Dr. rer. nat. habil. Beate Fuchs

Research Institute for Farm Animal Biology (FBN)
Haed of Service group Metabolomics & Lipidomics
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Research interests

  • Regulation of lipid metabolism
  • Lipidomics, Metabolomics
  • Mass spectrometry & Analytics (GC-MS/MS, MALDI-TOF MS, TLC, HR-ESI-MS/MS)

Curriculum Vitae

  • 2017-present Head of Core Facility - Metabolomics, Leibniz Institute for Farm Animal Biology (FBN) Dummerstorf
  • 2016 Habilitation (Dr. rer. nat. habil.) at the Medical Faculty, University Leipzig
  • 2016 Research stay at the University of Pittsburgh, USA
  • 2009-2017 Independent Research Group Leader, DFG-funded research-project: HOCl-induced lysophospholipid generation from diacyl- and alkenyl-acyl phospholipids
  • 2007-2009 Scientific Co-worker at the Institute of Medical Physics and Bio¬physics at the Medi¬cal Faculty of the University of Leipzig
  • 2006 Research stay at the Strathclyde University in Glasgow, UK
  • 2004 Research stay at the University of Louisville, Kentucky, USA
  • 2002-2006 Postgraduate studies in Toxicology, University of Leipzig
  • 2002-2006 Postdoctoral fellowship of the Interdisciplinary Centre of Clinical Research of the Medical Faculty in Leipzig ("NMR and MALDI-TOF MS studies of cartilage degradation in rheumatoid arthritis: structure elucidation and clinical monitoring")
  • 1998-2001 PhD student at the Institute of Polymer Research in Dresden
  • Thesis: 19F NMR studies of irradiation-modified fluoropolymers
  • 1996-1997 Stipendiary of the Carl Duisberg foundation and trainee at Bayer de México in Mexico
  • 1996 Diploma Thesis at the Chair of Analytical Chemistry at the Univer¬sity of Freiberg (Topic: 31C NMR studies of structural changes of microbial treated brown coal)

