Prof. Dr. rer. nat. habil. Cornelia Christiane Metges

Research Institute for Farm Animal Biology (FBN)
Head of working group Nutritional Physiology
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Research interests

  • Effect of pre- and early postnatal nutrition on growth and development in farm animals
  • Amino acid and energy metabolism
  • Nutrient and energy efficiency and emissions in farm animals

Curriculum Vitae

  • 2017: Professorship Biochemistry in Nutrition, University of Rostock
  • 2001-present: Director of Institute of Nutritional Physiology 'Oskar Kellner', Leibniz Institute for Farm Animal Biology (FBN) Dummerstorf
  • 2002-present: Lecturer in Animal Nutrition and Feed Science, University of Rostock
  • 2001: Habilitation in Nutritional Physiology (Dr. rer. nat. habil.), University of Potsdam
  • 1995-1997: Visiting Scientist, Massachusetts Institute of Technology, Clinical Research Center and Laboratory of Human Nutrition, Cambridge, USA
  • 1994-2001: Head, Working group 'Protein Metabolism', Dpt. Biochemistry and Physiology of Nutrition, German Institute of Human Nutrition (DIfE), Potsdam-Nuthetal
  • 1987-1994: Research Scientist, Chair of Nutrition Science, TU München
  • 1983-1987: Doctoral studies, TU München, Chair of General Chemistry and Biochemistry (1988; Doctorate in Agricultural Sciences; Dr. agr.), TU München
  • 1977-1983: Studies of Agricultural Sciences (Dipl.-Ing. agr.), TU München

Teaching

  • Since 2012: „Stoffwechsel-, Leistungs- und Pathophysiologie, Experimentelle Methoden in der Ernährungsphysiologie“, Master course Animal Science, University of Rostock
  • Since 2012: „Anatomisch-physiologische Grundlagen und experimentelle Methoden der Tierernährung“, Master course Animal Science, University of Rostock
  • Since 2010: „Zell- u. Molekularbiologie in der Ernährungs-forschung“ (Energy and Macronutrient metabolism), Master course Ökotrophologie, Christian-Albrechts-Universität zu Kiel
  • Since 2003: „Biochemie des Intermediärstoffwechsels“, Bachelor course in Agricultural Sciences, University of Rostock
  • 1994-2001: „Biochemie und Physiologie der Ernährung“, Master course in Nutrition Science, University of Potsdam
  • 1989-1993: „Various Aspects of Human Nutrition“ in Nutrition Science, Chair of Nutrition Science, TU München

