Dr. rer. nat. Christina Walz

+49 38208 68-702
Research Institute for Farm Animal Biology (FBN)
Institute of Genome Biology
Signal transduction Unit
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Publications

Hoeflich, A.; Fitzner, B.; Walz, C.; Hecker, M.; Tuchscherer, A.; Brenmoehl, J.; Zettl, U. K. (2021):
Reduced Fragmentation of IGFBP-2 and IGFBP-3 as a Potential Mechanism for Decreased Ratio of IGF-II to IGFBPs in Cerebrospinal Fluid in Response to Repeated Intrathecal Administration of Triamcinolone Acetonide in Patients With Multiple Sclerosis. Front Endocrinol 11: 565557, 1-10
https://doi.org/10.3389/fendo.2020.565557
Walz, C.; Brenmoehl, J.; Trakooljul, N.; Noce, A.; Caffier, C.; Ohde, D.; Langhammer, M.; Wimmers, K.; Ponsuksili, S.; Hoeflich, A. (2021):
Control of Protein and Energy Metabolism in the Pituitary Gland in Response to Three-Week Running Training in Adult Male Mice . Cells-Basel 10 (4): 736, 1-20
https://doi.org/10.3390/cells10040736
Walz, M.; Höflich, C.; Walz, C.; Ohde, D.; Brenmoehl, J.; Sawitzky, M.; Vernunft, A.; Zettl, U. K.; Holtze, S.; Hildebrandt, T. B.; Wolf, E.; Hoeflich, A. (2021):
Development of a Sensitive Bioassay for the Analysis of IGF-Related Activation of AKT/mTOR Signaling in Biological Matrices. Cells-Basel 10 (3): 482, 1-19
https://doi.org/10.3390/cells10030482
Brenmoehl, J.; Walz, C.; Caffier, C.; Brosig, E.; Walz, C.; Ohde, D.; Trakooljul, N.; Langhammer, M.; Ponsuksili, S.; Wimmers, K.; Zettl, U. K.; Höflich, A. (2021):
Central Suppression of the GH/IGF Axis and Abrogation of Exercise-Related mTORC1/2 Activation in the Muscle of Phenotype-Selected Male Marathon Mice (DUhTP). Cells-Basel 10 (12): 3418, 1-19
https://doi.org/10.3390/cells10123418
Ohde, D.; Walz, M.; Walz, C.; Noce, A.; Brenmoehl, J.; Langhammer, M.; Hoeflich, A. (2020):
Sex-specific control of muscle mass: elevated IGFBP proteolysis and reductions of IGF-1 levels are associated with substantial loss of carcass weight in male DU6PxIGFBP-2 transgenic mice. Cells-Basel 9 (10): 2174, 1-17
https://doi.org/10.3390/cells9102174
Hoeflich, A.; Fitzner, B.; Walz, C.; Hecker, M.; Tuchscherer, A.; Bastian, M.; Brenmoehl, J.; Schröder, S.; Willenberg, H.S.; Reincke, M. (2020):
Systemic effects by intrathecal administration of triamcinolone acetonide in patients with multiple sclerosis. Front Endocrinol 11: 574, 1-8
https://doi.org/10.3389/fendo.2020.00574
Brenmoehl, J.; Ohde, D.; Walz, C.; Langhammer, M.; Schultz, J.; Hoeflich, A. (2020):
Analysis of activity-dependent energy metabolism in mice reveals regulation of mitochondrial fission and fusion mRNA by voluntary physical exercise in subcutaneous fat from male marathon mice (DUhTP). Cells-Basel 9: 2697, 1-20
https://doi.org/10.3390/cells9122697
Brenmoehl, J.; Walz, C.; Spitschak, M.; Wirthgen, E.; Walz, M.; Langhammer, M.; Tuchscherer, A.; Naumann, R.; Höflich, A. (2018):
Partial phenotype conversion and differential trait response to conditions of husbandry in mice. J Comp Physiol B 188 (3): 527-539
https://doi.org/10.1007/s00360-017-1138-x
Wirthgen, E.; Goumon, S.; Kunze, M.; Walz, C.; Spitschak, M.; Tuchscherer, A.; Brown, J.; Höflich, C.; Faucitano, L.; Hoeflich, A. (2018):
Effects of transport duration and environmental conditions in winter or summer on the concentrations of insulin-like growth factors and insulin-like growth factor-binding proteins in the plasma of market-weight pigs. Front Endocrinol 9: 36, 1-10
https://doi.org/10.3389/fendo.2018.00036
Brenmoehl, J.; Ohde, D.; Albrecht, E.; Walz, C.; Tuchscherer, A.; Hoeflich, A. (2017):
