Prof. Dr. rer. nat. habil. Cornelia Christiane Metges
Research interests
- Effect of pre- and early postnatal nutrition on growth and development in farm animals
- Amino acid and energy metabolism
- Nutrient and energy efficiency and emissions in farm animals
Curriculum Vitae
- 2017: Professorship Biochemistry in Nutrition, University of Rostock
- 2001-present: Director of Institute of Nutritional Physiology 'Oskar Kellner', Leibniz Institute for Farm Animal Biology (FBN) Dummerstorf
- 2002-present: Lecturer in Animal Nutrition and Feed Science, University of Rostock
- 2001: Habilitation in Nutritional Physiology (Dr. rer. nat. habil.), University of Potsdam
- 1995-1997: Visiting Scientist, Massachusetts Institute of Technology, Clinical Research Center and Laboratory of Human Nutrition, Cambridge, USA
- 1994-2001: Head, Working group 'Protein Metabolism', Dpt. Biochemistry and Physiology of Nutrition, German Institute of Human Nutrition (DIfE), Potsdam-Nuthetal
- 1987-1994: Research Scientist, Chair of Nutrition Science, TU München
- 1983-1987: Doctoral studies, TU München, Chair of General Chemistry and Biochemistry (1988; Doctorate in Agricultural Sciences; Dr. agr.), TU München
- 1977-1983: Studies of Agricultural Sciences (Dipl.-Ing. agr.), TU München
Teaching
- Since 2012: „Stoffwechsel-, Leistungs- und Pathophysiologie, Experimentelle Methoden in der Ernährungsphysiologie“, Master course Animal Science, University of Rostock
- Since 2012: „Anatomisch-physiologische Grundlagen und experimentelle Methoden der Tierernährung“, Master course Animal Science, University of Rostock
- Since 2010: „Zell- u. Molekularbiologie in der Ernährungs-forschung“ (Energy and Macronutrient metabolism), Master course Ökotrophologie, Christian-Albrechts-Universität zu Kiel
- Since 2003: „Biochemie des Intermediärstoffwechsels“, Bachelor course in Agricultural Sciences, University of Rostock
- 1994-2001: „Biochemie und Physiologie der Ernährung“, Master course in Nutrition Science, University of Potsdam
- 1989-1993: „Various Aspects of Human Nutrition“ in Nutrition Science, Chair of Nutrition Science, TU München
Publications
Metges, C. C. (2013):
Einfluss der mütterlichen Ernährung auf Leistungs- und physiologische Parameter der Nachkommen: Pränatale Programmierung beim Schwein. In: 12. Tagung Schweine- und Geflügelernährung, 12.-14. November 2013, Lutherstadt Wittenberg (A. Zeyner et al., Hrsg.) Institut für Agrar- und Ernährungswissenschaften, Universität Halle-Wittenberg, (ISBN 978-3-86829-575-7): 124-130
Metges, C. C.; Hammon, H. M.; Derno, M.; Weber, F. M.; Kuhla, B. (2013):
Beeinflussung des Erhaltungs- und Leistungsbedarfs durch physiologische Faktoren als Grundlage einer effizienten Milchproduktion. Schriftenreihe / Leibniz-Institut für Nutztierbiol 22: 9-16
Nebendahl, C.; Krüger, R.; Görs, S.; Albrecht, E.; Martens, K.; Hennig, S.; Storm, N.; Höppner, Wolfgang; Pfuhl, R.; Metzler-Zebeli, B. U.; Hammon, H. M.; Metges, C. C. (2013):
Effects on transcriptional regulation and lipid droplet characteristics in the liver of female juvenile pigs after early postnatal feed restriction and refeeding are dependent on birth weight. Plos One 8 (11): 1-19
https://dx.doi.org/10.1371/journal.pone.0076705
Gohlke, A.; Ingelmann, C. -J.; Nürnberg, G.; Weitzel, J. M.; Hammon, H. M.; Görs, S.; Starke, A.; Wolffram, S.; Metges, C. C. (2013):
Influence of 4-week intraduodenal supplementation of quercetin on performance, glucose metabolism, and mRNA abundance of genes related to glucose metabolism and antioxidative status in dairy cows. J Dairy Sci 96 (11): 6986-7000
https://dx.doi.org/10.3168/jds.2013-6852
Hötger, K.; Hammon, H. M.; Metges, C. C. (2013):
CLAs ermöglichen effizientere Produktion. ELITE (6): 42-43
Kuhla, B.; Metges, C. C. (2013):
Proteomic tools help understanding the metabolic adaptation to negative energy balance in dairy cows. In: Energy and protein metabolism and nutrition in sustainable animal production (EAAP Publication , 134) (James W. Oltjen et al., Hrsg.) Wageningen Academic Publ., (ISBN 978-90-8686-227-6, eISBN 978-90-8686-781-3): 213-221
Laeger, T.; Sauerwein, H.; Tuchscherer, A.; Bellmann, O.; Metges, C. C.; Kuhla, B. (2013):
