Dr. rer. nat. Alexander Rebl

+49 38208 68-702

rebl@fbn-dummerstorf.de

Research Institute for Farm Animal Biology (FBN)
Institute of Genome Biology
Fish Genetics Unit
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

ResearchGate

Research interests

Structural and functional characterization of signaling cascades in bony fish activated in response to a pathogenic stimulus: Our investigation mainly focuses on innate immune mechanisms comprising the Toll-like receptor signaling cascade, the complement system, acute-phase reactants, and cytokine networks in teleosts.

Curriculum Vitae

2014-present: Scientist, Member of the Fish Genetics Unit, Leibniz Institute for Farm Animal Biology (FBN)
2009-2014: Junior Group Leader, Fish Genetics Unit, Leibniz Institute for Farm Animal Biology (FBN),
2007-2009: Postdoctoral Fellow, Fish Genetics Unit, Leibniz Institute for Farm Animal Biology (FBN)
2007: Ph.D. in Molecular Biology
2004-2007: PhD Student, University of Rostock
1999-2004: Diploma, University of Rostock

Publications

Brietzke, A.; Goldammer, T.; Rebl, H.; Korytar, T.; Köllner, B.; Yang, W.; Rebl, A.; Seyfert, H.-M. (2014):

Characterization of the interleukin 1 receptor-associated kinase 4 (IRAK4)-encoding gene in salmonid fish: the functional copy is rearranged in Oncorhynchus mykiss and that factor can impair TLR signaling in mammalian cells. Fish Shellfish Immun 36 (1): 206-214

Tom Goldammer, Alexander Rebl

https://dx.doi.org/10.1016/j.fsi.2013.11.005

Rebl, A.; Korytar, T.; Köbis, J.; Verleih, M.; Krasnov, A.; Jaros, J.; Kühn, C.; Köllner, B.; Goldammer, T. (2014):

Transcriptome profiling reveals insight into distinct immune responses to Aeromonas salmonicida in gill of two rainbow trout strains. Mar Biotechnol 16 (4): 333-348

Alexander Rebl, Marieke Verleih, Tom Goldammer

https://dx.doi.org/10.1007/s10126-013-9552-x

Goldammer, T.; Rebl, A.; Verleih, M.; Köllner, B.; Korytar, T.; Kühn, C. (2013):

Standortgerechte Fischproduktion: Robuste Forellen für die ökologische Teichwirtschaft gezüchtet. Forschungsreport (Spezial 2): 10-11

Tom Goldammer, Alexander Rebl, Marieke Verleih

Rebl, A.; Verleih, M.; Köbis, J.; Kühn, C.; Wimmers, K.; Köllner, B.; Goldammer, T. (2013):

Transcriptome profiling of gill tissue in regionally bred and globally farmed rainbow trout strains reveals different strategies for coping with thermal stress. Mar Biotechnol 15 (4): 445-460

Alexander Rebl, Marieke Verleih, Klaus Wimmers, Tom Goldammer

https://dx.doi.org/10.1007/s10126-013-9501-8

Köbis, J.; Rebl, A.; Kühn, C.; Goldammer, T. (2013):

Comparison of splenic transcriptome activity of two rainbow trout strains differing in robustness under regional aquaculture conditions. Mol Biol Rep 40 (2): 1955-1966

Alexander Rebl, Tom Goldammer

https://dx.doi.org/10.1007/s11033-012-2252-1

Korytar, T.; Jaros, J.; Verleih, M.; Rebl, A.; Kotterba, G.; Kühn, C.; Goldammer, T.; Köllner, B. (2013):

Novel insights into the peritoneal inflammation of rainbow trout (Oncorhynchus mykiss). Fish Shellfish Immun 35 (4): 1192-1199

Marieke Verleih, Alexander Rebl, Tom Goldammer

https://dx.doi.org/10.1016/j.fsi.2013.07.032

Verleih, M.; Rebl, A.; Köllner, B.; Korytar, T.; Köbis, J.; Kühn, C.; Wimmers, K.; Goldammer, T. (2013):

Iron-sulfur cluster scaffold (ISCU) gene is duplicated in salmonid fish and tissue and temperature dependent expressed in rainbow trout. Gene 512 (2): 251-258

Marieke Verleih, Alexander Rebl, Klaus Wimmers, Tom Goldammer

https://dx.doi.org/10.1016/j.gene.2012.10.037

Köbis, J.; Rebl, A.; Goldammer, T. (2012):

13th Day of the Doctoral Student, Dummerstorf, BRD. In: Different expression patterns of innate immune genes in two rainbow trout strains (Editoren:H.-M. Seyfert, G. Viereck, Hrsg.) Leibniz-Institut für Nutztierbiologie (FBN), Dummerstorf (0946-1981) (20): 47-50

Alexander Rebl, Tom Goldammer

Perucatti, A.; Genualdo, V.; Iannuzzi, A.; Rebl, A.; Di Berardino, D.; Goldammer, T.; Iannuzzi, L. (2012):

Advanced comparative cytogenetic analysis of X chromosomes in river buffalo, cattle, sheep, and human. Chromosome Res 20 (4): 413-425

