Prof. Dr. rer. nat. habil. Cornelia Christiane Metges

Research Institute for Farm Animal Biology (FBN)
Head of working group Nutritional Physiology
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Research interests

  • Effect of pre- and early postnatal nutrition on growth and development in farm animals
  • Amino acid and energy metabolism
  • Nutrient and energy efficiency and emissions in farm animals

Curriculum Vitae

  • 2017: Professorship Biochemistry in Nutrition, University of Rostock
  • 2001-present: Director of Institute of Nutritional Physiology 'Oskar Kellner', Leibniz Institute for Farm Animal Biology (FBN) Dummerstorf
  • 2002-present: Lecturer in Animal Nutrition and Feed Science, University of Rostock
  • 2001: Habilitation in Nutritional Physiology (Dr. rer. nat. habil.), University of Potsdam
  • 1995-1997: Visiting Scientist, Massachusetts Institute of Technology, Clinical Research Center and Laboratory of Human Nutrition, Cambridge, USA
  • 1994-2001: Head, Working group 'Protein Metabolism', Dpt. Biochemistry and Physiology of Nutrition, German Institute of Human Nutrition (DIfE), Potsdam-Nuthetal
  • 1987-1994: Research Scientist, Chair of Nutrition Science, TU München
  • 1983-1987: Doctoral studies, TU München, Chair of General Chemistry and Biochemistry (1988; Doctorate in Agricultural Sciences; Dr. agr.), TU München
  • 1977-1983: Studies of Agricultural Sciences (Dipl.-Ing. agr.), TU München

Teaching

  • Since 2012: „Stoffwechsel-, Leistungs- und Pathophysiologie, Experimentelle Methoden in der Ernährungsphysiologie“, Master course Animal Science, University of Rostock
  • Since 2012: „Anatomisch-physiologische Grundlagen und experimentelle Methoden der Tierernährung“, Master course Animal Science, University of Rostock
  • Since 2010: „Zell- u. Molekularbiologie in der Ernährungs-forschung“ (Energy and Macronutrient metabolism), Master course Ökotrophologie, Christian-Albrechts-Universität zu Kiel
  • Since 2003: „Biochemie des Intermediärstoffwechsels“, Bachelor course in Agricultural Sciences, University of Rostock
  • 1994-2001: „Biochemie und Physiologie der Ernährung“, Master course in Nutrition Science, University of Potsdam
  • 1989-1993: „Various Aspects of Human Nutrition“ in Nutrition Science, Chair of Nutrition Science, TU München

