Prof. Dr. med. vet. Christa Kühn

+49 38208 68-702
Research Institute for Farm Animal Biology (FBN)
Institute of Genome Biology
Genome Physiology Unit
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Research interests

  • Genome analysis
  • Animal breeding and genetics
  • Molecular genetics
  • Disease resistance

Curriculum Vitae

  • 2018-present: Head of Institute of Genome Biology
  • 2014-present: Professor for Genetics of Disease Resistance at the Faculty of Agricultural and Environmental Science at the University Rostock
  • 2013-present: Director of the Genome Physiology Unit, Leibniz Institute for Farm Animal Biology (FBN) Dummerstorf, Institute of Genome Biology
  • 2013: Call for Professor for Genetics of Disease Resistance at the University of Rostock
  • 2012: Vice Chair Research and Development at the Leibniz Institute for Farm Animal Biology (FBN) Dummerstorf
  • 2011: Call for Professor for Animal genetics and pathogenetics at the Justus-Liebig-Universität Gießen
  • 2008: Authorization to provide post-gradual veterinary qualification in „Molecular Biology“
  • 2005: Habilitation at the Faculty for Agricultural and Environmental Sciences of the University of Rostock
  • 2004-2012: Team leader „QTL regions“, Leibniz Institute for Farm Animal Biology (FBN) Dummerstorf, Institute of Molecular Biology
  • 1992-present: Scientist in the Institute of Molecular Biology at the Leibniz Institute for Farm Animal Biology (FBN) Dummerstorf
  • 1991-1992: Veterinary practitioner with focus on farm animals (cattle, pig, sheep, horse) in the veterinary centre M. Schibalski, Quakenbrück, Germany
  • 1990: Post-doc at the Veterinary University Hanover
  • 1989: Promotion to Dr. med. vet. at the Veterinary University Hannover and approbation
  • 1987: Final Veterinary State Examination at the Veterinary University Hanover

Professional Activities

  • 2011-present: Member of the Editorial Board for Animal Genetics
  • 2010-present: Editor for the Journal of Dairy Science
  • 2011-present: Treasurer of the Gesellschaft für Tierzuchtwissenschaften (GfT)
  • 2009-present: Associate Editor for Genetics, Selection, Evolution
  • 2006-2011: Editor for ANIMAL

Teaching

  • since 2004: Teaching at the Faculty of Mathematics and Natural Science at the University Rostock within Diplome and Master courses for Biology and for Diversity and Evolution
  • since 2003: Teaching at the Faculty of Agricultural and Environmental Science at the University Rostock within Bachelor and Master courses in Agricultural Science, Agricultural Ecology and Animal Science

