PD Dr. rer. nat. habil. Jens Vanselow
Research Institute for Farm Animal Biology (FBN)
Head of Competence area Reproduction and Development
Head of Working group Cell Physiology & Reproduction
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Head of Competence area Reproduction and Development
Head of Working group Cell Physiology & Reproduction
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Research interests
- Reproductive Biology
- Folliculogenesis, Luteinization
- Spermatogenesis
- Gene Regulation
- Epigenetics
Curriculum Vitae
- 2024-present: Head of Competence area Reproduction and Development, Research Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
- 2013-2023: Head of the Institute of Reproductive Biology, Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
- 2002: Habilitation and Lecturer at the Faculty of Mathematics and Natural Sciences and the Faculty of Agricultural and Environmental Sciences at the University of Rostock, Germany
- 1992-2012: Head of the Gene Regulation Group at the Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Research Unit Molecular Biology, Germany
- 1990-1992: Postdoctoral Grant, Boehringer Ingelheim Fonds
- 1990-1992: Harvard Research Fellow at Massachusetts General Hospital, Institute for Developmental Biology, Boston, USA
- 1988-1990: Member of the DFG Graduate College "Neurobiology", Eberhard Karls University Tübingen, Germany
- 1990: Graduation (Dr. rer. nat.) at Eberhard Karls University Tübingen and Max-Planck-Institute for Developmental Biology, Tübingen, Germany
- 1987: Diploma Biology at Eberhard Karls University Tübingen, Germany
- 1983: Prediploma Biology at Johannes Gutenberg University Mainz, Germany
Teaching
- 2023-present: “Molecular Biology of the Cell” (B.Sc.) Biosciences, Faculty of Mathematics and Natural Sciences, University of Rostock, Germany
- 2024-present: “Reproduction and Reproductive Biotechnology” (M.Sc.) Faculty of Agricultural and Environmental Sciences, University of Rostock, Germany
- 2013-present: „Population Genetics, Molecular Animal Breeding and Reproductive Technology“ (MSc), Faculty of Agricultural and Environmental Sciences, University of Rostock, Germany
- 2014-present: “Breeding Programs and Reproduction Management” (B.Sc.), Faculty of Agricultural and Environmental Sciences, University of Rostock, Germany
- 2011-present: „Molecular Animal Breeding“ (MSc), Biosciences, Faculty of Mathematics and Natural Sciences, University of Rostock, Germany
- 1997-2010: „Molecular Mechanisms of Development and Differentiation“ (Dipl-Biol), Faculty of Mathematics and Natural Sciences, University of Rostock, Germany
Publications
Tao, X.; Brenmoehl, J.; Marten, M.; Vanselow, J.; Baddela, V. (2025):
CD36 regulates glucose metabolism but not fatty acid uptake in bovine granulosa cells
Molecular and Cellular Endocrinology 613: 112717, 1-11
https://doi.org/10.1016/j.mce.2025.112717
Tao, X.; Brenmoehl, J.; Koczan, D.; Vanselow, J.; Baddela, V. S. (2025):
PDK4 is critical for metabolic regulation and progesterone production in bovine granulosa cells
Biology of Reproduction: ioaf238, 1-14
https://doi.org/10.1093/biolre/ioaf238
Sharma, A.; Vanselow, J.; Kühn, C.; Becker, D. (2025):
Functional characterization of a bovine luteal cell culture model: Effects of passage number
PLoS One 20 (11): e0334047, 1-16
https://doi.org/10.1371/journal.pone.0334047
Baufeld, A.; Vanselow, J. (2025):
A Modified Co-Culture System for Understanding Granulosa-Theca Cell Interactions in the Bovine Ovary
Journal of Visualized Experiments 223: e68589, 1-16
https://doi.org/10.3791/68589
Corte Pause, F.; Baufeld, A.; Urli, S.; Crociati, M.; Stradaioli, G.; Vanselow, J.; Kalbe, C. (2025):
Exploring the influence of polystyrene-nanoplastics on two distinct in vitro systems in farm animals: A pilot study
Science of the Total Environment 976: 179378, 1-10
https://doi.org/10.1016/j.scitotenv.2025.179378
Baddela, V. S.; Michaelis, M.; Tao, X.; Koczan, D.; Brenmoehl, J.; Vanselow, J. (2025):
