PD Dr. rer. nat. habil. Björn Kuhla

+49 38208 68-693
Research Institute for Farm Animal Biology (FBN)
Institute of Nutritional Physiology "Oskar Kellner"
Metabolism Efficiency Unit
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Research interests

  • Neuronal and metabolic control of feed intake
  • Links between feed efficiency, diet and methane production
  • Metabolic adaptation to environmental heat

Curriculum Vitae

  • 2013-present: Director of 'Fuel Sensing Unit', Leibniz Institute for Farm Animal Biology (FBN) Dummerstorf, Institute of Nutritional Physiology "Oskar Kellner"
  • 2009-2012: Leader of Junior Research Group „Feed Intake Regulation“, Leibniz Institute for Farm Animal Biology (FBN) Dummerstorf
  • 2006-present: Scientist at the Institute of Nutritional Physiology “Oskar Kellner”, Leibniz Institute for Farm Animal Biology (FBN) Dummerstorf
  • Habilitation and venia legendi in Biochemistry
  • Post Doc at the Agricultural Research Centre of the Bayer AG Monheim, University of Leipzig, and Case Western Reserve University, Cleveland
  • Diploma and Doctoral Degree in Chemistry
  • Secondary education and apprenticeship for animal production


  • Anatomic-Physiological Basics and Methods in Animal Nutrition
  • Metabolism and performance physiology
  • Practical Course “Isolation of RNA from plant leaves”


Laeger, T.; Hammon, H. M.; Kuhla, B. (2012):
Beta-hydroxybutyric acid/glucose ratio dependent orexigenic signaling in hypothalamic GT1-7 cells. Proc. Soc. Nutr. Physiol. 21: 52-52
Laeger, T.; Pöhland, R.; Metges, C. C.; Kuhla, B. (2012):
The ketone body β-hydroxybutyric acid influences agouti-related peptide expression via AMP-activated protein kinase in hypothalamic GT1-7 cells. J Endocrinol 213 (2): 193-203
Schäff, C. T.; Boener, S.; Hacke, S.; Kautsch, U.; Albrecht, D.; Hammon, H. M.; Röntgen, M.; Kuhla, B. (2012):
Increased Anaplerosis, TCA Cycling, and Oxidative Phosphorylation in the Liver of Dairy Cows with Intensive Body Fat Mobilization during Early Lactation. J Proteome Res 11 (11): 5503-5514
Schäff, C. T.; Albrecht, D.; Hammon, H. M.; Röntgen, M.; Metges, C. C.; Kuhla, B. (2012):
A longitudinal proteomic approach to investigate liver metabolism in periparturient dairy cows with different body fat mobilization. In: Farm Animal Proteomics : proceedings of the 3rd Managing Commitee Meeting and 2nd Meeting of the Working Groups 1,2 & 3 of COST Action FA1002 (Pedro Rodrigues, David Eckersall, Andre de Almeida, Hrsg.) Wageningen Academic Publishers, Wageningen (978-90-8686-195-8, 978-90-8686-751-6 eBook): 145-147
Kuhla, B. (2012):
Die Rolle von Carbonylen bei glycierungsabhängigen neurodegenerativen Prozessen und bei der neuronalen Kontrolle der Nahrungsaufnahme. Habilitationsschrift, Universität Rostock: 1-216
Kuhla, B.; Görs, S.; Metges, C. C. (2011):
Changes of muscle amino acids, glycogen, and fat concentrations of dairy cows during the periparturient period . Proc. Soc. Nutr. Physiol. 20: 38
Laeger, T.; Kuhla, B. (2011):
Feed restriction in dairy cows affects resistin levels in plasma and cerebrospinal fluid. Proc. Soc. Nutr. Physiol. 20: 141
Kuhla, B.; Nürnberg, G.; Albrecht, D.; Görs, S.; Hammon, H. M.; Metges, C. C. (2011):
Involvement of skeletal muscle protein, glycogen and fat metabolism in the adaptation on early lactation of dairy cows. J Proteome Res 10 (9): 4252-4262
Niemann, H.; Kuhla, B.; Flachowsky, G. (2011):
Perspectives for feed-efficient animal production. J Anim Sci 89 (12): 4344-4363
Kuhla, B.; Görs, S.; Metges, C. C. (2011):
Hypothalamic orexin A expression and the involvement of AMPK and PPAR-gama signalling in energy restricted dairy cows. Arch Tierzucht 54 (6): 567-579
Metges, C. C.; Hammon, H. M.; Kuhla, B.; Röntgen, M.; Souffrant, W.-B. (2011):
International Oskar Kellner Symposium: Metabolic Flexibility in Animal and Human Nutrition, Warnemünde 9.-11.9.2011, Programme with Abstracts (Schriftenreihe / Leibniz-Institut für Nutztierbiologie, 19) : 1-143
Laeger, T.; Metges, C. C.; Kuhla, B. (2010):
Role of β-hydroxybutyric acid in the central regulation of energy balance. Appetite 54 (3): 450-455
Kuhla, B.; Kucia, M.; Görs, S.; Albrecht, D.; Langhammer, M.; Kuhla, B.; Metges, C. C. (2010):
Effect of a high-protein diet on food intake and liver metabolism during pregnancy, lactation and after weaning in mice. PROTEOMICS 10 (14): 2573-2588
Derno, M.; Schwarm, A.; Kuhla, B.; Schweigel, M. (2010):
Phenotypic variation of energy intake and heat production in lactating cows fed ad libitum and restricted. In: Energy and protein metabolism and nutrition (G. Matteo Crovetto, Hrsg.) Wageningen Academic Publishers, Wageningen (978-90-8686-153-8): 319-320
Kuhla, B.; Bellmann, O.; Metges, C. C. (2010):
Technical note: An apparatus for catheterization of the lateral brain ventricle in Holstein cows. J Dairy Sci 93 (12): 5837-5841
Kuhla, B.; Albrecht, D.; Bruckmaier, R. M.; Viergutz, T.; Nürnberg, G.; Metges, C. C. (2010):
Proteome and radioimmunoassay analyses of pituitary hormones and proteins in response to feed restriction of dairy cows. PROTEOMICS 10 (24): 4491-4500
Hammon, H. M.; Kuhla, B.; Schweigel, M. (2009):
Energiedefizit moderner Milchkühe im Visier. Leibniz Nordost 2009 (8): 10-11
Kuhla, B.; Albrecht, D.; Kuhla, B.; Metges, C. C. (2009):
Proteome analysis of fatty liver in feed-deprived dairy cows reveals interaction of fuel sensing, calcium, fatty acid, and glycogen metabolism. Physiol Genomics 37 (2): 88-98
Kuhla, B.; Boeck, Katharina; Schmidt, Angela; Ogunlade, Vera; Arendt, Th.; Münch, G.; Lüth, HJ (2007):
Age- and stage-dependent glyoxalase I expression and its activity in normal and Alzheimer's disease brains. Neurobiol Aging 28 (1): 29-41
Kuhla, B.; Haase, C; Flach, K; Lüth, HJ; Arendt, Th.; Münch, G. (2007):
Effect of Pseudophosphorylation and Cross-linking by Lipid Peroxidation and Advanced Glycation End Product Precursors on Tau Aggregation and Filament Formation. J Biol Chem 282 (10): 6984-6991