in cultured bovine granulosa cells at high cell density. Reprod Biol Endocrin 15: 3, 1-14
https://dx.doi.org/10.1186/s12958-016-0221-6
Vanselow, J.; Vernunft, A.; Koczan, D.; Spitschak, M.; Kuhla, B. (2016):
Exposure of lactating dairy cows to acute pre-ovulatory heat stress affects granulosa cell-specific gene expression profiles in dominant follicles. Plos One 11 (8): e0160600, 1-19
https://dx.doi.org/10.1371/journal.pone.0160600
Yenuganti, V.; Viergutz, T.; Vanselow, J. (2016):
Oleic acid induces specific alterations in the morphology, gene expression and steroid hormone production of cultured bovine granulosa cells. Gen Comp Endocr 232: 134-144
https://dx.doi.org/10.1016/j.ygcen.2016.04.020
Vanselow, J.; Kucia, M.; Langhammer, M.; Koczan, D.; Metges, C. C. (2016):
Maternal high-protein diet during pregnancy, but not during suckling, induced altered expression of an increasing number of hepatic genes in adult mouse offspring. Eur J Nutr 55 (3): 917-930
https://dx.doi.org/10.1007/s00394-015-0906-1
Rudolf, H.; Nuernberg, G.; Koczan, D.; Vanselow, J.; Gempe, T.; Beye, M.; Leboulle, G.; Bienefeld, K.; Reinsch, N. (2015):
On the relevance of technical variation due to building pools in microarray experiments. BMC Genomics 16: 1027, 1-12
https://dx.doi.org/10.1186/s12864-015-2055-6
Kunze, M.; Wirthgen, E.; Walz, C.; Spitschak, M.; Brenmoehl, J.; Vanselow, J.; Schwerin, M.; Wimmers, K.; Hoeflich, A. (2015):
Bioanalytical validation for simultaneous quantification of non-aromatic steroids in follicular fluid from cattle via ESI-LC-MS/MS. J Chromatogr B 1007: 132-139
https://dx.doi.org/10.1016/j.jchromb.2015.10.010