Dr. rer. nat. Alexander Rebl
Research interests
- Understanding immunological and stress-induced physiological mechanisms for the optimisation of health concepts in aquaculture
- Recording the genomic differences between individuals and populations of established and new aquaculture fish species with regard to immunocompetence and performance
Curriculum Vitae
- 2014-today: Scientist in the working group Fish Genetics at the Research Institute for Farm Animal Biology (FBN) Dummerstorf
- 2009-2014: Leader of the junior research group Genetics of Immune Defence in Fish at the FBN
- 2007-2009: Postdoc in the Fish Genetics Unit at the FBN
- 2004-2007: PhD in Molecular Biology at the University of Rostock
- 1999-2004: Diploma in Biology at the University of Rostock
Publications
Zlatina, K.; Saftenberger, M.; Kühnle, A.; Galuska, C.E.; Gärtner, U.; Rebl, A.; Oster, M.; Vernunft, A.; Galuska, S. P. (2018):
Polysialic acid in human plasma can compensate the cytotoxicity of histones. Int J Mol Sci 19 (6): 1679, 1-10
https://doi.org/10.3390/ijms18061679
Bornhöfft, K.; Goldammer, T.; Rebl, A.; Galuska, S. P. (2018):
Siglecs: a journey through the evolution of sialic acid-binding immunoglobulin-type lectins. Dev Comp Immunol 86: 219-231
https://doi.org/10.1016/j.dci.2018.05.008
Borchel, A.; Komisarczuk, A.; Rebl, A.; Goldammer, T.; Nilsen, F. (2018):
Systematic identification and characterization of stress-inducible heat shock proteins (HSPs) in the salmon louse (Lepeophtheirus salmonis). CELL STRESS CHAPERON 23 (1): 127-139
https://doi.org/10.1007/s12192-017-0830-9
Wirthgen, E.; Hoeflich, A.; Rebl, A.; Günther, J. (2017):
Kynurenic acid: The Janus-faced role of an immunomodulatory tryptophan metabolite and its link to pathological conditions. Front Immunol 8: 1957, 1-13
https://dx.doi.org/10.3389/fimmu.2017.01957
Galow, A.M.; Rebl, A.; Koczan, D.; Bonk, S. M.; Baumann, W.; Gimsa, J. (2017):
Increased osteoblast viability at alkaline pH in vitro provides a new perspective on bone regeneration. Biochem Biophys Rep 10: 17-25
https://dx.doi.org/10.1016/j.bbrep.2017.02.001
Rebl, A.; Zebunke, M.; Borchel, A.; Bochert, R.; Verleih, M.; Goldammer, T. (2017):
Microarray-predicted marker genes and molecular pathways indicating crowding stress in rainbow trout (Oncorhynchus mykiss). Aquaculture 473: 355-365
doi.org/10.1016/j.aquaculture.2017.03.003
Borchel, A.; Verleih, M.; Rebl, A.; Goldammer, T. (2017):
Identification of genes involved in cold-shock response in rainbow trout (Oncorhynchus mykiss). J Genet 96 (4): 701-706
https://dx.doi.org/10.1007/s12041-017-0811-X
Galow, A.-M.; Rebl, A.; Koczan, D.; Gimsa, J. (2017):
MC3T3 osteoblast-like cells cultured at alkaline pH: microarray data (Affymetrix GeneChip Mouse 2.0 ST). Data in brief 13: 108-114
https://dx.doi.org/10.1016/j.dib.2017.05.013
Köbis, J.; Rebl, H.; Goldammer, T.; Rebl, A. (2017):
Multiple gene and transcript variants encoding trout C-polysaccharide binding proteins are differentially but strongly induced after infection with Aeromonas salmonicida. Fish Shellfish Immun 60: 509-519
https://dx.doi.org/10.1016/j.fsi.2016.11.021
Rebl, A.; Rebl, H.; Köbis, J.; Goldammer, T.; Seyfert, H.-M. (2017):
ST2 from rainbow trout quenches TLR signalling, localises at the nuclear membrane and allows the nuclear translocation of MYD88. Dev Comp Immunol 67: 139-152
https://dx.doi.org/10.1016/j.dci.2016.10.009
Korytar, T.; Nipkow, M.; Altmann, S.; Goldammer, T.; Köllner, B.; Rebl, A. (2016):
Adverse husbandry of Maraena whitefish directs the immune system to increase mobilization of myeloid cells and proinflammatory responses. Front Immunol 7: 631, 1-14
https://dx.doi.org/10.3389/fimmu.2016.00631
Goldammer, T.; Rebl, A.; Köllner, B.; Kühn, C. (2016):
Genetische Biomarker zur Evaluierung einer standortgerechten Aquakultur in M-V – Ergebnisse der EFF-Pilotprojekte Regenbogenforelle Stamm BORN und Ostseeschnäpel. Fischerei und Fischmarkt in Mecklenburg-Vorpommern 16 (3): 32-41
Altmann, S.; Korytar, T.; Kaczmarzyk, D.; Nipkow, M.; Kühn, C.; Goldammer, T.; Rebl, A. (2016):
Toll-like receptors in maraena whitefish: Evolutionary relationship among salmonid fishes and patterns of response to Aeromonas salmonicida. Fish Shellfish Immun 54: 391-401
https://dx.doi.org/10.1016/j.fsi.2016.04.125
Brietzke, A.; Arnemo, M.; Gjøen, T.; Rebl, H.; Korytar, T.; Goldammer, T.; Rebl, A.; Seyfert, H.-M. (2016):
Structurally diverse genes encode TLR2 in rainbow trout: The conserved receptor cannot be stimulated by classical ligands to activate NF-kB in vitro. Dev Comp Immunol 54 (1): 75-88
https://dx.doi.org/10.1016/j.dci.2015.08.012
Altmann, S.; Rebl, A.; Kühn, C.; Goldammer, T. (2015):
Identification and de novo sequencing of housekeeping genes appropriate for gene expression analyses in farmed maraena whitefish (Coregonus maraena) during crowding stress. Fish Physiol Biochem 41 (2): 397-412
https://dx.doi.org/10.1007/s10695-014-9991-y
Verleih, M.; Borchel, A.; Krasnov, A.; Rebl, A.; Korytar, T.; Kühn, C.; Goldammer, T. (2015):
Impact of thermal stress on kidney-specific gene expression in farmed regional and imported rainbow trout. Mar Biotechnol 17 (5): 576-592
https://dx.doi.org/10.1007/s10126-015-9640-1
Rebl, A.; Nipkow, M.; Goldammer, T.; Kühn, C. (2015):
Ostseeschnäpel aus regionaler Aquakultur : Wie kann Haltungsstress aufgedeckt werden?. Forschungsreport 51: 4-7
Brietzke, J.; Korytar, T.; Jaros, J.; Köllner, B.; Goldammer, T.; Seyfert, H.-M.; Rebl, A. (2015):
Aeromonas salmonicida infection only moderately regulates expression of factors contributing to toll-like receptor signaling but massively activates the cellular and humoral branches of innate immunity in rainbow trout (Oncorhynchus mykiss). J Immunol Res 2015: 901015, 1-16
https://dx.doi.org/10.1155/2015/901015