Dr. rer. nat. Alexander Rebl

+49 38208 68-702

rebl@fbn-dummerstorf.de

Research Institute for Farm Animal Biology (FBN)
Institute of Genome Biology
Fish Genetics Unit
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

ResearchGate

Research interests

Structural and functional characterization of signaling cascades in bony fish activated in response to a pathogenic stimulus: Our investigation mainly focuses on innate immune mechanisms comprising the Toll-like receptor signaling cascade, the complement system, acute-phase reactants, and cytokine networks in teleosts.

Curriculum Vitae

2014-present: Scientist, Member of the Fish Genetics Unit, Leibniz Institute for Farm Animal Biology (FBN)
2009-2014: Junior Group Leader, Fish Genetics Unit, Leibniz Institute for Farm Animal Biology (FBN),
2007-2009: Postdoctoral Fellow, Fish Genetics Unit, Leibniz Institute for Farm Animal Biology (FBN)
2007: Ph.D. in Molecular Biology
2004-2007: PhD Student, University of Rostock
1999-2004: Diploma, University of Rostock

Publications

Venuto, M. T.; Decloquement, M.; Martorell Ribera, J.; Noel, M.; Rebl, A.; Cogez, V.; Petit, D.; Galuska, S. P.; Harduin-Lepers, A. (2020):

Vertebrate Alpha2,8-Sialyltransferases (ST8Sia): A Teleost Perspective. Int J Mol Sci 21 (2): 513, 1-21

Alexander Rebl, Sebastian Peter Galuska

https://doi.org/10.3390/ijms21020513

Koll, R.; Martorell Ribera, J.; Brunner, R. M.; Rebl, A.; Goldammer, T. (2020):

Gene profiling in the adipose fin of salmonid fishes supports its function as a flow sensor. Genes-Basel 11 (1): 21, 1-22

Tom Goldammer, Alexander Rebl, Ronald Brunner

https://doi.org/10.3390/genes11010021

Martorell Ribera, J.; Nipkow, M.; Viergutz, T.; Brunner, R. M.; Bochert, R.; Koll, R.; Goldammer, T.; Gimsa, U.; Rebl, A. (2020):

Early response of salmonid head-kidney cells to stress hormones and toll-like receptor ligands. Fish Shellfish Immun 98: 950-961

Ronald Brunner, Tom Goldammer, Ulrike Gimsa, Alexander Rebl

https://doi.org/10.1016/j.fsi.2019.11.058

Nguinkal, J. A.; Brunner, R. M.; Verleih, M.; Rebl, A.; de los Rios Pérez, L.; Schäfer, N.; Hadlich, F.; Stüeken, M.; Wittenburg, D.; Goldammer, T. (2019):

The first highly contiguous genome assembly of pikeperch (Sander lucioperca), an emerging aquaculture species in Europe. Genes-Basel 10: 708, 1-14

Ronald Brunner, Marieke Verleih, Alexander Rebl, Tom Goldammer, Dörte Wittenburg

https://doi.org/10.3390/genes10090708

Borchel, A.; Verleih, M.; Kühn, C.; Rebl, A.; Goldammer, T. (2019):

Evolutionary expression differences of creatine synthesis-related genes: Implications for skeletal muscle metabolism in fish. Sci Rep-UK 9: 5429, 1-8

Marieke Verleih, Alexander Rebl, Tom Goldammer

https://doi.org/10.1038/s41598-019-41907-6

Verleih, M.; Borchel, A.; Rebl, A.; Brenmoehl, J.; Kühn, C.; Goldammer, T. (2019):

A molecular survey of programmed cell death in rainbow trout: Structural and functional specifications of apoptotic key molecules. Comp Biochem Phys B 230: 57-69

Marieke Verleih, Alexander Rebl, Julia Brenmoehl, Tom Goldammer

https://doi.org/10.1016/j.cbpb.2019.01.012

Montero, R.; Strzelczyk, J.; Tze Ho Chan, J.; Verleih, M.; Rebl, A.; Goldammer, T.; Köllner, B.; Korytár, T. (2019):

Dawn to dusk: Diurnal rhythm of the immune response in rainbow trout (Oncorhynchus mykiss). BIOLOGY-BASEL 9 (1): 8, 1-13

Marieke Verleih, Alexander Rebl, Tom Goldammer

https://doi.org/10.3390/biology9010008

Rebl, A.; Rebl, H.; Verleih, M.; Haupt, S.; Goldammer, T.; Seyfert, H.-M. (2019):

At least two genes encode many variants of Irak3 in rainbow trout, but neither the full-length factor nor its variants interfere directly with the TLR-mediated stimulation of inflammation. Front Immunol 10: 2246, 1-19

Alexander Rebl, Marieke Verleih, Tom Goldammer

https://doi.org/10.3389/fimmu.2019.02246. eCollection 2019.

