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Leiter:  
Prof. Dr. Klaus Wimmers  

Tel.: +49 38208 68-700  
Fax: +49 38208 68-702  
Email wimmers@fbn-dummerstorf.de  
 
Sekretariat:  
Tel.: +49 38208 68-701  

 

2010

  • Brand, B.; Baes, C.; Mayer, M.; Reinsch, N.; Seidenspinner, T.; Thaller, G.; Kühn, Ch., (2010), Quantitative trait loci mapping of calving and conformation traits on Bos taurus autosome 18 in the German Holstein population . J Dairy Sci 93 (3): 1205-1215
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  • Eberlein, A.; Kalbe, C.; Goldammer, T.; Brunner, R.; Kühn, Ch.; Weikard, R., (2010), Analysis of struture and gene expression of bovine CCDC3 gene indicates a function in fat metabolism. Comp Biochem Phys B 156: 19-25
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  • Fürbaß, R.; Tomek, W.; Vanselow, J., (2010), Upstream Stimulating Factors 1 and 2 Enhance Transcription from the Placenta-Specific Promoter 1.1 of the Bovine Cyp19 Gene. BMC Mol Biol 11: 5
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  • Maak, S.; Boettcher, D.; Komolka, K.; Tetens, J.; Wimmers, K.; Reinsch, N.; Swalve, H.; Thaller, G., (2010), Exclusion of sequence polymorphisms in the porcine ITGA5 and MIR148B loci as causal variation for congenital splay leg in piglets. Anim Genet (doi: 10.1111/j.1365-2052.2010.02047.x)
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  • Maak, S.; Boettcher, D.; Komolka, K.; Tetens, J.; Wimmers, K.; Reinsch, N.; Swalve, H.; Thaller, G., (2010), Exclusion of sequence polymorphisms in the porcine ITGA5 and MIR148B loci as causal variation for congenital splay leg in piglets. Anim Genet 41 (4): 447-448
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  • Sipka, A.; Langner, K.; Seyfert, H.-M.; Schuberth, H.-J., (2010), Substance P alters the in vitro LPS responsiveness of bovine monocytes and blood-derived macrophages. VET IMMUNOL IMMUNOP (doi:10.1016/j.vetimm.2010.03.011)
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  • Srikanchai, T.; Muràni, E.; Phatsara, C.; Schwerin, M.; Schellander, K.; Ponsuksili, S.; Wimmers, K., (2010), Association of ZYX polymorphisms with carcass and meat quality traits in commercial pigs. Meat Sci 84 (1): 159-164
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2009

