Dipl.-Inf. Frieder Hadlich

+49 38208 68-702
Research Institute for Farm Animal Biology (FBN)
Institute of Genome Biology
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Publications

Murani, E.; Trakooljul, N.; Hadlich, F.; Ponsuksili, S.; Wimmers, K. (2022):
Brain transcriptome responses to dexamethasone depending on dose and sex reveal factors contributing to sex-specific vulnerability to stress-induced disorders. Neuroendocrinology 112 (3): 235-251
https://doi.org/10.1159/000516500
Li, Z.; Trakooljul, N.; Hadlich, F.; Ponsuksili, S.; Wimmers, K.; Murani, E. (2021):
Transcriptome analysis of porcine PBMCs reveals lipopolysaccharide-induced immunomodulatory responses and crosstalk of immune and glucocorticoid receptor signaling. Virulence 12 (1): 1808-1824
https://doi.org/10.1080/21505594.2021.1948276
Becker, D.; Weikard, R.; Hadlich, F.; Kühn, Ch. (2021):
Single-cell RNA sequencing of freshly isolated bovine milk cells and cultured primary mammary epithelial cells. Sci Data 8: 177, 1-9
Ali, A.; Hadlich, F.; Abbas, M.; Iqbal, M. A.; Tesfaye, D.; Bouma, G.; Winger, Q.; Ponsuksili, S. (2021):
MicroRNA–mRNA Networks in Pregnancy Complications: A Comprehensive Downstream Analysis of Potential Biomarkers. Int J Mol Sci 22: 2313, 1-22
https://doi.org/10.3390/ijms22052313
Ali, A.; Murani, E.; Hadlich, F.; Liu, X; Wimmers, K.; Ponsuksili, S. (2021):
Prenatal Skeletal Muscle Transcriptome Analysis Reveals Novel MicroRNA-mRNA Networks Associated with Intrauterine Growth Restriction in Pigs. Cells-Basel 10 (5): 1007, 1-21
https://doi.org/10.3390/cells10051007
Ali, A.; Murani, E.; Hadlich, F.; Liu, X; Wimmers, K.; Ponsuksili, S. (2021):
In Utero Fetal Weight in Pigs Is Regulated by microRNAs and Their Target Genes. Genes-Basel 12 (8): 1264, 1-16
https://doi.org/10.3390/genes12081264
Iqbal, M. A.; Ali, A.; Hadlich, F.; Oster, M.; Reyer, H.; Trakooljul, N.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K.; Ponsuksili, S. (2021):
Dietary phosphorus and calcium in feed afects miRNA profles and their mRNA targets in jejunum of two strains of laying hens. Sci Rep-UK 11: 13534, 1-19
https://doi.org/10.1038/s41598-021-92932-3
Ponsuksili, S.; Hadlich, F.; Reyer, H.; Oster, M.; Trakooljul, N.; Iqbal, M. A.; Sommerfeld, V.; Rodehutscord, M.; Wimmers, K. (2021):
Genetic background and production periods shape the microRNA profiles of the gut in laying hens. Genomics 113 (4): 1790-1801
https://doi.org/10.1016/j.ygeno.2021.04.018
Ponsuksili, S.; Oster, M.; Reyer, H.; Hadlich, F.; Trakooljul, N.; Rodehutscord, M.; Camarinha-Silva, A.; Bennewitz, J.; Wimmers, K. (2021):
Genetic regulation and heritability of miRNA and mRNA expression link to phosphorus utilization and gut microbiome. Open Biol 11 (2): 200182, 1-11
https://doi.org/10.1098/rsob.200182
Gley, K.; Hadlich, F.; Trakooljul, N.; Haack, F.; Murani, E.; Gimsa, U.; Wimmers, K.; Ponsuksili, S. (2021):
Multi-Transcript Level Profiling Revealed Distinct mRNA, miRNA, and tRNA-Derived Fragment Bio-Signatures for Coping Behavior Linked Haplotypes in HPA Axis and Limbic System. Front Genet 12: 635794, 1-18
https://doi.org/10.3389/fgene.2021.635794