Concentrations of hormones and metabolites in cerebrospinal fluid and plasma of dairy cows during the periparturient period. J Dairy Sci 96 (5): 2883-2893
https://dx.doi.org/10.3168/jds.2012-5909
Otten, W.; Kanitz, E.; Tuchscherer, M.; Gräbner, M.; Nürnberg, G.; Bellmann, O.; Hennig, U.; Rehfeldt, C.; Metges, C. C. (2013):
Effects of low and high protein:carbohydrate ratios in the diet of pregnant gilts on maternal cortisol concentrations and the adrenocortical and sympathoadrenal reactivity in their offspring. J Anim Sci 91 (6): 2680-2692
https://dx.doi.org/10.2527/jas.2012-6080
Schönhusen, U.; Junghans, P.; Flöter, A.; Steinhoff-Wagner, J.; Görs, S.; Schneider, F.; Metges, C. C.; Hammon, H. M. (2013):
First-pass uptake and oxidation of glucose by the splanchnic tissue in young goats fed soy protein-based milk diets with or without amino acid supplementation. J Dairy Sci 96 (4): 2400-2412
https://dx.doi.org/10.3168/jds.2012-5933
Derno, M.; Nürnberg, G.; Schön, P.-Ch.; Schwarm, A.; Röntgen, M.; Hammon, H. M.; Metges, C. C.; Bruckmaier, R. M.; Kuhla, B. (2013):
Short-term feed intake is regulated by macronutrient oxidation in lactating Holstein cows. J Dairy Sci 96 (2): 971-980
https://dx.doi.org/10.3168/jds.2012-5727
Altmann, S.; Muràni, E.; Schwerin, M.; Metges, C. C.; Wimmers, K.; Ponsuksili, S. (2013):
Dietary protein restriction and excess of pregnant German Landrace sows induce changes in hepatic gene expression and promoter methylation of key metabolic genes in the offspring. J Nutr Biochem 24 (2): 484-495
https://dx.doi.org/10.1016/j.jnutbio.2012.01.011
Gohlke, A.; Ingelmann, C. -J.; Nürnberg, G.; Starke, A.; Wolffram, S.; Metges, C. C. (2013):
Bioavailability of quercetin from its aglycone and its glucorhamnoside rutin in lactating dairy cows after intraduodenal administration. J Dairy Sci 96 (4): 2303-2313
https://dx.doi.org/10.3168/jds.2012-6234
Hötger, K.; Hammon, H. M.; Weber, F. M.; Görs, S.; Tröscher, A.; Bruckmaier, R. M.; Metges, C. C. (2013):
Supplementation of conjugated linoleic acid in dairy cows reduces endogenous glucose production during early lactation. J Dairy Sci 96 (4): 2258-2270
https://dx.doi.org/10.3168/jds.2012-6127
Hammon, H. M.; Steinhoff-Wagner, J.; Flor, J.; Schönhusen, U.; Metges, C. C. (2013):
Role of colostrum and colostrum components on glucose metabolism in neonatal calves. J Anim Sci 91 (2): 685-695
https://dx.doi.org/10.2527/jas.2012-5758
Blum, N. M.; Mueller, K.; Lippmann, D.; Metges, C. C.; Linn, T.; Pallauf, J.; Mueller, A. S. (2013):
Feeding of selenium alone or in combination with glucoraphanin differentially affects intestinal and hepatic antioxidant and phase II enzymes in growing rats. Biol Trace Elem Res 151 (3): 384-399
https://dx.doi.org/10.1007/s12011-012-9567-6
Döring, F.; Lüersen, K.; Schmelzer, C.; Hennig, S.; Lang, I. S.; Görs, S.; Rehfeldt, C.; Otten, W.; Metges, C. C. (2013):
Influence of maternal low protein diet during pregnancy on hepatic gene expression signature in juvenile female porcine offspring. Mol Nutr Food Res 57 (2): 277-290
https://dx.doi.org/10.1002/mnfr.201200315
Shi, X.; Metges, C. C.; Seyfert, H.-M. (2013):
Characterization of a far upstream located promoter expressing the acetyl-CoA carboxylase-alpha in the brain of cattle. Gene 515 (2): 266-271
https://dx.doi.org/10.1016/j.gene.2012.12.033
Rehfeldt, C.; Langhammer, M.; Kucia, M.; Nürnberg, G.; Metges, C. C. (2013):
Enhanced sensitivity of skeletal muscle growth in offspring of mice long-term selected for high body mass in response to a maternal high-protein/low-carbohydrate diet during lactation. Eur J Nutr 52 (3): 1201-1213
https://dx.doi.org/10.1007/s00394-012-0431-4
Kanitz, E.; Otten, W.; Tuchscherer, M.; Gräbner, M.; Brüssow, K.-P.; Rehfeldt, C.; Metges, C. C. (2012):
High and low protein: carbohydrate dietary ratios during gestation alter maternal-fetal cortisol regulation in pigs. Plos One 7 (12): 1-11
https://dx.doi.org/10.1371/journal.pone.0052748
Oster, M.; Muràni, E.; Metges, C. C.; Ponsuksili, S.; Wimmers, K. (2012):
Transcriptional response of skeletal muscle to a low-protein gestation diet in porcine offspring accumulates in growth- and cell cycle-regulating pathways. Physiol Genomics 44 (16): 811-818
https://dx.doi.org/10.1152/physiolgenomics.00050.2012