  • Amaral, M.E.J.; Riggs, K.; Goldammer, T.; Weikard, R.; Brunner, R.; Stafuzza, N.; Moore, S.; Womack, J.E., (2009), A first generation whole genome RH map of the river buffalo with comparison to domestic cattle.. BMC Genomics
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  • Baes, C.; Brand, B.; Mayer, M.; Kühn, Ch.; Liu, Z.; Reinhardt, F.; Reinsch, N., (2009), Refined positioning of a quantitative trait locus affecting somatic cell score on chromosome 18 in the German Holstein using linkage disequilibrium . J Dairy Sci 92 (8): 4046-4054
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  • Brand, B.; Baes, C.; Mayer, M.; Reinsch, N.; Kühn, Ch., (2009), Identification of a haplotype on Bos taurus chromosome 18 affecting somatic cell score in German Holstein cattle. BMC Genet 50: 50
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  • Buitkamp, J.; Kühn, Ch.; Semmer, J.; Götz, K.W., (2009), Assignment of the locus for arachnomelia syndrome to bovine chromosome 23 in Simmental cattle. Anim Genet 40: 894-899
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  • Duske, K.; Hammon, H.; Langhof, A.K.; Bellmann, O.; Losand, B.; Nürnberg, K.; Nürnberg, G.; Sauerwein, H.; Seyfert, H.-M.; Metges, C. C., (2009), Metabolism and lactation performance in dairy cows fed a diet containing rumen-protected fat during the last twelve weeks of gestation. . J Dairy Sci 92: 1670-1684
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  • Eberlein, A.; Takasuga, A.; Setoguchi, K.; Pfuhl, R.; Flisikowski, K.; Fries, R.; Klopp, N.; Weikard, R.; Kühn, Ch., (2009), Dissection of genetic factors modulating fetal growth in cattle indicates a substantial role of the non-SMC condensin I complex, subunit G (NCAPG) gene. Genetics 183: 951-964
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  • Elsik, C.G.; Tellam, R.; Worley, K.; Eberlein, A.; Weikard, R.; Bovine Genome Sequencing-Analysis, C., (2009), The genome sequence of taurine cattle: A window to ruminat biology and evolution. Science 324 (5926): 522-528
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  • Goldammer, T.; Brunner, R.; Rebl, A.; Wu, Ch.; Nomura, K.; Gill, Clare A.; Hadfield, T.S.; Dalrymple, B.; Womack, J.E.; Cockett, N., (2009), A high-resolution radiation hybrid map of sheep chromosome X and comparison with human and cattle.. Cytogenet Genome Res 125 (1): 40-45
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  • Goldammer, T.; Brunner, R.; Rebl, A.; Wu, Ch.; Nomura, K.; Hadfield, T.S.; Maddox, J.F.; Cockett, N., (2009), Cytogenetic anchoring of radiation hybrid and virtual maps of sheep chromosome X and comparison of X chromosomes in sheep, cattle, and human.. Chromosome Res 17 (4): 497-506
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  • Goldammer, T.; Di Meo, G.; Lühken, G.; Droegemuller, C.; Wu, Ch.; Kijas, J.W.; Dalrymple, B.; Nicolas, F.; Maddox, J.F.; Iannuzzi, L; Cockett, N., (2009), Molecular Cytogenetics and Gene Mapping in Sheep (Ovis aries, 2n = 54). Cytogenet Genome Res 126 (1-2): 63-76
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  • Goldammer, T.; Kühn, Ch.; Brunner, R.; Weikard, R., (2009), Evolutionary break point analysis between the proximal half of bovine chromosome 27 and conserved segments of the human genome.. Cytogenet Genome Res 125 (1): 33-39
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  • Goldammer, T.; Schmidt, P.; Weikard, R., (2009), Cytogenetic and syntenic assignment of the bovine platelet-activating factor receptor (PTAFR) to cattle chromosome 2 . Arch Tierzucht 52 (4): 448-450
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  • Griesbeck-Zilch, B.; Osman, M.; Kühn, Ch.; Schwerin, M.; Bruckmaier, R.; Pfaffl, M.; Hammerle-Fickinger, A.; Meyer, H.H.D; Wellnitz, O., (2009), Analysis of key molecules of the innate immune system in mammary epithelial cells isolated from marker-assisted and conventionally selected cattle. J Dairy Sci 93 (9): 4621-4633
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  • Günther, J.; Koczan, D.; Yang, W.; Nürnberg, G.; Repsilber, D.; Schuberth, H.-J.; Zaneta, P.; Molenaar, A.; Seyfert, H.-M., (2009), Assessment of the immune capacity of mammary epithelial cells: Comparison of mammary tissue after challenge with Eschrichia coli.. Vet Res 40 (4): 31
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  • Günther, J.; Lui, S.; Esch, K.; Schuberth, H.-J.; Seyfert, H.-M., (2009), Stimulated expression of TNF-alpha and IL-8, but not of Lingual antimicrobila peptide reflects the concentration of pathogens contacting bovine Mammary Epithelial Cells. VET IMMUNOL IMMUNOP (doi:10.1016/j.vetimm.2009.11.004)
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  • Löhrke, B.; Xu, J.; Weitzel, J.; Krüger, B.; Goldammer, T.; Viegutz, T., (2009), N-acetylcysteine impairs survival of luteal cells through mitochondrial dysfunction.. Cytom Part A 77 A (4): 310-320
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  • Maak, S.; Boettcher, D.; Tetens, J.; Swalve, H.; Wimmers, K.; Thaller, G., (2009), Expression of microRNAs is not related to increased expression of ZDHHC9 in hind leg muscles of splay leg piglets. Mol Cell Probe (doi: 10.1016/j.mcp.2009.09.001)