Hadlich, F.; Reyer, H.; Oster, M.; Trakooljul, N.; Murani, E.; Ponsuksili, S.; Wimmers, K. (2021):
rePROBE: Workflow for Revised Probe Assignment and Updated Probe-set Annotation in Microarrays. GENOM PROTEOM BIOINF 19 (6): 1043-1049
https://doi.org/10.1016/j.gpb.2020.06.007
de los Rios Pérez, L.; Brunner, R. M.; Hadlich, F.; Rebl, A.; Kühn, C.; Wittenburg, D.; Goldammer, T.; Verleih, M. (2020):
Comparative analysis of the transcriptome and distribution of putative SNPs in two rainbow trout (Oncorhynchus mykiss) breeding strains by using next-generation sequencing. Genes-Basel 11: 841, 1-16
https://doi.org/10.3390/genes11080841
Ponsuksili, S.; Reyer, H.; Hadlich, F.; Weber, F. M.; Trakooljul, N.; Oster, M.; Siengdee, P.; Muráni, E.; Rodehutscord, M.; Camarinha-Silva, A.; Bennewitz, J.; Wimmers, K. (2020):
Identification of the key molecular drivers of phosphorus utilization based on host miRNA-mRNA and gut microbiome interactions. Int J Mol Sci 21: 2818, 1-18
https://doi.org/10.3390/ijms21082818
Swirplies, F.; Würtz, S.; Baßmann, B.; Orban, A.; Schäfer, N.; Brunner, R. M.; Hadlich, F.; Goldammer, T.; Rebl, A. (2019):
Identification of molecular stress indicators in pikeperch Sander lucioperca correlating with rising water temperatures. Aquaculture 501: 260-271
https://doi.org/10.1016/j.aquaculture.2018.11.043
Muráni, E.; Trakooljul, N.; Hadlich, F.; Ponsuksili, S.; Wimmers, K. (2019):
Transcriptome responses to dexamethasone depending on dose and glucocorticoid receptor sensitivity in the liver. Front Genet 10: 559, 1-12
https://doi.org/10.3389/fgene.2019.00559
Brodhagen, J.; Weikard, R.; Thom, U.; Heimes, A.; Günther, J.; Hadlich, F.; Zerbe, H.; Petzl, W.; Meyerholz, M. M.; Hoedemaker, M.; Schubert, H-J; Engelmann, S.; Kühn, Ch. (2019):
Development and evaluation of a milk protein transcript depletion method for differential transcriptome analysis in mammary gland tissue. BMC Genomics 20 (1): 400, 1-19
https://doi.org/10.1186/s12864-019-5781-3
Haack, F.; Trakooljul, N.; Gley, K.; Murani, E.; Hadlich, F.; Wimmers, K.; Ponsuksili, S. (2019):
Deep sequencing of small non-coding RNA highlights brain-specific expression patterns and RNA cleavage. RNA Biol 16 (12): 1764-1774
https://doi.org/10.1080/15476286.2019.1657743
Ponsuksili, S.; Trakooljul, N.; Sajjanar, B.; Hadlich, F.; Murani, E.; Wimmers, K. (2019):
Epigenome-wide skeletal muscle DNA methylation profiles at the background of distinct metabolic types and ryanodine receptor variation in pigs. BMC Genomics 20: 492, 1-16
https://doi.org/10.1186/s12864-019-5880-1
Ponsuksili, S.; Trakooljul, N.; Hadlich, F.; Methling, K.; Lalk, M.; Murani, E.; Wimmers, K. (2019):
Genetic regulation of liver metabolites and transcripts linking to biochemical-llinical parameters. Front Genet 10: 348, 1-15
https://doi.org/10.3389/fgene.2019.00348
Nguinkal, J. A.; Brunner, R. M.; Verleih, M.; Rebl, A.; de los Rios Pérez, L.; Schäfer, N.; Hadlich, F.; Stüeken, M.; Wittenburg, D.; Goldammer, T. (2019):
The first highly contiguous genome assembly of pikeperch (Sander lucioperca), an emerging aquaculture species in Europe. Genes-Basel 10: 708, 1-14
https://doi.org/10.3390/genes10090708