Publications

Kühn, Ch.; Thaller, G. (2005):
Nachweis von pleiotropen Effekten und multiplen Allelen für das bovine acyl-CoA:diacylglycerol acyltransferase (DGAT1) Gen. Schriftenreihe / Forschungsinstitut für die Biolog 15: 35-42
Kühn, Ch.; Weikard, R.; Laurent, P.; Goldammer, T. (2005):
Assignment of the fibroblast growth factor 10 (FGF10) gene to bovine chromosome 20q16→q17 by fluorescence in situ hybridization and somatic cell panel analysis. Cytogenet Genome Res 109 (4): 533D
https://dx.doi.org/10.1159/000084218
Schwerin, M.; Goldammer, T.; Kühn, Ch.; Walz, C.; Ponsuksili, S. (2005):
Identification of genetic variants in differentially expressed sequences in cattle of different metabolic type - potential genetic markers of nutrient utilization. Arch Tierzucht 48: 324-333
Ponsuksili, S.; Brunner, R. M.; Goldammer, T.; Kühn, Ch.; Walz, C.; Chomdej, S.; Tesfaye, D.; Schellander, K.; Wimmers, K.; Schwerin, M. (2005):
Bovine NALP5, NALP8, and NALP9 Genes: Assignment to a QTL Region and the Expression in Adult Tissues, Oocytes, and Preimplantation Embryos. Biol Reprod 74 (3): 577-584
https://dx.doi.org/10.1095/biolreprod.105.045096
Schwerin, M.; Kühn, Ch.; Brunner, R. M.; Goldammer, T.; Bennewitz, J.; Reinsch, N.; Xu, T.; Thomsen, H.; Looft, C.; Kalm, E. (2004):
QTL mapping and mining for functional candidate genes affecting health - the German ADR QTL Dairy Cattle Project. Animal Sci Papers and Reports 22 (1): 95-100
Bennewitz, J.; Reinsch, N.; Paul, S.; Looft, C.; Kaupe, B.; Weimann, C; Erhardt, G.; Thaller, G.; Kühn, Ch.; Schwerin, M. (2004):
The DGAT1 K232A mutation is not solely responsible for the milk production quantitative trait locus on the bovine chromosome 14. J Dairy Sci 87 (2): 431-442
https://dx.doi.org/10.3168/jds.S0022-0302(04)73182-3
Kühn, Ch.; Thaller, G.; Winter, A.; Bininda-Emonds, O.R.P.; Kaupe, B.; Erhardt, G.; Bennewitz, J.; Schwerin, M.; Fries, R. (2004):
Evidence for multiple alleles at the DGAT1 locus better explains a quantitative trait locus with major effect on milk fat content in cattle . Genetics 167 (4): 1873-1881
https://dx.doi.org/10.1534/genetics.103.022749
Freyer, G.; Sorensen, P.; Kühn, Ch.; Weikard, R. (2004):
Investigations in the character of QTL affecting negatively correlated milk traits. J Anim Breed Genet 121 (1): 40-51
https://dx.doi.org/10.1046/j.0931-2668.2003.00407.x
Goldammer, T.; Kata, S.R.; Brunner, R. M.; Kühn, Ch.; Weikard, R.; Womack, J.E.; Schwerin, M. (2004):
High-resolution comparative mapping between human chromosomes 4 and 8 and bovine chromosome 27 provides genes and segments serving as positional candidates for udder health in cattle. Genomics 84 (4): 696-706
https://dx.doi.org/10.1016/j.ygeno.2003.12.003
Bennewitz, J.; Reinsch, N.; Guiard, V.; Fritz, S.; Thomsen, H.; Looft, C.; Kühn, Ch.; Schwerin, M.; Weimann, C; Erhardt, G.; Reinhardt, F.; Reents, R.; Boichard, D.; Kalm, E. (2004):
Multiple quantitative trait loci mapping with cofactors and application of alternative variants of the false discovery rate in an enlarged granddaughter design. Genetics 168 (2): 1019-1027
https://dx.doi.org/10.1534/genetics.104.030296
Zsolnai, A.; Anton, I.; Kühn, Ch.; Fésüs, L. (2003):
Detection of single-nucleotide polymorphisms coding for three ovine prion protein variants by primer extension assay and capillary electrophoresis. Electrophoresis 24 (4): 634-638
https://dx.doi.org/10.1002/elps.200390074
Kühn, Ch.; Bennewitz, J.; Reinsch, N.; Xu, T.; Thomsen, H.; Looft, C.; Brockmann, G.; Schwerin, M.; Kalm, E.; Weimann, C.; Hiendleder, S.; Erhardt, G.; Medjugorac, I.; Förster, M.; Brenig, B.; Reinhardt, F.; Reents, R.; Russ, I.; Averdunk, G.; Blümel, J. (2003):
Quantitative trait loci mapping of functional traits in the German holstein cattle population. J Dairy Sci 86: 360-368
https://dx.doi.org/10.3168/jds.S0022-0302(03)73614-5
Brunner, R. M.; Sanftleben, H.; Goldammer, T.; Kühn, Ch.; Weikard, R.; Kata, S.R.; Womack, J.E.; Schwerin, M. (2003):
The telomeric region of BTA18 containing a potential QTL region for health in cattle exhibits high similarity to the HSA19q region in humans. Genomics 81 (3): 270-278
https://dx.doi.org/10.1016/S0888-7543(03)00019-3
Bennewitz, J.; Reinsch, N.; Schwerin, M.; Kühn, Ch.; Brockmann, G.; Grohs, C.; Levéziel, H.; Malafosse, A.; Thomsen, H.; Xu, T.; Looft, C.; Hiendleder, S.; Erhardt, G.; Medjugorac, I.; Russ, I.; Förster, M.; Brenig, B.; Reinhardt, F.; Reents, R.; Averdunk, G.; Blümel, J.; Boichard, D.; Kalm, E.; Weimann, C. (2003):
Combined analysis of data from two granddaughter designs: A simple strategy for QTL confirmation and increasing experimental power in dairy cattle. Genet Sel Evol 35 (3): 319-338
https://dx.doi.org/10.1051/gse:2003011
Freyer, G.; Sorensen, P.; Kühn, Ch.; Weikard, R.; Hoeschele, I. (2003):
Search for pleiotropic QTL on chromosome BTA6 affecting yield traits of milk production. J Dairy Sci 86 (3): 999-1008
https://dx.doi.org/10.3168/jds.S0022-0302(03)73683-2
Thaller, G.; Kühn, Ch.; Winter, A.; Ewald, D.; Bellmann, O.; Wegner, J.; Zühlke, H.; Fries, R. (2003):
DGAT1, a new positional and functional candidate gene for intramuscular fat deposition in cattle. Anim Genet 34 (5): 354-357
https://dx.doi.org/10.1046/j.1365-2052.2003.01011.x
Freyer, G.; Kühn, Ch.; Weikard, R. (2003):
Comparison of different statistical-genetic approaches of QTL detection by Evaluating results from a real dairy cattle data set. Arch Tierzucht 46 (5): 413-423
Hiendleder, S.; Thomsen, H.; Reinsch, N.; Brockmann, G.; Kühn, Ch.; Schwerin, M.; Bennewitz, J.; Leyhe-Horn, B.; Looft, C.; Xu, T.; Medjugorac, I.; Russ, I.; Blümel, J.; Brenig, B.; Reinhardt, F.; Reents, R.; Averdunk, G.; Förster, M.; Kalm, E.; Erhardt, G. (2003):
Mapping of QTL for Body Conformation and Behavior in Cattle. J Hered 94 (6): 496-506
https://dx.doi.org/10.1093/jhered/esg090
Freyer, G.; Kühn, Ch.; Weikard, R.; Zhang, Q.; Mayer, M.; Hoeschele, I. (2002):
Multiple QTL on chromosome six in dairy cattle affecting yield and content traits. J Anim Breed Genet 119 (2): 69-82
https://dx.doi.org/10.1046/j.1439-0388.2002.00322.x
Weikard, R.; Kühn, Ch.; Goldammer, T.; Laurent, P.; Womack, J.E.; Schwerin, M. (2002):
Targeted construction of a high-resolution, integrated, comprehensive, and comparative map for a region specific to bovine chromosome 6 based on radiation hybrid mapping. Genomics 79 (6): 768-776
https://dx.doi.org/10.1006/geno.2002.6778