Dr. agr. Eduard Muráni
Research interests
- Molecular biology and genetics of traits related to production, adaptation, and welfare in pigs, in particular stress response, behaviour, and muscle development
- Regulation of mRNA expression
- Biology connecting genetic with phenotypic variation
Curriculum Vitae
- 2014-present: Scientist, Genomics Unit, Leibniz Institute for Farm Animal Biology (FBN)
- 2009-2014: Junior Group Leader, Genomics Unit, Leibniz Institute for Farm Animal Biology (FBN),
- 2004-2009: Scientist, Genomics Unit, Leibniz Institute for Farm Animal Biology (FBN)
- 2002-2004: Postdoctoral Fellow, EU Project PorDictor, Inst. Of Animal Science, University of Bonn, Germany
- 2003: Ph.D. in Agricultural Science
- 1998-2002: PhD Student, Inst. Of Animal Science, University of Bonn, Germany
- 1993-1998: MSc, Constantine the Philosopher University (UKF), Nitra, Slovakia
Publications
Yang, X.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2013):
Association of TLR5 sequence variants and mRNA level with cytokine transcription in pigs. Immunogenetics 65 (2): 125-132
https://dx.doi.org/10.1007/s00251-012-0662-9
Rangkasenee, N.; Muràni, E.; Brunner, R. M.; Schellander, K.; Cinar, M. U.; Scholz, A. M.; Luther, H.; Hofer, A.; Ponsuksili, S.; Wimmers, K. (2013):
KRT8, FAF1 and PTH1R gene polymorphisms are associated with leg weakness traits in pigs. Mol Biol Rep 39 (4): 2859-2866
https://dx.doi.org/10.1007/s11033-012-2301-9
Chomwisarutkun, K.; Muràni, E.; Brunner, R. M.; Ponsuksili, S.; Wimmers, K. (2013):
QTL region-specific microarrays reveal differential expression of positional candidate genes of signaling pathways associated with the liability for the inverted teat defect. Anim Genet 44 (2): 139-148
https://dx.doi.org/10.1111/j.1365-2052.2012.02378.x
Yang, X.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2012):
Association of TLR4 polymorphism with cytokine expression level and pulmonary lesion score in pigs. Mol Biol Rep 39 (6): 7003-7009
https://dx.doi.org/10.1007/s11033-012-1530-2
Do, V. A. K.; Ponsuksili, S.; Muràni, E.; Huynh, L. T. P.; Brunner, R. M.; Wimmers, K. (2012):
Detection of a polymorphic site of the porcine C8G gene and evaluation of association with haemolytic complement activity. Arch Tierzucht 55 (3): 255-262
Ponsuksili, S.; Muràni, E.; Schwerin, M.; Schellander, K.; Tesfaye, D.; Wimmers, K. (2012):
Gene expression and DNA-methylation of bovine pretransfer endometrium depending on its receptivity after in vitro-produced embryo transfer. Plos One 7 (8): 1-13
https://dx.doi.org/10.1371/journal.pone.0042402
Ponsuksili, S.; Du, Y.; Muràni, E.; Schwerin, M.; Wimmers, K. (2012):
Elucidating molecular networks that either affect or respond to plasma cortisol concentration in target tissues of liver and muscle. Genetics 192 (3): 1109-1122
https://dx.doi.org/10.1534/genetics.112.143081
Oster, M.; Muràni, E.; Metges, C. C.; Ponsuksili, S.; Wimmers, K. (2012):
Transcriptional response of skeletal muscle to a low-protein gestation diet in porcine offspring accumulates in growth- and cell cycle-regulating pathways. Physiol Genomics 44 (16): 811-818
https://dx.doi.org/10.1152/physiolgenomics.00050.2012
Oster, M.; Muràni, E.; Metges, C. C.; Ponsuksili, S.; Wimmers, K. (2012):
A low protein diet during pregnancy provokes a lasting shift of hepatic expression of genes related to cell cycle throughout ontogenesis in a porcine model. BMC Genomics 13 (1): 93-107
https://dx.doi.org/10.1186/1471-2164-13-93
Oster, M.; Muràni, E.; Metges, C. C.; Ponsuksili, S.; Wimmers, K. (2012):
A gestational high protein diet affects the abundance of muscle transcripts related to cell cycle regulation throughout development in porcine progeny. Plos One 7 (3): 1-9
https://dx.doi.org/10.1371/journal.pone.0034519
Chomwisarutkun, K.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2012):
Gene expression analysis of mammary tissue during fetal bud formation and growth in two pig breeds - indications of prenatal initiation of postnatal phenotypic differences. BMC Dev Biol 12: 13-29
https://dx.doi.org/10.1186/1471-213x-12-13
Altmann, S.; Muràni, E.; Schwerin, M.; Metges, C. C.; Wimmers, K.; Ponsuksili, S. (2012):
Maternal dietary protein restriction and excess affects offspring gene expression and methylation of non-SMC subunits of condensin I in liver and skeletal muscle. Epigenetics-US 7 (3): 239-252
https://dx.doi.org/10.4161/epi.7.3.19183
Altmann, S.; Muràni, E.; Schwerin, M.; Metges, C. C.; Wimmers, K.; Ponsuksili, S. (2012):
Somatic cytochrome c (CYCS) gene expression and promoter-specific DNA methylation in a porcine model of prenatal exposure to maternal dietary protein excess and restriction. Brit J Nutr 107 (6): 791-799
https://dx.doi.org/10.1017/S0007114511003667
Altmann, S.; Muràni, E.; Metges, C. C.; Schwerin, M.; Wimmers, K.; Ponsuksili, S. (2012):
Effect of gestational protein deficiency and excess on hepatic expression of genes related to cell cycle and proliferation in offspring from late gestation to finishing phase in pig. Mol Biol Rep 39 (6): 7095-7104
https://dx.doi.org/10.1007/s11033-012-1541-z
Reyer, H.; Muràni, E. (2012):
Ein Stück im genetischen Puzzle. Leibniz Nordost 15: 6-7
Muràni, E.; Reyer, H.; Ponsuksili, S.; Fritschka, S.; Wimmers, K. (2012):
A substitution in the ligand binding domain of the porcine glucocorticoid receptor affects activity of the adrenal gland. Plos One 7 (9): 1-10
https://dx.doi.org/10.1371/journal.pone.0045518
Brunner, R. M.; Srikanchai, T.; Muràni, E.; Wimmers, K.; Ponsuksili, S. (2012):
Genes with expression levels correlating to drip loss prove association of their polymorphism with water holding capacity of pork. Mol Biol Rep 39 (1): 97-107
https://dx.doi.org/10.1007/s11033-011-0714-5
Chomwisarutkun, K.; Muràni, E.; Ponsuksili, S.; Wimmers, K. (2012):
Microarray analysis reveals genes and functional networks relevant to the predisposition to inverted teats in pigs. J Anim Sci 90 (1): 1-15
https://dx.doi.org/10.2527/jas.2011-4269
Wimmers, K.; Do, V. A. K.; Schütze, S.; Muràni, E.; Ponsuksili, S. (2011):
The three-way relationship of polymorphisms of porcine genes encoding terminal complement components, their differential expression, and health-related phenotypes. BMC Proceedings 5 (Suppl.4): S19, 1-4
https://dx.doi.org/10.1186/1753-6561-5-S4-S19