Publications

Michalski, J. P.; Kowalczyk, B.; Voigt, J.; Hammon, H. M.; Czauderna, M.; Metges, C. C. (2012):
Efficiency of endogenous urea 15N nitrogen incorporation into bacterial and milk protein of goats fed diets with three different protein levels. J Anim Feed Sci 21 (4): 599-612
https://dx.doi.org/10.22358/jafs/65918/2013
Derno, M.; Langhammer, M.; Renne, U.; Hennig, U.; Kuhla, S.; Nürnberg, G.; Klaus, S.; Brockmann, G. A.; Metges, C. C. (2012):
Mice long-term selected for high body mass are more susceptible to body fat deposition in response to a high fat diet due to insufficient increase in heat production. Arch Tierzucht 55 (6): 633-646
Mickiewicz, M.; Zabielski, R.; Grenier, B.; Le Normand, L.; Savary, G.; Holst, J. J.; Oswald, I. P.; Metges, C. C.; Guilloteau, P. (2012):
Structural and functional development of small intestine in intrauterine growth retarded porcine offspring born to gilts fed diets with differing protein ratios throughout pregnancy. J Physiol Pharmacol 63 (3): 225-239
Berger, L. M.; Wein, S.; Blank, R.; Metges, C. C.; Wolffram, S. (2012):
Bioavailability of the flavonol quercetin in cows after intraruminal application of quercetin aglycone and rutin. J Dairy Sci 95 (9): 5047-5055
https://dx.doi.org/10.3168/jds.2012-5439
Petzke, K.-J.; Metges, C. C. (2012):
Practical recommendations for the reduction of memory effects in compound-specific 15N/14N-ratio analysis of enriched amino acids by gas chromatography/combustion/isotope ratio mass spectrometry. Rapid Commun Mass Sp 26 (2): 195-204
https://dx.doi.org/10.1002/Rcm.5319
Hammon, H. M.; Steinhoff-Wagner, J.; Schönhusen, U.; Metges, C. C.; Blum, J. W. (2012):
Energy metabolism in the newborn farm animal with emphasis on the calf: Endocrine changes and responses to milk-born and systemic hormones. DOMEST ANIM ENDOCRIN 43 (2): 171-185
https://dx.doi.org/10.1016/j.domaniend.2012.02.005
Schäff, C. T.; Albrecht, D.; Hammon, H. M.; Röntgen, M.; Metges, C. C.; Kuhla, B. (2012):
A longitudinal proteomic approach to investigate liver metabolism in periparturient dairy cows with different body fat mobilization. In: Farm Animal Proteomics : proceedings of the 3rd Managing Commitee Meeting and 2nd Meeting of the Working Groups 1,2 & 3 of COST Action FA1002 (Pedro Rodrigues, David Eckersall, Andre de Almeida, Hrsg.) Wageningen Academic Publishers, Wageningen (978-90-8686-195-8, 978-90-8686-751-6 eBook): 145-147
Tuchscherer, M.; Otten, W.; Kanitz, E.; Gräbner, M.; Tuchscherer, A.; Bellmann, O.; Rehfeldt, C.; Metges, C. C. (2012):
Effects of inadequate maternal dietary protein:carbohydrate ratios during pregnancy on offspring immunity in pigs. BMC Vet Res 8: 232-243
https://dx.doi.org/10.1186/1746-6148-8-232
Sawitzky, M.; Zeissler, A.; Langhammer, M.; Bielohuby, M.; Stock, K. F.; Hammon, H. M.; Görs, S.; Metges, C. C.; Stoehr, B. J. M.; Bidlingmaier, M.; Fromm-Dornieden, C.; Baumgartner, B. G.; Christ, B.; Brenig, B.; Binder, G.; Metzger, F.; Renne, U.; Hoeflich, A. (2012):
Phenotype selection reveals coevolution of muscle glycogen and protein and PTEN as a gate keeper for the accretion of muscle mass in adult female mice. Plos One 7 (6): 1-13
https://dx.doi.org/10.1371/journal.pone.0039711
Shi, X.; Metges, C. C.; Seyfert, H.-M. (2012):
Interaction of C/EBP-beta and NF-Y factors constrains activity levels of the nutritionally controlled promoter IA expressing the acetyl-CoA carboxylase-alpha gene in cattle. BMC Mol Biol 13: 13-21
https://dx.doi.org/10.1186/1471-2199-13-21
Laeger, T.; Pöhland, R.; Metges, C. C.; Kuhla, B. (2012):
The ketone body β-hydroxybutyric acid influences agouti-related peptide expression via AMP-activated protein kinase in hypothalamic GT1-7 cells. J Endocrinol 213 (2): 193-203
https://dx.doi.org/10.1530/Joe-11-0457
Metzler-Zebeli, B. U.; Lang, I. S.; Görs, S.; Brüssow, K.-P.; Hennig, U.; Nürnberg, G.; Rehfeldt, C.; Otten, W.; Metges, C. C. (2012):
High-protein-low-carbohydrate diet during pregnancy alters maternal plasma amino acid concentration and placental amino acid extraction but not fetal plasma amino acids in pigs. Brit J Nutr 108 (12): 2176-2189
https://dx.doi.org/10.1017/S0007114512000414
Laeger, T.; Görs, S.; Metges, C. C.; Kuhla, B. (2012):
Effect of feed restriction on metabolites in cerebrospinal fluid and plasma of dairy cows. J Dairy Sci 95 (3): 1198-1208
https://dx.doi.org/10.3168/jds.2011-4506
Metges, C. C.; Lang, I. S.; Hennig, U.; Brüssow, K.-P.; Kanitz, E.; Tuchscherer, M.; Schneider, F.; Weitzel, J. M.; Steinhoff-Ooster, A.; Sauerwein, H.; Bellmann, O.; Nürnberg, G.; Rehfeldt, C.; Otten, W. (2012):
Intrauterine growth retarded progeny of pregnant sows fed high protein:low carbohydrate diet is related to metabolic energy deficit. Plos One 7 (2): 1-10
https://dx.doi.org/10.1371/journal.pone.0031390
Rehfeldt, C.; Stabenow, B.; Pfuhl, R.; Block, J.; Nürnberg, G.; Otten, W.; Metges, C. C.; Kalbe, C. (2012):
Effects of limited and excess protein intake of pregnant gilts on carcass quality and cellular properties of skeletal muscle and subcutaneous adipose tissue in fattening pigs. J Anim Sci 90 (1): 184-196
https://dx.doi.org/10.2527/jas.2011-4234
Rehfeldt, C.; Lefaucheur, L.; Block, J.; Stabenow, B.; Pfuhl, R.; Otten, W.; Metges, C. C.; Kalbe, C. (2012):
Limited and excess protein intake of pregnant gilts differently affects body composition and cellularity of skeletal muscle and subcutaneous adipose tissue of newborn and weanling piglets. Eur J Nutr 51 (2): 151-165
https://dx.doi.org/10.1007/s00394-011-0201-8
Oster, M.; Muràni, E.; Metges, C. C.; Ponsuksili, S.; Wimmers, K. (2011):
A high protein diet during pregnancy affects hepatic gene expression of energy sensing pathways along ontogenesis in a porcine model. Plos One 6 (7): 1-12
https://dx.doi.org/10.1371/journal.pone.0021691
Metges, C. C.; Hammon, H. M.; Kuhla, B.; Röntgen, M.; Souffrant, W.-B. (2011):
International Oskar Kellner Symposium: Metabolic Flexibility in Animal and Human Nutrition, Warnemünde 9.-11.9.2011, Programme with Abstracts (Schriftenreihe / Leibniz-Institut für Nutztierbiologie, 19) : 1-143
Steinhoff-Wagner, J.; Görs, S.; Junghans, P.; Bruckmaier, R. M.; Kanitz, E.; Metges, C. C.; Hammon, H. M. (2011):
Maturation of endogenous glucose production in preterm and term calves. J Dairy Sci 94 (10): 5111-5123
https://dx.doi.org/10.3168/jds.2011-4355
Lohrenz, A.; Duske, K.; Schönhusen, U.; Losand, B.; Seyfert, H.-M.; Metges, C. C.; Hammon, H. M. (2011):
Glucose transporters and enzymes related to glucose synthesis in small intestinal mucosa of mid-lactation dairy cows fed 2 levels of starch. J Dairy Sci 94 (9): 4546-4555
https://dx.doi.org/10.3168/jds.2011-4333