Dr. agr. Winfried Otten

+49 38208 68-802
Leibniz Institute for Farm Animal Biology (FBN)
Institute of Behavioural Physiology
Psychophysiology Unit
Wilhelm-Stahl-Allee 2
18196 Dummerstorf

Research interests

    • Determination of glucocorticoids in hair and feathers as a biological indicator for retrospective minimally-invasive monitoring of animal welfare in different livestock species
    • Tryptophan metabolism: relevance for immune function, mood and behaviour
    • Analyses of neurotransmitters, catecholamines, their precursors and metabolites in biological samples using high performance liquid chromatography

      Curriculum Vitae

      • 1992-present: Scientist at the Leibniz Institute for Farm Animal Biology (FBN) Dummerstorf, Institute of Institute of Behavioural Physiology
      • 1993: Ph.D. at the Technical University of Munich
      • 1984-1989: Technical University of Munich, studies of agriculture with focus on animal production

      Teaching

      University of Rostock, Agricultural Sciences (Bachelor)
      Topics: stress, animal welfare

      Publications

      Heimbürge, S.; Kanitz, E.; Otten, W. (2019):
      The use of hair cortisol for the assessment of stress in animals. Gen Comp Endocr 270: 10-17
      Rauh, A.; Hofmann, Katharina; Harlizius, Jürgen; Weiss, Christine; Numberger, J.; Scholz, Tobias; Schulze-Borstel, T.; Otten, W.; Ritzmann, M.; Zöls, S. (2019):
      Schmerz- und Stressbestimmung bei der Injektion und Kastration von Saugferkeln unter Lokalanästhesie mit Procain und Lidocain: Teil 2: Abwehrverhalten, Katecholamine, koordinierte Bewegungsabläufe. TIERAERZTL PRAX 47 (3): 160-170
      Kanitz, E.; Tuchscherer, M.; Otten, W.; Tuchscherer, A.; Zebunke, M.; Puppe, B. (2019):
      Coping style of pigs is associated with different behavioral, neurobiological and immune reponses to stressful challenges. Front Behav Neurosci 13: 173, 1-15
      Lamp, O.; Reyer, H.; Otten, W.; Nürnberg, G.; Derno, M.; Wimmers, K.; Metges, C. C.; Kuhla, B. (2018):
      Intravenous lipid infusion affects dry matter intake, methane yield, and rumen bacteria structure in late-lactating Holstein cows. J Dairy Sci 101 (7): 6032-6046
      Wirthgen, E.; Otten, W.; Tuchscherer, M.; Tuchscherer, A.; Domanska, G.; Brenmoehl, J.; Günther, J.; Ohde, D.; Weitschies, W.; Seidlitz, A.; Scheuch, W.; Kanitz, E. (2018):
      Effects of 1-Methyltryptophan on immune responses and the kynurenine pathway after lipopolysaccharide challenge in pigs. Int J Mol Sci 19 (10): 3009, 1-23
      Kalbe, C.; Lösel, D.; Block, J.; Lefaucheur, L.; Brüssow, K.-P.; Bellmann, O.; Pfuhl, R.; Puppe, B.; Otten, W.; Metges, C. C.; Rehfeldt, C. (2017):
      Moderate high or low maternal protein diets change gene expression but not the phenotype of skeletal muscle from porcine fetuses. DOMEST ANIM ENDOCRIN 58: 63-75
      Stracke, J.; Otten, W.; Tuchscherer, A.; Puppe, B.; Düpjan, S. (2017):
      Serotonin depletion induces pessimistic-like behavior in a cognitive bias paradigm in pigs. Physiol Behav 174: 18-26
      Stracke, J.; Otten, W.; Tuchscherer, A.; Witthahn, M.; Metges, C. C.; Puppe, B.; Düpjan, S. (2017):
      Dietary tryptophan supplementation and affective state in pigs. J Vet Behav 20: 82-90
