PD Dr. rer. nat. habil. Björn Kuhla
Research Institute for Farm Animal Biology (FBN)
Head of working group Nutritional Biochemistry
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Head of working group Nutritional Biochemistry
Wilhelm-Stahl-Allee 2
18196 Dummerstorf
Research interests
- Neuronal and metabolic control of feed intake
- Links between feed efficiency, diet and methane production
- Metabolic adaptation to environmental heat
Curriculum Vitae
- 2013-present: Director of 'Fuel Sensing Unit', Leibniz Institute for Farm Animal Biology (FBN) Dummerstorf, Institute of Nutritional Physiology "Oskar Kellner"
- 2009-2012: Leader of Junior Research Group „Feed Intake Regulation“, Leibniz Institute for Farm Animal Biology (FBN) Dummerstorf
- 2006-present: Scientist at the Institute of Nutritional Physiology “Oskar Kellner”, Leibniz Institute for Farm Animal Biology (FBN) Dummerstorf
- Habilitation and venia legendi in Biochemistry
- Post Doc at the Agricultural Research Centre of the Bayer AG Monheim, University of Leipzig, and Case Western Reserve University, Cleveland
- Diploma and Doctoral Degree in Chemistry
- Secondary education and apprenticeship for animal production
Teaching
- Anatomic-Physiological Basics and Methods in Animal Nutrition
- Metabolism and performance physiology
- Practical Course “Isolation of RNA from plant leaves”
Publications
Börner, S.; Albrecht, E.; Schäff, C. T.; Hacke, S.; Kautzsch, U.; Derno, M.; Hammon, H. M.; Röntgen, M.; Sauerwein, H.; Kuhla, B. (2013):
Reduced AgRP activation in the hypothalamus of cows with high extent of fat mobilization after parturition. Gen Comp Endocr 193: 167-177
https://dx.doi.org/10.1016/j.ygcen.2013.08.002
Derno, M.; Nürnberg, G.; Schön, P.-Ch.; Schwarm, A.; Röntgen, M.; Hammon, H. M.; Metges, C. C.; Bruckmaier, R. M.; Kuhla, B. (2013):
Short-term feed intake is regulated by macronutrient oxidation in lactating Holstein cows. J Dairy Sci 96 (2): 971-980
https://dx.doi.org/10.3168/jds.2012-5727
Börner, S.; Derno, M.; Hacke, S.; Kautzsch, U.; Schäff, C. T.; ThanThan, S.; Kuwayama, H.; Hammon, H. M.; Röntgen, M.; Weikard, R.; Kühn, C.; Tuchscherer, A.; Kuhla, B. (2013):
Plasma ghrelin is positively associated with body fat, liver fat and milk fat content, but not with feed intake of dairy cows after parturition. J Endocrinol 216 (2): 217-229
https://dx.doi.org/10.1530/Joe-12-0384
Kuhla, B. (2012):
Die Rolle von Carbonylen bei glycierungsabhängigen neurodegenerativen Prozessen und bei der neuronalen Kontrolle der Nahrungsaufnahme. Habilitationsschrift, Universität Rostock: 1-216
Schäff, C. T.; Albrecht, D.; Hammon, H. M.; Röntgen, M.; Metges, C. C.; Kuhla, B. (2012):
A longitudinal proteomic approach to investigate liver metabolism in periparturient dairy cows with different body fat mobilization. In: Farm Animal Proteomics : proceedings of the 3rd Managing Commitee Meeting and 2nd Meeting of the Working Groups 1,2 & 3 of COST Action FA1002 (Pedro Rodrigues, David Eckersall, Andre de Almeida, Hrsg.) Wageningen Academic Publishers, Wageningen (978-90-8686-195-8, 978-90-8686-751-6 eBook): 145-147
Schäff, C. T.; Boener, S.; Hacke, S.; Kautsch, U.; Albrecht, D.; Hammon, H. M.; Röntgen, M.; Kuhla, B. (2012):
Increased Anaplerosis, TCA Cycling, and Oxidative Phosphorylation in the Liver of Dairy Cows with Intensive Body Fat Mobilization during Early Lactation. J Proteome Res 11 (11): 5503-5514
