PD Dr. rer. nat. habil. Bianka Grunow

+49 38208 68-852
Research Institute for Farm Animal Biology (FBN)
Institute of Muscle Biology & Growth
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Research interests

Examination of skeletal muscles in fish

  • Examination of the key processes in skeletal muscle development from embryo to adult fish
  • Investigation of meat quality in economically important species
  • Establishment of in vitro test systems from various tissues of different fish species

Professional Activities

Myogenesis in evolution: We will analyse possible similarities and differences of myogenesis in evolutionary diverse fish lineages.

Third-party projects:

Fish flesh quality: Establishment of sensory, physico-chemical and chemical measurement techniques for the supervision and the comparison of fish fillet in local fish species.

Third-party projects:

Establishment of cell cultures from fish tissue e.g. for the investigation of the effects of climate change on cell physiology


Wanka, H.; Lutze, P.; Staar, D.; Albers, A.; Bäumgen, I.; Grunow, B.; Peters, F. (2020):
Non-secretory renin reduces oxidative stress and increases cardiomyoblast survival during glucose and oxygen deprivation. Sci Rep-UK 10: 2329, 1-14
Hook, S.; Musa, S.; Ripley, D. M.; Hibbit, J.; Grunow, B.; Moritz, T.; Shiels, H. (2019):
Twins! Microsatellite analysis of two embryos within one egg case in oviparous elasmobranchs. Plos One 14 (12): e0224397
Hook, S.; McMurray, C.; Ripley, D.; Allen, N.; Moritz, T.; Grunow, B.; Shiels, H. (2019):
Recognition software successfully aids the identification of individual small-spotted catsharks Scyliorhinus canicula during their first year of life. J Fish Biol 95 (6): 1465-1470
Wanka, H.; Lutze, P.; Staar, D.; Grunow, B.; Peters, B. S.; Peters, J. (2018):
An alternative renin isoform is cardioprotective by modulating mitochondrial metabolism. J. Cell. Mol. Med. 1-11
Hodgson, P.; Ireland, J.; Grunow, B. (2018):
Fish, the better model in human heart research? Zebrafish Heart aggregates as a 3D spontaneously cardiomyogenic in vitro model system. Prog Biophys Mol Bio 138: 132-141
Noguera, P. A.; Grunow, B.; Klinger, M.; Lester, K.; Collet, B.; Del-Pozo, J. (2017):
Atlantic salmon cardiac primary cultures: An in vitro model to study viral host pathogen interactions and pathogenesis. PLoS One 12: e0181058
Lutze, P.; Wanka, H.; Baumgen, I.; Staar, D.; Grunow, B.; Peters, J. (2017):
An Alternative Promoter in Intron1 of the Renin Gene is Regulated by Glucose Starvation via Serum Response Factor. Cell Physiol Biochem 42: 1447-1457
Grunow, B.; Kirchhoff, T.; Moritz, T. (2016):
Stem cell expression and development of trunk musculature of lesser-spotted dogfish (Scyliorhinus canicula) reveal differences between sharks and teleosts. Acta Zool 98: 214-220
Grunow, B.; Mohamet, L.; Shiels, H. A. (2015):
Generating an in vitro 3D cell culture model from zebrafish larvae for heart research. J. Exp. Biol. 218: 1116-1121
Grunow, B.; Kirchhoff, T.; Lange, T.; Moritz, T.; S., H. (2015):
Histochemistry on vibratome sections of fish tissue: a comparison of fixation and embedding methods. . Aquat Biol 23: 251-263
Gebert, M.; Lüllwitz, L.; Grunow, B. (2014):
Neue Rohstoffe aus dem Bioreaktor- Fischzellkulturen für die Produktion von Fischmehl und Omega-3-Fettsäuren. . Foodlab 1: 16-19
Mehnert, J. M.; Brandenburger, M.; Grunow, B. (2013):
Electrophysiological characterization of spontaneously contracting cell aggregates obtained from rainbow trout larvae with multielectrode arrays. Cell Physiol Biochem 32: 1374-1385
Grunow, B.; Böhmert, B.; Fechner, K. (2013):
Specificity of antibodies established from mammals in rainbow trout (Oncorhynchus mykiss). . J. Appl. Ichthyol. 29: 1129-1133
Grunow, B. (2012):
Herzmodell: Herstellung von spontan kontrahierenden Kardiomyozytenverbände und deren Anwendung in der Herzforschung. . Südwestdeutscher Verlag für Hochschulschriften AG Co. KG 1-144
Grunow, B.; Schmidt, M.; Klinger, M.; Kruse, C. (2012):
Development of an in vitro cultivated, spontaneously and long-term contracting 3D heart model as a robust test system. J Cell Sci Ther 3: 1000116
Grunow, B.; Wenzel, J.; Terlau, H.; Langner, S.; Gebert, M.; Kruse, C. (2011):
In vitro developed spontaneously contracting cardiomyocytes from rainbow trout as a model system for human heart research. Cell Physiol Biochem 27: 1-12
Grunow, B.; Noglick, S.; Kruse, C.; Gebert, M. (2011):
Isolation of Cells from Atlantic sturgeon (Acipenser oxyrinchus oxyrinchus) and Optimization of Culture Conditions. Aquat Biol 14: 67-75
Grunow, B.; Wenzel, J.; Gebert, M.; Kruse, C. (2010):
In vitro generated autonomously contracting cardiomyocytes from rainbow trout as a model system for human heart research. . J. Biotechnol. 150: 6-7
Grunow, B.; Ciba, P.; Rakers, S.; Klinger, M.; Anders, E.; Kruse, C. (2010):
In vitro expansion of autonomously contracting, cardiomyogenic structures from rainbow trout Oncorhynchus mykiss. J. Fish Biol. 76: 427-434
Rakers, S.; Grunow, B.; Gebert, M.; Kruse, C. (2009):
Fish Cells grown in vitro are able to build Organoid-like Bodies and can be used for 3D-Cell Cultures. . European Aquaculture Society Special Publication 507-508