About Us

PD Dr. rer. nat. habil. Jens Vanselow

+49 38208 68-750
vanselow@fbn-dummerstorf.de
Research Institute for Farm Animal Biology (FBN)
Head of Competence area Reproduction and Development
Head of Working group Cell Physiology & reproduction
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Research interests

  • Reproductive Biology
  • Folliculogenesis, Luteinization
  • Gene Regulation
  • Epigenetics

Curriculum Vitae

  • 2013-present: Head of the Institute of Reproductive Biology, Leibniz Institute for Farm Animal Biology (FBN) Dummerstorf
  • 2002: Habilitation and Lecturer at the Faculty of Mathematics and Natural Sciences and the Faculty of Agricultural and Environmental Sciences at the University of Rostock
  • 1992-2012: Head of the Gene Regulation Group at the Leibniz Institute for Farm Animal Biology (FBN) Dummerstorf, Research Unit Molecular Biology
  • 1990-1992: Postdoctoral Grant, Boehringer Ingelheim Fonds
  • 1990-1992: Harvard Research Fellow at Massachusetts General Hospital, Institute for Developmental Biology, Boston, USA
  • 1988-1990: Member of the DFG Graduate College "Neurobiology", Eberhard Karls University Tübingen, Germany
  • 1990: Graduation (Dr. rer. nat.) at Eberhard Karls University Tübingen and Max-Planck-Institute for Developmental Biology, Tübingen, Germany
  • 1987: Diploma Biology at Eberhard Karls University Tübingen, Germany
  • 1983: Prediploma Biology at Johannes Gutenberg University Mainz, Germany

Teaching

  • 2013-present: "Population Genetics, Molecular Animal Breeding and Reproductive Technology" (MSc), Faculty of Agricultural and Environmental Sciences, University of Rostock, Germany
  • 2014-present: "Breeding Programs and Reproduction Management" (B.Sc.), Faculty of Agricultural and Environmental Sciences, University of Rostock, Germany
  • 2011-present: "Molecular Animal Breeding" (MSc), Faculty of Mathematics and Natural Sciences, University of Rostock, Germany
  • 1997-2010: "Molecular Mechanisms of Development and Differentiation" (Dipl-Biol), Faculty of Mathematics and Natural Sciences, University of Rostock, Germany