https://dx.doi.org/10.1021/Pr300732n
Laeger, T.; Pöhland, R.; Metges, C. C.; Kuhla, B. (2012):
The ketone body β-hydroxybutyric acid influences agouti-related peptide expression via AMP-activated protein kinase in hypothalamic GT1-7 cells. J Endocrinol 213 (2): 193-203
https://dx.doi.org/10.1530/Joe-11-0457
Laeger, T.; Hammon, H. M.; Kuhla, B. (2012):
Beta-hydroxybutyric acid/glucose ratio dependent orexigenic signaling in hypothalamic GT1-7 cells. Proc. Soc. Nutr. Physiol. 21: 52-52
Laeger, T.; Görs, S.; Metges, C. C.; Kuhla, B. (2012):
Effect of feed restriction on metabolites in cerebrospinal fluid and plasma of dairy cows. J Dairy Sci 95 (3): 1198-1208
https://dx.doi.org/10.3168/jds.2011-4506
Metges, C. C.; Hammon, H. M.; Kuhla, B.; Röntgen, M.; Souffrant, W.-B. (2011):
International Oskar Kellner Symposium: Metabolic Flexibility in Animal and Human Nutrition, Warnemünde 9.-11.9.2011, Programme with Abstracts (Schriftenreihe / Leibniz-Institut für Nutztierbiologie, 19) : 1-143
Kuhla, B.; Görs, S.; Metges, C. C. (2011):
Hypothalamic orexin A expression and the involvement of AMPK and PPAR-gama signalling in energy restricted dairy cows. Arch Tierzucht 54 (6): 567-579
Niemann, H.; Kuhla, B.; Flachowsky, G. (2011):
Perspectives for feed-efficient animal production. J Anim Sci 89 (12): 4344-4363
https://dx.doi.org/10.2527/jas.2011-4235
Kuhla, B.; Nürnberg, G.; Albrecht, D.; Görs, S.; Hammon, H. M.; Metges, C. C. (2011):
Involvement of skeletal muscle protein, glycogen and fat metabolism in the adaptation on early lactation of dairy cows. J Proteome Res 10 (9): 4252-4262
https://dx.doi.org/10.1021/Pr200425h
Laeger, T.; Kuhla, B. (2011):
Feed restriction in dairy cows affects resistin levels in plasma and cerebrospinal fluid. Proc. Soc. Nutr. Physiol. 20: 141
Kuhla, B.; Görs, S.; Metges, C. C. (2011):
Changes of muscle amino acids, glycogen, and fat concentrations of dairy cows during the periparturient period . Proc. Soc. Nutr. Physiol. 20: 38
Kuhla, B.; Albrecht, D.; Bruckmaier, R. M.; Viergutz, T.; Nürnberg, G.; Metges, C. C. (2010):
Proteome and radioimmunoassay analyses of pituitary hormones and proteins in response to feed restriction of dairy cows. PROTEOMICS 10 (24): 4491-4500
https://dx.doi.org/10.1002/pmic.201000383
Kuhla, B.; Bellmann, O.; Metges, C. C. (2010):
Technical note: An apparatus for catheterization of the lateral brain ventricle in Holstein cows. J Dairy Sci 93 (12): 5837-5841
https://dx.doi.org/10.3168/jds.2010-3431
Derno, M.; Schwarm, A.; Kuhla, B.; Schweigel, M. (2010):
Phenotypic variation of energy intake and heat production in lactating cows fed ad libitum and restricted. In: Energy and protein metabolism and nutrition (G. Matteo Crovetto, Hrsg.) Wageningen Academic Publishers, Wageningen (978-90-8686-153-8): 319-320
Kuhla, B.; Kucia, M.; Görs, S.; Albrecht, D.; Langhammer, M.; Kuhla, B.; Metges, C. C. (2010):
Effect of a high-protein diet on food intake and liver metabolism during pregnancy, lactation and after weaning in mice. PROTEOMICS 10 (14): 2573-2588
https://dx.doi.org/10.1002/pmic.200900789
Laeger, T.; Metges, C. C.; Kuhla, B. (2010):
Role of β-hydroxybutyric acid in the central regulation of energy balance. Appetite 54 (3): 450-455
https://dx.doi.org/10.1016/j.appet.2010.04.005