Alexander Rebl, Tom Goldammer

https://dx.doi.org/10.1007/s10577-012-9285-0

Rebl, A.; Verleih, M.; Köllner, B.; Korytar, T.; Goldammer, T. (2012):

Duplicated NELL2 genes show different expression patterns in two rainbow trout strains after temperature and pathogen challenge. Comp Biochem Phys B 163 (1): 65-73

Alexander Rebl, Marieke Verleih, Tom Goldammer

https://dx.doi.org/10.1016/j.cbpb.2012.05.001

Verleih, M.; Rebl, A.; Köllner, B.; Korytar, T.; Anders, E.; Wimmers, K.; Goldammer, T. (2012):

Comparative molecular characterization of the regucalcin (RGN) gene in rainbow trout (Oncorhynchus mykiss) and maraena whitefish (Coregonus marena). Mol Biol Rep 39 (4): 4291-4300

Marieke Verleih, Alexander Rebl, Klaus Wimmers, Tom Goldammer

https://dx.doi.org/10.1007/s11033-011-1216-1

Rebl, A.; Verleih, M.; Korytar, T.; Kühn, C.; Wimmers, K.; Köllner, B.; Goldammer, T. (2012):

Identification of differentially expressed protective genes in liver of two rainbow trout strains. VET IMMUNOL IMMUNOP 145 (1-2): 305-315

Alexander Rebl, Marieke Verleih, Klaus Wimmers, Tom Goldammer

https://dx.doi.org/10.1016/j.vetimm.2011.11.023

Yerebakan, C.; Niefeldt, S.; Klopsch, C.; Prietz, S.; Rebl, A.; Goldammer, T.; Boltze, J.; Sandica, E.; Steinhoff, G. (2011):

Regenerative Therapien für Kinderherzen. Zeitschrift für Herz-, Thorax- und Gefäßchirurgie 25 (4): 235-240

Alexander Rebl, Tom Goldammer

https://dx.doi.org/10.1007/s00398-011-0862-x

Verleih, M.; Rebl, A.; Köllner, B.; Korytar, T.; Kühn, C.; Wimmers, K.; Goldammer, T. (2011):

Comparative analyses of apoptosis-related candidate genes in rainbow trout: molecular characterization and transcriptome analyses. In: Comparative analyses of apoptosis-related candidate genes in rainbow trout: molecular characterization and transcriptome analyses (Schwerin M. Editoren Heft 18: Seyfert, H-M, Viereck G, Hrsg.) BUK!, Kiel (0946-1981) (18): 39-41

Marieke Verleih, Alexander Rebl, Klaus Wimmers, Tom Goldammer

Di Meo, G. P.; Goldammer, T.; Perucatti, A.; Genualdo, V.; Iannuzzi, A.; Incarnato, D.; Rebl, A.; Di Berardino, D.; Iannuzzi, L. (2011):

Extended cytogenetic maps of sheep chromosome 1 and their cattle and river buffalo homoeologues: comparison with the OAR1 RH map and human chromosomes 2, 3, 21 and 1q. Cytogenet Genome Res 133 (1): 16-24

Tom Goldammer, Alexander Rebl

https://dx.doi.org/10.1159/000323796

Rebl, A.; Köbis, J.; Fischer, K.; Takizawa, F.; Verleih, M.; Wimmers, K.; Goldammer, T. (2011):

MARCH5 gene is duplicated in rainbow trout, but only fish-specific gene copy is up-regulated after VHSV infection.. Fish Shellfish Immun 31 (6): 1041-1050

Alexander Rebl, Marieke Verleih, Klaus Wimmers, Tom Goldammer

https://dx.doi.org/10.1016/j.fsi.2011.09.004

Rebl, A.; Rebl, H.; Liu, S.; Goldammer, T.; Seyfert, H.-M. (2011):

Salmonid Tollip and MyD88 factors can functionally replace their mammalian orthologues in TLR-mediated trout SAA promoter activation. Dev Comp Immunol 35 (1): 81-87

Alexander Rebl, Tom Goldammer

https://dx.doi.org/10.1016/j.dci.2010.08.012

Verleih, M.; Rebl, A.; Köllner, B.; Korytar, T.; Kotterba, G.; Anders, E.; Wimmers, K.; Goldammer, T. (2010):

Molecular characterization of PRR13 and its tissue-specific expression in rainbow trout (Oncorhynchus mykiss). Fish Physiol Biochem 36 (4): 1271-1276

Marieke Verleih, Alexander Rebl, Klaus Wimmers, Tom Goldammer

https://dx.doi.org/10.1007/s10695-010-9407-6

Rebl, A.; Goldammer, T.; Seyfert, H.-M. (2010):

Toll-like receptor signaling in bony fish. VET IMMUNOL IMMUNOP 134 (3-4): 139-150

Alexander Rebl, Tom Goldammer

https://dx.doi.org/10.1016/j.vetimm.2009.09.021

Rebl, A.; Anders, E.; Wimmers, K.; Goldammer, T. (2009):

Cloning and tissue-specific expression of a delta-COP homologue in a freshwater and a brackish water-adapted strain of rainbow trout (Oncorhynchus mykiss). Genes Genet Syst 84 (3): 239-243

Alexander Rebl, Klaus Wimmers, Tom Goldammer

https://dx.doi.org/10.1266/ggs.84.239