Publications

Tao, X.; Rahimi, M.; Michaelis, M.; Görs, S.; Brenmoehl, J.; Vanselow, J.; Baddela, V. S. (2024):
Saturated fatty acids inhibit unsaturated fatty acid induced glucose uptake involving GLUT10 and aerobic glycolysis in bovine granulosa cells
Marten Michaelis, Solvig Görs, Julia Brenmoehl, Jens Vanselow, Vijay Simha Baddela
Scientific reports 14: 9888, 1-15
https://doi.org/10.1038/s41598-024-59883-x
Vanselow, J.; Wesenauer, C.; Eggert, A.; Sharma, A.; Becker, F. (2024):
Summer heat during spermatogenesis reduces in vitro blastocyst rates and affects sperm quality of next generation bulls [epublished ahead of print].
Jens Vanselow, Anja Eggert, Frank Becker
Andrology
https://doi.org/10.1111/andr.13627
Röttgen, V.; Tümmler, L.-M.; Koczan, D.; Rebl, A.; Kuhla, B.; Vanselow, J.; Baufeld, A. (2023):
Early milk-feeding regimes in calves exert long-term effects on the development of ovarian granulosa cells. BMC Genomics 24: 485, 1-13
Volker Röttgen, Alexander Rebl, Björn Kuhla, Jens Vanselow, Anja Baufeld
Baddela, V. S.; Michaelis, M.; Tao, X.; Koczan, D.; Vanselow, J. (2023):
ERK1/2-SOX9/FOXL2 axis regulates ovarian steroidogenesis and favors the follicular-luteal transition. LIFE SCI ALLIANCE 6 (10): e202302100, 1-13
Vijay Simha Baddela, Marten Michaelis, Jens Vanselow
Pöhland, R.; Vanselow, J.; Melo-Sterza, F.D. (2023):
Translocation of Oocytic HES1 into Surrounding Cumulus Cells in Bovine: Mechanism of Cellular Interaction during IVM? [epublished ahead of print]. Int J Mol Sci 24 (15): 11932, 1-10
Ralf Pöhland, Jens Vanselow
Baddela, V. S.; Michaelis, M.; Sharma, A.; Plinski, C.; Viergutz, T.; Vanselow, J. (2022):
Estradiol production of granulosa cells is unaffected by the physiological mix of non-esterified fatty acids in follicular fluid. J Biol Chem 298 (10): 102477, 1-11
Vijay Simha Baddela, Marten Michaelis, Jens Vanselow
Baddela, V. S.; Sharma, A.; Plinski, C.; Vanselow, J. (2022):
Palmitic acid protects granulosa cells from oleic acid induced steatosis and rescues progesterone production via cAMP dependent mechanism. BBA-MOL CELL BIOL L 1867 (8): 159159, 1-11
Vijay Simha Baddela, Jens Vanselow
https://doi.org/10.1016/j.bbalip.2022.159159
Baufeld, A.; Vanselow, J. (2022):
Lactate-induced effects on bovine granulosa cells are mediated via PKA signaling. Cell Tissue Res 388 (2): 471-477
Anja Baufeld, Jens Vanselow
https://doi.org/10.1007/s00441-021-03569-7
Berger, T; Vanselow, J.; Conley, A. J.; Almand, T. J.; Nitta-Oda, B. S. (2022):
Multifaceted epigenetic regulation of porcine testicular aromatase. Mol Cell Endocrinol 541: 111526, 1-8
Jens Vanselow
https://doi.org/10.1016/j.mce.2021.111526
Vanselow, J.; Conley, A. J.; Berger, T (2021):
Aromatase and the three little paralogs. Biol Reprod 105 (1): 5-6
Jens Vanselow
https://doi.org/10.1093/biolre/ioab112
Yenuganti, V.; Koczan, D.; Vanselow, J. (2021):
Genome wide effects of oleic acid on cultured bovine granulosa cells: evidence for the activation of pathways favoring folliculo-luteal transition. BMC Genomics 22: 486, 1-10
Jens Vanselow
https://doi.org/10.1186/s12864-021-07817-6
Vanselow, J.; Conley, A. J.; Corbin, C. J.; Berger, T (2021):
Genomic Structure of the Porcine CYP19 Locus and Expression of the CYP19A3 Paralog . Genes-Basel 12 (4): 533, 1-12
Jens Vanselow
https://doi.org/10.3390/genes12040533
Pöhland, R.; Souza Cáceres, M. B.; Datta, T. K.; Vanselow, J.; Martins, M.I.M.; Silva, W.A.L.; Cardoso, C. T.; Melo Sterza, F. A. (2020):
Influence of long-term thermal stress on the in vitro maturation on embryo development and Heat Shock Protein abundance in zebu cattle. Anim Reprod 17 (3): e20190085, 1-10
Ralf Pöhland, Jens Vanselow
https://doi.org/10.1590/1984-3143-AR2019-0085
Baddela, V. S.; Sharma, A.; Vanselow, J. (2020):
Non-esterified fatty acids in the ovary: friends or foes?. Reprod Biol Endocrin 18: 60, 1-14
Vijay Simha Baddela, Jens Vanselow
https://doi.org/10.1186/s12958-020-00617-9
Baddela, V. S.; Sharma, A.; Michaelis, M.; Vanselow, J. (2020):
HIF1 driven transcriptional activity regulates steroidogenesis and proliferation of bovine granulosa cells. Sci Rep-UK 10: 3906
Vijay Simha Baddela, Marten Michaelis, Jens Vanselow
https://doi.org/10.1038/s41598-020-60935-1
Sharma, A.; Baddela, V. S.; Roettgen, V.; Vernunft, A.; Viergutz, T.; Dannenberger, D.; Hammon, H. M.; Schoen, J.; Vanselow, J. (2020):
Effects of dietary fatty acids on bovine oocyte competence and granulosa cells. Front Endocrinol 11: 87, 1-12
Vijay Simha Baddela, Volker Röttgen, Andreas Vernunft, Dirk Dannenberger, Harald Michael Hammon, Jens Vanselow
https://doi.org/10.3389/fendo.2020.00087
Vanselow, J.; Christenson, L. K.; Pate, J. L. (2020):
Editorial: Regulation of dynamic changes and remodeling events during the formation, rescue and regression of the corpus luteum. Front Endocrinol 11: 244, 1-2
Jens Vanselow
https://doi.org/10.3389/fendo.2020.00244
Sharma, A.; Baddela, V. S.; Becker, D.; Dannenberger, D.; Viergutz, T.; Vanselow, J. (2019):
Elevated free fatty acids affect bovine granulosa cell function: a molecular cue for compromised reproduction during negative energy balance. Endocr Connect 8 (5): 493-505
Vijay Simha Baddela, Frank Becker, Dirk Dannenberger, Jens Vanselow
https://doi.org/10.1530/EC-19-0011
Baufeld, A.; Koczan, D.; Vanselow, J. (2019):
L-lactate induces specific genome wide alterations of gene expression in cultured bovine granulosa cells. BMC Genomics 20: 273, 1-11
Anja Baufeld, Jens Vanselow
https://doi.org/10.1186/s12864-019-5657-6
Baufeld, A.; Vanselow, J. (2018):
A tissue culture model of estrogen-producing primary bovine granulosa cells. 139: e58208
Anja Baufeld, Jens Vanselow
https://doi.org/doi:10.3791/58208