Comparative analysis of PI3K-AKT and MEK-ERK1/2 signaling-driven molecular changes in granulosa cells
Reproduction 169 (2): e240317, 1-13
https://doi.org/10.1530/REP-24-0317
Pöhland, R.; Souza-Cáceres, M. B.; Datta, T. K.; Vanselow, J.; Silva, W. A. L. da; Cardoso, C. J. T.; Sterza, F. de A. M. (2024):
Influence of thermal stress during in vitro maturation on the developmental competence of oocytes and embryos and the expression of Sirtuins in cumulus oocyte complexes in cattle
Semina: Ciências Agrárias 46 (1), 149-168
https://doi.org/10.5433/1679-0359.2025v46n1p149
Sharma, A.; Becker, F.; Tao, X.; Baddela, V. S.; Koczan, D.; Ludwig, C.; Vanselow, J. (2024):
Hyperplastic ovarian stromal cells express genes associated to tumor progression: a case study
BMC Veterinary Research 20: 439, 1-19
https://doi.org/10.1186/s12917-024-04275-6
Tao, X.; Rahimi, M.; Michaelis, M.; Görs, S.; Brenmoehl, J.; Vanselow, J.; Baddela, V. S. (2024):
Saturated fatty acids inhibit unsaturated fatty acid induced glucose uptake involving GLUT10 and aerobic glycolysis in bovine granulosa cells
Scientific Reports 14: 9888, 1-15
https://doi.org/10.1038/s41598-024-59883-x
Vanselow, J.; Wesenauer, C.; Eggert, A.; Sharma, A.; Becker, F. (2024):
Summer heat during spermatogenesis reduces in vitro blastocyst rates and affects sperm quality of next generation bulls
Andrology 12 (8): 1897-1906
https://doi.org/10.1111/andr.13627
Röttgen, V.; Tümmler, L.-M.; Koczan, D.; Rebl, A.; Kuhla, B.; Vanselow, J.; Baufeld, A. (2023):
Early milk-feeding regimes in calves exert long-term effects on the development of ovarian granulosa cells
BMC Genomics 24: 485, 1-13
https://doi.org/10.1186/s12864-023-09589-7
Baddela, V. S.; Michaelis, M.; Tao, X.; Koczan, D.; Vanselow, J. (2023):
ERK1/2-SOX9/FOXL2 axis regulates ovarian steroidogenesis and favors the follicular–luteal transition
Life Science Alliance 6 (10): e202302100, 1-13
https://doi.org/10.26508/lsa.202302100
Pöhland, R.; Vanselow, J.; Melo-Sterza, F.D. (2023):
Translocation of Oocytic HES1 into Surrounding Cumulus Cells in Bovine: Mechanism of Cellular Interaction during IVM?
International Journal of Molecular Sciences 24 (15): 11932, 1-10
https://doi.org/10.3390/ijms241511932
Baddela, V. S.; Michaelis, M.; Sharma, A.; Plinski, C.; Viergutz, T.; Vanselow, J. (2022):
Estradiol production of granulosa cells is unaffected by the physiological mix of nonesterified fatty acids in follicular fluid
Journal of Biological Chemistry 298 (10): 102477, 1-11
https://doi.org/10.1016/j.jbc.2022.102477
Baddela, V. S.; Sharma, A.; Plinski, C.; Vanselow, J. (2022):
Palmitic acid protects granulosa cells from oleic acid induced steatosis and rescues progesterone production via cAMP dependent mechanism
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1867 (8): 159159, 1-11
https://doi.org/10.1016/j.bbalip.2022.159159
Baufeld, A.; Vanselow, J. (2022):
Lactate-induced effects on bovine granulosa cells are mediated via PKA signaling
Cell Tissue Research 388 (2): 471-477
https://doi.org/10.1007/s00441-021-03569-7
Berger, T; Vanselow, J.; Conley, A. J.; Almand, T. J.; Nitta-Oda, B. S. (2022):
Multifaceted epigenetic regulation of porcine testicular aromatase
Molecular and Cellular Endocrinology 541: 111526, 1-8
https://doi.org/10.1016/j.mce.2021.111526
Vanselow, J.; Conley, A. J.; Berger, T (2021):
Aromatase and the three little paralogs. Biol Reprod 105 (1): 5-6
https://doi.org/10.1093/biolre/ioab112
Yenuganti, V.; Koczan, D.; Vanselow, J. (2021):
Genome wide effects of oleic acid on cultured bovine granulosa cells: evidence for the activation of pathways favoring folliculo-luteal transition. BMC Genomics 22: 486, 1-10
https://doi.org/10.1186/s12864-021-07817-6
Vanselow, J.; Conley, A. J.; Corbin, C. J.; Berger, T (2021):
Genomic Structure of the Porcine CYP19 Locus and Expression of the CYP19A3 Paralog
. Genes-Basel 12 (4): 533, 1-12
https://doi.org/10.3390/genes12040533