Browning of subcutaneous fat and higher surface temperature in response to phenotype selection for advanced endurance exercise performance in male DUhTP mice. J Comp Physiol B 187 (2): 361-373
https://dx.doi.org/10.1007/s00360-016-1036-7
Wirthgen, E.; Kunze, M.; Goumon, S.; Walz, C.; Höflich, C.; Spitschak, M.; Brenmoehl, J.; Kanitz, E.; Tuchscherer, M.; Otten, W.; Gimsa, U.; Schön, P.- C.; Manteuffel, C.; Tuchscherer, A.; Pfuhl, R.; Metges, C. C.; Stabenow, B.; Erdmann, S.; Schluricke, K.; Faucitano, L.; Hoeflich, A. (2017):
Interference of stress with the somatotropic axis in pigs - lights on new biomarkers. Sci Rep-UK 7: 12055, 1-13
https://dx.doi.org/10.1038/s41598-017-11521-5
Schindler, N.; Mayer, J.; Saenger, S.; Gimsa, U.; Walz, C.; Ohde, D.; Wirthgen, E.; Tuchscherer, A.; Russo, V. C.; Frank, M.; Kirschstein, T.; Metzger, F.; Hoeflich, A. (2017):
Phenotype analysis of male transgenic mice overexpressing mutant IGFBP-2 lacking the Cardin-Weintraub sequence motif: reduced expression of synaptic markers and myelin basic protein in the brain and a lower degree of anxiety-like behaviour. Growth Horm IGF Res 33: 1-8
https://dx.doi.org/10.1016/j.ghir.2016.11.003
Ohde, D.; Brenmoehl, J.; Walz, C.; Tuchscherer, A.; Wirthgen, E.; Hoeflich, A. (2016):
Comparative analysis of hepatic miRNA levels in male marathon mice reveals a link between obesity and endurance exercise capacities. J Comp Physiol B 186 (8): 1067-1078
https://dx.doi.org/10.1007/s00360-016-1006-0
Ohde, D.; Moeller, M.; Brenmoehl, J.; Walz, C.; Ponsuksili, S.; Schwerin, M.; Fuellen, G.; Hoeflich, A. (2016):
Advanced running performance by genetic predisposition in male Dummerstorf marathon mice (DUhTP) reveals higher sterol regulatory element-binding protein (SREBP) related mRNA expression in the liver and higher serum levels of progesterone. Plos One 11 (1): e0146748, 1-16
https://dx.doi.org/10.1371/journal.pone.0146748
Reyer, A.; Schindler, N.; Ohde, D.; Walz, C.; Kunze, M.; Tuchscherer, A.; Wirthgen, E.; Brenmoehl, J.; Hoeflich, A. (2015):
The RGD sequence present in IGFBP-2 is required for reduced glucose clearance after oral glucose administration in female transgenic mice. Am J Physiol-Endoc M 309 (4): 409-417
https://dx.doi.org/10.1152/ajpendo.00168.2015
Ohde, D.; Brenmoehl, J.; Walz, C.; Höflich, A. (2015):
Identification and characterization of microRNAs relevant for energy metabolism in Dummerstorf "marathon mice" DUhTP. Schriftenreihe / Leibniz-Institut für Nutztierbiol 24: 33-36"
Brenmoehl, J.; Ohde, D.; Walz, C.; Tuchscherer, A.; Schultz, J.; Rieder, F.; Hoeflich, A. (2015):
Dynamics of fat mass in DUhTP mice selected for running performance - fat mobilization in a walk. Obesity Facts 8 (6): 373-385
https://dx.doi.org/10.1159/000442399
Kunze, M.; Wirthgen, E.; Walz, C.; Spitschak, M.; Brenmoehl, J.; Vanselow, J.; Schwerin, M.; Wimmers, K.; Hoeflich, A. (2015):
Bioanalytical validation for simultaneous quantification of non-aromatic steroids in follicular fluid from cattle via ESI-LC-MS/MS. J Chromatogr B 1007: 132-139
https://dx.doi.org/10.1016/j.jchromb.2015.10.010
Brenmoehl, J.; Walz, C.; Renne, U.; Ponsuksili, S.; Wolf, C.; Langhammer, M.; Schwerin, M.; Hoeflich, A. (2013):
Metabolic adaptations in the liver of born long-distance running mice. Med Sci Sport Exer 45 (5): 841-850
https://dx.doi.org/10.1249/MSS.0b013e31827e0fca
Renne, U.; Langhammer, M.; Brenmoehl, J.; Walz, C.; Zeissler, A.; Tuchscherer, A.; Piechotta, M.; Wiesner, R. J.; Bielohuby, M.; Hoeflich, A. (2013):
Lifelong obesity in a polygenic mouse model prevents age- and diet-induced glucose intolerance - obesity is no road to late-onset diabetes in mice. Plos One 8 (11): e79788, 1-8
https://dx.doi.org/10.1371/journal.pone.0079788