Bornhöfft, K.; Rebl, A.; Gallagher, M.E.; Viergutz, T.; Zlatina, K.; Reid, C.; Galuska, S. P. (2019):

Sialylated cervical mucins inhibit the activation of neutrophils to form neutrophil extracellular traps in bovine in vitro model. Front Immunol 10: 2478, 1-15

Alexander Rebl, Kristina Zlatina, Sebastian Peter Galuska

https://doi.org/10.3389/fimmu.2019.02478

Swirplies, F.; Würtz, S.; Baßmann, B.; Orban, A.; Schäfer, N.; Brunner, R. M.; Hadlich, F.; Goldammer, T.; Rebl, A. (2019):

Identification of molecular stress indicators in pikeperch Sander lucioperca correlating with rising water temperatures. Aquaculture 501: 260-271

Tom Goldammer, Ronald Brunner, Alexander Rebl

https://doi.org/10.1016/j.aquaculture.2018.11.043

Strubl, S.; Schubert, U; Kühnle, A.; Rebl, A.; Ahmadvand, N.; Fischer, S.; Preissner, K.; Galuska, S. P. (2018):

Polysialic acid is released by human umbilical vein endothelial cells (HUVEC) in vitro. Cell Biosci 8 (64):

Alexander Rebl, Sebastian Peter Galuska

https://doi.org/10.1186/s13578-018-0262-y

Rebl, A.; Verleih, M.; Nipkow, M.; Altmann, S.; Bochert, R.; Goldammer, T. (2018):

Gradual and acute temperature rise induces crossing endocrine, metabolic, and immunological pathways in Maraena whitefish (Coregonus maraena). Front Genet 9: 241, 1-16

Alexander Rebl, Marieke Verleih, Tom Goldammer

https://doi.org/10.3389/fgene.2018.00241

Nipkow, M.; Wirthgen, E.; Luft, P.; Rebl, A.; Hoeflich, A.; Goldammer, T. (2018):

Characterization of igf1 and igf2 genes during maraena whitefish (Coregonus maraena) ontogeny and the effect of temperature on embryogenesis and igf expression. Growth Horm IGF Res 40: 32-43

Alexander Rebl, Andreas Höflich, Tom Goldammer

https://doi.org/10.1016/j.ghir.2018.04.003

Rebl, A.; Goldammer, T. (2018):

Under control: the innate immunity of fish from the inhibitors' perspective. Fish Shellfish Immun 77: 328-349

Alexander Rebl, Tom Goldammer

https://doi.org/doi: 10.1016/j.fsi.2018.04.016

Zlatina, K.; Saftenberger, M.; Kühnle, A.; Galuska, C.E.; Gärtner, U.; Rebl, A.; Oster, M.; Vernunft, A.; Galuska, S. P. (2018):

Polysialic acid in human plasma can compensate the cytotoxicity of histones. Int J Mol Sci 19 (6): 1679, 1-10

Kristina Zlatina, Christina Galuska, Alexander Rebl, Michael Oster, Andreas Vernunft, Sebastian Peter Galuska

https://doi.org/10.3390/ijms18061679

Bornhöfft, K.; Goldammer, T.; Rebl, A.; Galuska, S. P. (2018):

Siglecs: a journey through the evolution of sialic acid-binding immunoglobulin-type lectins. Dev Comp Immunol 86: 219-231

Tom Goldammer, Alexander Rebl, Sebastian Peter Galuska

https://doi.org/10.1016/j.dci.2018.05.008

Borchel, A.; Komisarczuk, A.; Rebl, A.; Goldammer, T.; Nilsen, F. (2018):

Systematic identification and characterization of stress-inducible heat shock proteins (HSPs) in the salmon louse (Lepeophtheirus salmonis). CELL STRESS CHAPERON 23 (1): 127-139

Alexander Rebl, Tom Goldammer

https://doi.org/10.1007/s12192-017-0830-9

Wirthgen, E.; Hoeflich, A.; Rebl, A.; Günther, J. (2017):

Kynurenic acid: The Janus-faced role of an immunomodulatory tryptophan metabolite and its link to pathological conditions. Front Immunol 8: 1957, 1-13

Andreas Höflich, Alexander Rebl, Juliane Günther

https://dx.doi.org/10.3389/fimmu.2017.01957

Galow, A.M.; Rebl, A.; Koczan, D.; Bonk, S. M.; Baumann, W.; Gimsa, J. (2017):

Increased osteoblast viability at alkaline pH in vitro provides a new perspective on bone regeneration. Biochem Biophys Rep 10: 17-25

Alexander Rebl

https://dx.doi.org/10.1016/j.bbrep.2017.02.001

Rebl, A.; Zebunke, M.; Borchel, A.; Bochert, R.; Verleih, M.; Goldammer, T. (2017):

Microarray-predicted marker genes and molecular pathways indicating crowding stress in rainbow trout (Oncorhynchus mykiss). Aquaculture 473: 355-365

Alexander Rebl, Marieke Verleih, Tom Goldammer

doi.org/10.1016/j.aquaculture.2017.03.003