Publications

Brenmoehl, J.; Brosig, E.; Trakooljul, N.; Walz, C.; Ohde, D.; Noce, A.; Walz, M.; Langhammer, M.; Petkov, S.; Röntgen, M.; Maak, S.; Galuska, C. E.; Fuchs, B.; Kuhla, B.; Ponsuksili, S.; Wimmers, K.; Hoeflich, A. (2023):
Metabolic Pathway Modeling in Muscle of Male Marathon Mice (DUhTP) and Controls (DUC) - a Possible Role of Lactate Dehydrogenase in Metabolic Flexibility. Cells-Basel 12 (15): 1925, 1-21
https://doi.org/10.3390/cells12151925
Ponsuksili, S.; Murani, E.; Hadlich, F.; Iqbal, M. A.; Fuchs, B.; Galuska, C. E.; Perdomo-Sabogal, A.; Sarais, F.; Trakooljul, N.; Reyer, H.; Oster, M.; Wimmers, K. (2022):
Prenatal transcript levels and metabolomics analyses reveal metabolic changes associated with intrauterine growth restriction and sex. Open Biol 12 (9): 220151, 1-13
https://doi.org/10.1098/rsob.220151
Chmiel, E.; Galuska, C. E.; Koper, P.; Kowalczyk, B.; Urbanik-Sypniewska, T.; Palusínska-Szysz, M.; Fuchs, B. (2022):
Unusual Lipid Components of Legionella gormanii Membranes. METABOLITES 12 (5): 418, 1-20
https://doi.org/10.3390/metabo12050418
Beckmann, L.; Künstner, A.; Freschi, M. L.; Huber, K.; Stölting, I.; Ibrahim, S. M.; Misa, H.; Freitag, J.; Langan, E. A.; Matschl, U.; Galuska, C. E.; Fuchs, B.; Knobloch, J. K.; Busch, H.; Raasch, M.-L. (2021):
Telmisartan induces a specific gut microbiota signature which may mediate its antiobesity effect. PHARMACOL RES 170: 105724, 1-14
https://doi.org/10.1016/j.phrs.2021.105724
Schilf, P.; Künstner, A.; Olbrich, M.; Waschina, S.; Fuchs, B.; Galuska, C. E.; Braun, A.; Neuschütz, K.; Seutter, M.; Bieber, K.; Hellberg, L.; Sina, C.; Laskay, T.; Rupp, J.; Ludwig, R.; Zillikens, D.; Busch, H.; Sadik, C. D.; Misa, H.; Ibrahim, S. M. (2021):
A Mitochondrial Polymorphism Alters Immune Cell Metabolism and Protects Mice from Skin Inflammation. Int J Mol Sci 22 (3): 1006, 1-22
https://doi.org/10.3390/ijms22031006
Engel, M.; Schiller, J.; Galuska, C.E.; Fuchs, B. (2021):
Phospholipases and Reactive Oxygen Species Derived Lipid Biomarkers in Healthy and Diseased Humans and Animals – A Focus on Lysophosphatidylcholine. Front Physiol 12: 732319,1-8
https://doi.org/10.3389/fphys.2021.732319
Wołczańska, A.; Christie, W. W.; Fuchs, B.; Galuska, C. E.; Kowalczyk, B.; Palusińska-Szysz, M. (2021):
Fatty acid composition and lipid profiles as chemotaxonomic markers of phytopathogenic fungi Puccinia malvacearum and P. glechomatis. FUNGAL BIOL-UK 125 (11): 869-878
https://doi.org/10.1016/j.funbio.2021.05.008
Gille, B.; Galuska, C. E.; Fuchs, B.; Peleg, S. (2021):
Recent advances in studying age-associated lipids alterations and dietary interventions in mammals. Front Aging 2: 773795, 1-7
https://doi.org/10.3389/fragi.2021.773795
Palusińska-Szysz, M.; Szuster-Ciesielska, A.; Janczarek, M.; Wdowiak-Wróbel, S.; Schiller, J.; Reszczyńska, E.; Gruszecki, W.; Fuchs, B. (2019):
Genetic diversity of Legionella pcs and pmt genes and the effect of utilization of choline by Legionella spp. on induction of proinflammatory cytokines. Pathog Dis 77: ftz065, 1-13
https://doi.org/10.1093/femspd/ftz065
de Diego, I.; Peleg, S.; Fuchs, B. (2019):
The role of lipids in aging-related metabolic changes. Chem Phys Lipids 222: 59-69
https://doi.org/10.1016/j.chemphyslip.2019.05.005
Ditz, T.; Schnapka-Hille, L.; Noack, N.; Dorow, J.; Ceglarek, U.; Niederwieser, D.; Schiller, J.; Fuchs, B.; Cross, M. (2019):
Phospholipase A2 products predict the hematopoietic support capacity of horse serum. Differentiation 105: 27-32
https://doi.org/10.1016/j.diff.2018.12.002
Ditz, T.; Fuchs, B. (2018):
Determination of the phosphatidylcholine/lysophosphatidylcholine ratio in intact serum by matrix-assisted laser desorption/ionisation mass spectrometry with prior enzymatic albumin digestion. Lipids 53: 971-977
https://doi.org/10.1002/lipd.12106
Broniec, A.; Zadlo, A.; Pawlak, A.; Fuchs, B.; Klosinski, R.; Thompson, D.; Sarna, T. (2017):
Interaction of plasmenylcholine with free radicals in selected model systems. Free Radic Biol Med 106: 368-378
Schroter, J.; Griesinger, H.; Reuss, E.; Schulz, M.; Riemer, T.; Suss, R.; Schiller, J.; Fuchs, B. (2016):
Unexpected products of the hypochlorous acid-induced oxidation of oleic acid: A study using high performance thin-layer chromatography-electrospray ionization mass spectrometry. J. Chromatogr. 1439: 89-96
Dinkla, S.; van Eijk, L. T.; Fuchs, B.; Schiller, J.; Joosten, I.; Brock, R.; Pickkers, P.; Bosman, G. J. (2016):
Inflammation-associated changes in lipid composition and the organization of the erythrocyte membrane. BBA Clin 5: 186-192
Fuchs, B.; Popkova, Y.; Suss, R.; Schiller, J. (2015):
Separation of (Phospho)Lipids by Thin-Layer Chromatography. Instrumental Thin-Layer Chromatography 375-405
Fuchs, B. (2015):
Analytical methods for (oxidized) plasmalogens: Methodological aspects and applications. Free Radical Research 49: 599-617
Palusinska-Szysz, M.; Kania, M.; Turska-Szewczuk, A.; Danikiewicz, W.; Russa, R.; Fuchs, B. (2014):
Identification of Unusual Phospholipid Fatty Acyl Compositions of Acanthamoeba castellanii. Plos One 9: e01243
Griesinger, H.; Fuchs, B.; Suss, R.; Matheis, K.; Schulz, M.; Schiller, J. (2014):
Stationary phase thickness determines the quality of thin-layer chromatography/matrix-assisted laser desorption and ionization mass spectra of lipids. Anal. Biochem. 451: 45-47
Fuchs, B.; Schiller, J. (2014):
Glycosaminoglycan degradation by selected reactive oxygen species. Antioxid. Redox Signal. 21: 1044-1062