      Wirthgen, E.; Kunze, M.; Goumon, S.; Walz, C.; Höflich, C.; Spitschak, M.; Brenmoehl, J.; Kanitz, E.; Tuchscherer, M.; Otten, W.; Gimsa, U.; Schön, P.- C.; Manteuffel, C.; Tuchscherer, A.; Pfuhl, R.; Metges, C. C.; Stabenow, B.; Erdmann, S.; Schluricke, K.; Faucitano, L.; Hoeflich, A. (2017):
      Interference of stress with the somatotropic axis in pigs - lights on new biomarkers. Sci Rep-UK 7: 12055, 1-13
      Wirthgen, E.; Kanitz, E.; Tuchscherer, M.; Tuchscherer, A.; Domanska, G.; Weitschies, W.; Seidlitz, A.; Scheuch, E.; Otten, W. (2016):
      Pharmacokinetics of 1-methyl-L-tryptophan after single and repeated subcutaneous application in a porcine model. Exp Anim Tokyo 65 (2): 147-155
      Stracke, J.; Otten, W.; Tuchscherer, A.; Puppe, B.; Düpjan, S. (2016):
      Auswirkungen einer Tryptophansupplementierung auf das Verhalten in einem Cognitive-bias-Paradigma beim Hausschwein. In: Aktuelle Arbeiten zur artgemäßen Tierhaltung 2016 (KTBL-Schrift , 511) KTBL, Darmstadt (978-3-945088-25-8 ): 236-246
      Otten, W.; Kanitz, E.; Tuchscherer, M. (2015):
      The impact of pre-natal stress on offspring development in pigs. J Agr Sci 153 (5): 907-919
      Metges, C. C.; Görs, S.; Martens, K.; Krüger, R.; Metzler-Zebeli, B.; Nebendahl, C.; Otten, W.; Kanitz, E.; Zeyner, A.; Hammon, H. M.; Pfuhl, R.; Nürnberg, G. (2015):
      Body composition and plasma lipid and stress hormone levels during 3 weeks of feed restriction and refeeding in low birth weight female pigs. J Anim Sci 93 (3): 999-1014
      Gruse, J.; Görs, S.; Otten, W.; Weitzel, J. M.; Wolffram, S.; Metges, C. C.; Hammon, H. M. (2015):
      Effects of oral quercetin supplementation on glucose metabolism in newborn dairy calves fed colostrum or a milk-based formula. Schriftenreihe / Leibniz-Institut für Nutztierbiol 23: 5-8
      Lamp, O.; Derno, M.; Otten, W.; Mielenz, M.; Nürnberg, G.; Kuhla, B. (2015):
      Metabolic heat stress adaption in transition cows: differences in macronutrient oxidation between late-gestating and early-lactating German Holstein dairy cows. Plos One 10 (5): e0125264, 1-24
      Stoldt, A.-K.; Derno, M.; Nürnberg, G.; Weitzel, J. M.; Otten, W.; Starke, A.; Wolffram, S.; Metges, C. C. (2015):
      Effects of a 6-wk intraduodenal supplementation with quercetin on energy metabolism and indicators of liver damage in periparturient dairy cows. J Dairy Sci 98 (7): 4509-4520
      Übel, N.; Zöls, S.; Otten, W.; Sauter-Louis, C.; Heinritzi, K.; Ritzmann, M.; Eddicks, M. (2015):
      Auswirkungen der zeitgleichen Durchführung zootechnischer Eingriffe an Saugferkeln. TIERAERZTL PRAX 43 (6): 359-366
      Gruse, J.; Görs, S.; Tuchscherer, A.; Otten, W.; Weitzel, J. M.; Metges, C. C.; Wolffram, S.; Hammon, H. M. (2015):
      The effects of oral quercetin supplementation on splanchnic glucose metabolism in 1-week-old calves depend on diet after birth. J Nutr 145 (11): 2486-2495
      Wirthgen, E.; Tuchscherer, M.; Otten, W.; Domanska, G.; Wollenhaupt, K.; Tuchscherer, A.; Kanitz, E. (2014):
      Activation of indoleamine 2,3-dioxygenase by LPS in a porcine model. Innate Immun-London 20 (1): 30-39
      Metges, C. C.; Görs, S.; Lang, I. S.; Hammon, H. M.; Brüssow, K.-P.; Weitzel, J. M.; Nürnberg, G.; Rehfeldt, C.; Otten, W. (2014):
      Low and high dietary protein: carbohydrate ratios during pregnancy affect materno-fetal glucose metabolism in pigs. J Nutr 144 (2): 155-163