PD Dr. rer. nat. habil. Björn Kuhla

Research Institute for Farm Animal Biology (FBN)
Head of working group Nutritional Biochemistry
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Research interests

  • Neuronal and metabolic control of feed intake
  • Links between feed efficiency, diet and methane production
  • Metabolic adaptation to environmental heat

Curriculum Vitae

  • 2013-present: Director of 'Fuel Sensing Unit', Leibniz Institute for Farm Animal Biology (FBN) Dummerstorf, Institute of Nutritional Physiology "Oskar Kellner"
  • 2009-2012: Leader of Junior Research Group „Feed Intake Regulation“, Leibniz Institute for Farm Animal Biology (FBN) Dummerstorf
  • 2006-present: Scientist at the Institute of Nutritional Physiology “Oskar Kellner”, Leibniz Institute for Farm Animal Biology (FBN) Dummerstorf
  • Habilitation and venia legendi in Biochemistry
  • Post Doc at the Agricultural Research Centre of the Bayer AG Monheim, University of Leipzig, and Case Western Reserve University, Cleveland
  • Diploma and Doctoral Degree in Chemistry
  • Secondary education and apprenticeship for animal production

Teaching

  • Anatomic-Physiological Basics and Methods in Animal Nutrition
  • Metabolism and performance physiology
  • Practical Course “Isolation of RNA from plant leaves”

Publications

Kuhla, B.; Görs, S.; Metges, C. C. (2011):
Hypothalamic orexin A expression and the involvement of AMPK and PPAR-gama signalling in energy restricted dairy cows. Arch Tierzucht 54 (6): 567-579
Niemann, H.; Kuhla, B.; Flachowsky, G. (2011):
Perspectives for feed-efficient animal production. J Anim Sci 89 (12): 4344-4363
https://dx.doi.org/10.2527/jas.2011-4235
Kuhla, B.; Nürnberg, G.; Albrecht, D.; Görs, S.; Hammon, H. M.; Metges, C. C. (2011):
Involvement of skeletal muscle protein, glycogen and fat metabolism in the adaptation on early lactation of dairy cows. J Proteome Res 10 (9): 4252-4262
https://dx.doi.org/10.1021/Pr200425h
Laeger, T.; Kuhla, B. (2011):
Feed restriction in dairy cows affects resistin levels in plasma and cerebrospinal fluid. Proc. Soc. Nutr. Physiol. 20: 141
Kuhla, B.; Görs, S.; Metges, C. C. (2011):
Changes of muscle amino acids, glycogen, and fat concentrations of dairy cows during the periparturient period . Proc. Soc. Nutr. Physiol. 20: 38
Kuhla, B.; Albrecht, D.; Bruckmaier, R. M.; Viergutz, T.; Nürnberg, G.; Metges, C. C. (2010):
Proteome and radioimmunoassay analyses of pituitary hormones and proteins in response to feed restriction of dairy cows. PROTEOMICS 10 (24): 4491-4500
https://dx.doi.org/10.1002/pmic.201000383
Kuhla, B.; Bellmann, O.; Metges, C. C. (2010):
Technical note: An apparatus for catheterization of the lateral brain ventricle in Holstein cows. J Dairy Sci 93 (12): 5837-5841
https://dx.doi.org/10.3168/jds.2010-3431
Derno, M.; Schwarm, A.; Kuhla, B.; Schweigel, M. (2010):
Phenotypic variation of energy intake and heat production in lactating cows fed ad libitum and restricted. In: Energy and protein metabolism and nutrition (G. Matteo Crovetto, Hrsg.) Wageningen Academic Publishers, Wageningen (978-90-8686-153-8): 319-320
Kuhla, B.; Kucia, M.; Görs, S.; Albrecht, D.; Langhammer, M.; Kuhla, B.; Metges, C. C. (2010):
Effect of a high-protein diet on food intake and liver metabolism during pregnancy, lactation and after weaning in mice. PROTEOMICS 10 (14): 2573-2588
https://dx.doi.org/10.1002/pmic.200900789
Laeger, T.; Metges, C. C.; Kuhla, B. (2010):
Role of β-hydroxybutyric acid in the central regulation of energy balance. Appetite 54 (3): 450-455
https://dx.doi.org/10.1016/j.appet.2010.04.005
Kuhla, B.; Albrecht, D.; Kuhla, B.; Metges, C. C. (2009):
Proteome analysis of fatty liver in feed-deprived dairy cows reveals interaction of fuel sensing, calcium, fatty acid, and glycogen metabolism. Physiol Genomics 37 (2): 88-98
https://dx.doi.org/10.1152/physiolgenomics.90381.2008
Hammon, H. M.; Kuhla, B.; Schweigel, M. (2009):
Energiedefizit moderner Milchkühe im Visier. Leibniz Nordost 2009 (8): 10-11
Schmidt, A.; Kuhla, B.; Bigl, K.; Münch, G.; Arendt, Th. (2007):
Cell cycle related signaling in neuro2a cells proceeds via the receptor for advanced glycation end products. J Neural Transm 114 (11): 1413-1424
https://dx.doi.org/10.1007/s00702-007-0770-0
Kuhla, B.; Kuhla, B.; Rudolph, P.E.; Albrecht, D.; Metges, C. C. (2007):
Proteomics analysis of hypothalamic response to energy restriction in dairy cows. PROTEOMICS 7 (19): 3602-3617
https://dx.doi.org/10.1002/pmic.200700248
Kuhla, B.; Haase, C; Flach, K; Lüth, HJ; Arendt, Th.; Münch, G. (2007):
Effect of Pseudophosphorylation and Cross-linking by Lipid Peroxidation and Advanced Glycation End Product Precursors on Tau Aggregation and Filament Formation. J Biol Chem 282 (10): 6984-6991
https://dx.doi.org/10.1074/jbc.M609521200
Kuhla, B.; Boeck, Katharina; Schmidt, Angela; Ogunlade, Vera; Arendt, Th.; Münch, G.; Lüth, HJ (2007):
Age- and stage-dependent glyoxalase I expression and its activity in normal and Alzheimer's disease brains. Neurobiol Aging 28 (1): 29-41
https://dx.doi.org/10.1016/j.neurobiolaging.2005.11.007
Kuhla, B.; Boeck, Katharina; Lüth, HJ; Schmidt, Angela; Weigle, Bernd; Schmitz, Marc; Ogunlade, Vera; Münch, G.; Arendt, Th. (2006):
Age-dependent changes of glyoxalase I expression in human brain. Neurobiol Aging 27 (6): 815-822
https://dx.doi.org/10.1016/j.neurobiolaging.2005.04.006
Kuhla, B.; Lüth, HJ; Haferburg, Dietrich; Weick, Michael; Reichenbach, Andreas; Arendt, Th.; Münch, G. (2006):
Pathological effects of glyoxalase I inhibition in SH-SY5Y neuroblastoma cells. J Neurosci Res 83 (8): 1591-1600
https://dx.doi.org/10.1002/jnr.20838