Publications

Kuhla, B.; Metges, C. C. (2013):
Proteomic tools help understanding the metabolic adaptation to negative energy balance in dairy cows. In: Energy and protein metabolism and nutrition in sustainable animal production (EAAP Publication , 134) (James W. Oltjen et al., Hrsg.) Wageningen Academic Publ., (ISBN 978-90-8686-227-6, eISBN 978-90-8686-781-3): 213-221
Laeger, T.; Sauerwein, H.; Tuchscherer, A.; Bellmann, O.; Metges, C. C.; Kuhla, B. (2013):
Concentrations of hormones and metabolites in cerebrospinal fluid and plasma of dairy cows during the periparturient period. J Dairy Sci 96 (5): 2883-2893
https://dx.doi.org/10.3168/jds.2012-5909
Otten, W.; Kanitz, E.; Tuchscherer, M.; Gräbner, M.; Nürnberg, G.; Bellmann, O.; Hennig, U.; Rehfeldt, C.; Metges, C. C. (2013):
Effects of low and high protein:carbohydrate ratios in the diet of pregnant gilts on maternal cortisol concentrations and the adrenocortical and sympathoadrenal reactivity in their offspring. J Anim Sci 91 (6): 2680-2692
https://dx.doi.org/10.2527/jas.2012-6080
Schönhusen, U.; Junghans, P.; Flöter, A.; Steinhoff-Wagner, J.; Görs, S.; Schneider, F.; Metges, C. C.; Hammon, H. M. (2013):
First-pass uptake and oxidation of glucose by the splanchnic tissue in young goats fed soy protein-based milk diets with or without amino acid supplementation. J Dairy Sci 96 (4): 2400-2412
https://dx.doi.org/10.3168/jds.2012-5933
Derno, M.; Nürnberg, G.; Schön, P.-Ch.; Schwarm, A.; Röntgen, M.; Hammon, H. M.; Metges, C. C.; Bruckmaier, R. M.; Kuhla, B. (2013):
Short-term feed intake is regulated by macronutrient oxidation in lactating Holstein cows. J Dairy Sci 96 (2): 971-980
https://dx.doi.org/10.3168/jds.2012-5727
Altmann, S.; Muràni, E.; Schwerin, M.; Metges, C. C.; Wimmers, K.; Ponsuksili, S. (2013):
Dietary protein restriction and excess of pregnant German Landrace sows induce changes in hepatic gene expression and promoter methylation of key metabolic genes in the offspring. J Nutr Biochem 24 (2): 484-495
https://dx.doi.org/10.1016/j.jnutbio.2012.01.011
Gohlke, A.; Ingelmann, C. -J.; Nürnberg, G.; Starke, A.; Wolffram, S.; Metges, C. C. (2013):
Bioavailability of quercetin from its aglycone and its glucorhamnoside rutin in lactating dairy cows after intraduodenal administration. J Dairy Sci 96 (4): 2303-2313
https://dx.doi.org/10.3168/jds.2012-6234
Hötger, K.; Hammon, H. M.; Weber, F. M.; Görs, S.; Tröscher, A.; Bruckmaier, R. M.; Metges, C. C. (2013):
Supplementation of conjugated linoleic acid in dairy cows reduces endogenous glucose production during early lactation. J Dairy Sci 96 (4): 2258-2270
https://dx.doi.org/10.3168/jds.2012-6127
Hammon, H. M.; Steinhoff-Wagner, J.; Flor, J.; Schönhusen, U.; Metges, C. C. (2013):
Role of colostrum and colostrum components on glucose metabolism in neonatal calves. J Anim Sci 91 (2): 685-695
https://dx.doi.org/10.2527/jas.2012-5758
Blum, N. M.; Mueller, K.; Lippmann, D.; Metges, C. C.; Linn, T.; Pallauf, J.; Mueller, A. S. (2013):
Feeding of selenium alone or in combination with glucoraphanin differentially affects intestinal and hepatic antioxidant and phase II enzymes in growing rats. Biol Trace Elem Res 151 (3): 384-399
https://dx.doi.org/10.1007/s12011-012-9567-6
Döring, F.; Lüersen, K.; Schmelzer, C.; Hennig, S.; Lang, I. S.; Görs, S.; Rehfeldt, C.; Otten, W.; Metges, C. C. (2013):
Influence of maternal low protein diet during pregnancy on hepatic gene expression signature in juvenile female porcine offspring. Mol Nutr Food Res 57 (2): 277-290
https://dx.doi.org/10.1002/mnfr.201200315
Shi, X.; Metges, C. C.; Seyfert, H.-M. (2013):
Characterization of a far upstream located promoter expressing the acetyl-CoA carboxylase-alpha in the brain of cattle. Gene 515 (2): 266-271
https://dx.doi.org/10.1016/j.gene.2012.12.033
Rehfeldt, C.; Langhammer, M.; Kucia, M.; Nürnberg, G.; Metges, C. C. (2013):
Enhanced sensitivity of skeletal muscle growth in offspring of mice long-term selected for high body mass in response to a maternal high-protein/low-carbohydrate diet during lactation. Eur J Nutr 52 (3): 1201-1213
https://dx.doi.org/10.1007/s00394-012-0431-4
Kanitz, E.; Otten, W.; Tuchscherer, M.; Gräbner, M.; Brüssow, K.-P.; Rehfeldt, C.; Metges, C. C. (2012):
High and low protein: carbohydrate dietary ratios during gestation alter maternal-fetal cortisol regulation in pigs. Plos One 7 (12): 1-11
https://dx.doi.org/10.1371/journal.pone.0052748
Oster, M.; Muràni, E.; Metges, C. C.; Ponsuksili, S.; Wimmers, K. (2012):
Transcriptional response of skeletal muscle to a low-protein gestation diet in porcine offspring accumulates in growth- and cell cycle-regulating pathways. Physiol Genomics 44 (16): 811-818
https://dx.doi.org/10.1152/physiolgenomics.00050.2012
Oster, M.; Muràni, E.; Metges, C. C.; Ponsuksili, S.; Wimmers, K. (2012):
A low protein diet during pregnancy provokes a lasting shift of hepatic expression of genes related to cell cycle throughout ontogenesis in a porcine model. BMC Genomics 13 (1): 93-107
https://dx.doi.org/10.1186/1471-2164-13-93
Oster, M.; Muràni, E.; Metges, C. C.; Ponsuksili, S.; Wimmers, K. (2012):
A gestational high protein diet affects the abundance of muscle transcripts related to cell cycle regulation throughout development in porcine progeny. Plos One 7 (3): 1-9
https://dx.doi.org/10.1371/journal.pone.0034519
Altmann, S.; Muràni, E.; Schwerin, M.; Metges, C. C.; Wimmers, K.; Ponsuksili, S. (2012):
Maternal dietary protein restriction and excess affects offspring gene expression and methylation of non-SMC subunits of condensin I in liver and skeletal muscle. Epigenetics-US 7 (3): 239-252
https://dx.doi.org/10.4161/epi.7.3.19183
Altmann, S.; Muràni, E.; Schwerin, M.; Metges, C. C.; Wimmers, K.; Ponsuksili, S. (2012):
Somatic cytochrome c (CYCS) gene expression and promoter-specific DNA methylation in a porcine model of prenatal exposure to maternal dietary protein excess and restriction. Brit J Nutr 107 (6): 791-799
https://dx.doi.org/10.1017/S0007114511003667
Altmann, S.; Muràni, E.; Metges, C. C.; Schwerin, M.; Wimmers, K.; Ponsuksili, S. (2012):
Effect of gestational protein deficiency and excess on hepatic expression of genes related to cell cycle and proliferation in offspring from late gestation to finishing phase in pig. Mol Biol Rep 39 (6): 7095-7104
https://dx.doi.org/10.1007/s11033-012-1541-z