PD Dr. biol. hom. Sebastian Peter Galuska

+49 38208 68 752
Leibniz Institute for Farm Animal Biology (FBN)
Institute of Reproductive Biology
Junior research group Glycobiology
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Research interests

  • Glycobiology
  • Reproductive Biology
  • Immunology
  • Glycoanalytic

Curriculum Vitae

  • since 2016: Junior Group Leader at the Institute of Reproductive Biology, Leibniz Institute for Farm Animal Biology (FBN), Dummerstorf, Germany
  • 2012-2016: Junior Group leader at the Institute of Biochemistry, Medical Faculty of the Justus-Liebig University, Giessen, Germany
  • 2008-2012: Postdoctoral Research Fellow at the Institute of Biochemistry, Medical Faculty of the Justus-Liebig University, Giessen, Germany
  • 2008: Dr. in human biology, Dr. biol. hom.
  • 2003-2008: PhD student at the Institute of Biochemistry, Medical Faculty of the Justus-Liebig University, Giessen, Germany
  • 2003: Dipl. Ing. in Biotechnology
  • 1999-2003: Studies in Biotechnology at the University of applied Sciences Giessen/Friedberg (THM), Germany, Germany

Teaching

since 2005: Different practical courses, seminars and lectures in the disciplines of biology and biochemistry in the Medical Faculty as well as in the Faculty of Psychology and Sports Science at the Justus-Liebig University Giessen, Germany

Publications

Kronimus, Y.; Dodel, R.; Galuska, S. P.; Neumann, S. (2019):
IgG Fc N-glycosylation: Alterations in neurologic diseases and potential therapeutic target?. J Autoimmun 96: 14-23
Kühnle, A.; Veelken, R.; Galuska, C.E.; Saftenberger, M.; Verleih, M.; Schuppe, H.C.; Rudloff, S.; Kunz, C.; Galuska, S. P. (2019):
Polysialic acid interacts with lactoferrin and supports its activity to inhibit the release of neutrophil extracellular traps. Carbohyd Polym 208: 32-41
Zlatina, K.; Galuska, S. P. (2019):
Polysialic acid modulates only the antimicrobial properties of distinct histones. ACS Omega 4 (1): 1601-1610
Kühnle, A.; Lütteke, T.; Bornhöfft, K.; Galuska, S. P. (2019):
Polysialic acid modulates the binding of external lactoferrin in neutrophil extracellular traps. Biology 8 (2): 20
Bornhöfft, K.; Galuska, S. P. (2019):
Glycans as modulators for the formation and functional properties of neutrophil extracellular traps: used by the forces of good and evil. Front Immunol 10: 959, 1-9
Bornhöfft, K.; Gallagher, M.E.; Viergutz, T.; Zlatina, K.; Reid, C.; Galuska, S. P.; Rebl, A. (2019):
Sialylated cervical mucins inhibit the activation of neutrophils to form neutrophil extracellular traps in bovine in vitro model. Front Immunol (https://doi.org/10.3389/fimmu.2019.02478)
Bornhöfft, K.; Goldammer, T.; Rebl, A.; Galuska, S. P. (2018):
Siglecs: a journey through the evolution of sialic acid-binding immunoglobulin-type lectins. Dev Comp Immunol 86: 219-231
Zlatina, K.; Saftenberger, M.; Kühnle, A.; Galuska, C.E.; Gärtner, U.; Rebl, A.; Oster, M.; Vernunft, A.; Galuska, S. P. (2018):
Polysialic acid in human plasma can compensate the cytotoxicity of histones. Int J Mol Sci 19 (6): 1679, 1-10
Strubl, S.; Schubert, U; Kühnle, A.; Rebl, A.; Ahmadvand, N.; Fischer, S.; Preissner, K.; Galuska, S. P. (2018):
Polysialic acid is released by human umbilical vein endothelial cells (HUVEC) in vitro. Cell Biosci 8 (64):
Chen, S.; Palma Vera, S.; Langhammer, M.; Galuska, S. P.; Braun, B.C.; Krause, E.; Lucas-Hahn, A.; Schön, J. (2017):
An air-liquid interphase approach for modeling the early embryo-maternal contact zone. Sci Rep-UK 7: 42298, 1-7
Galuska, C.E.; Lütteke, T.; Galuska, S. P. (2017):
Is polysialylated NCAM not only a regulator during brain development but also during the formation of other organs?. Biology 6 (2): 27,1-15
Galuska, S. P.; Galuska, C.E.; Tharmalingam, T; Zlatina, K.; Prem, G.; Husejnov, F.C.O.; Rudd, P.M.; Vann, W.F.; Reid, C.; Vionnet, J.; Gallagher, M.E.; Carrington, F.A.; Hassett, S.L.; Carrington, S.D. (2017):
In vitro generation of polysialylated cervical mucins by bacterial polysialyltransferases to counteract cytotoxicity of extracellular histones. FEBS J 284 (11): 1688-1699
Chan, K.H.; Galuska, S. P.; Kudipudi, P.K.; Riaz, M.A.; Loveland, K.L.; Konrad, L. (2017):
Signaling by TGF-betas in tubule cultures of adult rat testis. Am J Transl Res 9 (3): 1173-1182
Galuska, C.E.; Dambon, J.; Kühnle, A.; Bornhöfft, K.; Prem, G.; Zlatina, K.; Lütteke, T.; Galuska, S. P. (2017):
Artificial polysialic acid chains as sialidase-resistant molecular-anchors to accumulate particles on neutrophil extracellular traps. Front Immunol 8: 1229, 1-10
Zlatina, K.; Lütteke, T.; Galuska, S. P. (2017):
Individual impact of distinct polysialic acid chain lengths on the cytotoxicity of histone H1, H2A, H2B, H3 und H4. POLYMERS-BASEL 9 (12): 720, 1-13
Kallolimath, S.; Castilho, A.; Strasser, R.; Grünwald-Gruber, C.; Altmann, F.; Strubl, S.; Galuska, C. E.; Zlatina, K.; Galuska, S. P.; Werner, S.; Thiesler, H.; Werneburg, S.; Hildebrandt, H.; Gerardy-Schahn, R.; Steinkellner, H. (2016):
Engineering of complex protein sialylation in plants. P Natl Acad Sci USA 113 (34): 9498-9503
Khosravi, F.; Michel, V.; Galuska, C. E.; Bhushan, S.; Christian, P.; Schuppe, H.C.; Pilatz, A.; Galuska, S. P.; Meinhardt, A. (2016):
Desialylation of spermatozoa and epithelial cell glycocalyx is a consequence of bacterial infection of the epididymis. J Biol Chem 291 (34): 17717-17726
Zhang, R.; Loers, G.; Schachner, M.; Boelens, R.; Wienk, H.; Siebert, S.; Eckert, T.; Kraan, S.; Rojas-Macias, M.; Lütteke, T.; Galuska, S. P.; Scheidig, A.; Petridis, A.; Liang, S.; Billeter, M.; Schauer, R.; Steinmeyer, J.; Schröder, J.J.; Siebert, H. (2016):
Molecular basis of the receptor interactions of polysialic acid (polySia), polySia mimetics, and sulfated polysaccharides. ChemMedChem 11 (9): 990-1002