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  • Maak, S.; Boettcher, D.; Tetens, J.; Wensch-Dorendorf, M.; Nürnberg, G.; Wimmers, K.; Swalve, H.; Thaller, G., (2009), Identification of candidate genes for congenital splay leg in piglets by alternative analysis of DNA microarray data. Int J Biol Sci
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  • Metges, C. C.; Peters, M.; Sauerwein, H.; Ooster, A.; Ponsuksili, S.; Altmann, S.; Oster, M.; Rehfeldt, C.; Wimmers, K., (2009), Fetal Programming: Mütterliche Ernährung und Merkmalsausprägung der Nachkommen beim Schwein. Genomexpress (1.09): 11-13
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  • Muràni, E.; Ponsuksili, S.; Seyfert, H.-M.; Shi, X.; Wimmers, K., (2009), Dual effect of a single nucleotide polymorphism in the first intron of the porcine Secreted phosphoprotein 1 gene: allele-specific binding of C/EBP beta and activation of aberrant splicing.. BMC Mol Biol 10 (96): 1-11
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  • Muràni, E.; Ponsuksili, S.; Srikanchai, T.; Maak, S.; Wimmers, K., (2009), Expression of the porcine adrenergic receptor beta 2 gene in longissimus dorsi muscle is affected by cis-regulatory DNA variation. Anim Genet 40 (1): 80-89
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  • Nimz, M.; Spitschak, M.; Schneider, F.; Fürbaß, R.; Vanselow, J., (2009), Down-regulation of genes encoding steroidogenic enzymes and hormone receptors in late preovulatory follicles of the cow coincides with an accumulation of intrafollicular steroids. DOMEST ANIM ENDOCRIN 37: 45-54
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  • Perucatti, A.; Di Meo, G.; Goldammer, T.; Incarnato, D.; Nicolae, I; Brunner, R.; Iannuzzi, L, (2009), FISH-mapping comparison between river buffalo chromosome 7 and sheep chromosome 6: assignment of new loci and comparison with HSA4.. Cytogenet Genome Res 124 (1): 106-111
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  • Ponsuksili, S.; Muràni, E.; Phatsara, C.; Schwerin, M.; Schellander, K.; Wimmers, K., (2009), Porcine muscle sensory attributes associate with major changes in gene networks invoving CAPZB, ANKDR1, and CTBP2. Funct Integr Genomic 9 (4): 455-471
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  • Rebl, A.; Anders, E.; Wimmers, K.; Goldammer, T., (2009), Cloning and tissue-specific expression of a delta-COP homologue in a freshwater and a brackish water-adapted strain of rainbow trout (Oncorhynchus mykiss). Genes Genet Syst 84 (3): 239-243
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  • Rebl, A.; Fischer, K.; Köllner, Bernd; Seyfert, H.-M., (2009), Characterization of two key-factors of teleost Innate Immunity: MyD88 and Serum Amyloid A from rainbow trout.. VET IMMUNOL IMMUNOP 131: 122-126
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  • Rebl, A.; Goldammer, T.; Fischer, K.; Köllner, Bernd; Seyfert, H.-M., (2009), Characterization of two key molecules of teleost innate immunity from rainbow trout (Oncorhynchus mykiss): MyD88 and SAA. VET IMMUNOL IMMUNOP (doi:10.1016/http://dx.doi.org/10.1016/j.vetimm.2009.03.006)
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  • Rebl, A.; Goldammer, T.; Seyfert, H.-M., (2009), Toll-like receptor signaling in bony fish.. VET IMMUNOL IMMUNOP (doi:10.1016/j.vetimm.2009.09.021)
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  • Rebl, A.; Köllner, Bernd; Anders, E.; Wimmers, K.; Goldammer, T., (2009), Peptidylarginine deiminase gene is differentially expressed in freshwater and brackish water rainbow trout.. Mol Biol Rep (aug-20)
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  • Rief, A.; Schwerin, M.; Goldammer, T., (2009), Cytogenetic and radiation hybrid mapping of the bovine interleukin 4 induced 1 (IL4I1) gene to cattle chromosome 18.. Arch Tierzucht 52 (3): 340-342
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  • Srikanchai, T.; Muràni, E.; Wimmers, K.; Ponsuksili, S., (2009), Four loci differentially expressed in muscle tissue depending on water-holding capacity are associated with meat quality in commercial pig herds . Mol Biol Rep 37 (1): 595-601
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  • Taylor, U.; Zerbe, H.; Seyfert, H.-M.; Rath, D.; Baulain, U.; Langner, Ch.; Schuberth, H.-J., (2009), Porcine spermatozoa inhibit post-breeding cytokine induction in uterine epithelial cells in vivo.. Anim Reprod Sci 115: 279-289
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  • Tetzlaff, S.; Chomdej, S.; Jonas, E; Ponsuksili, S.; Muràni, E.; Phatsara, C.; Schellander, K.; Wimmers, K., (2009), Association of parathyroid hormone-like hormone (PTHLH) and its receptor (PTHR1) with the number of functional and inverted teats in pigs. . J Anim Breed Genet 126: 237-241
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  • Tetzlaff, S.; Jonas, E; Phatsara, C.; Muràni, E.; Ponsuksili, S.; Schellander, K.; Wimmers, K., (2009), Evidence for association of lymphoid enhancer-binding factor-1 (LEF1) with the number of functional and inverted teats in pigs. . Cytogenet Genome Res 124 (2): 139-146
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  • Tetzlaff, S.; Muràni, E.; Schellander, K.; Ponsuksili, S.; Wimmers, K., (2009), Differential expression of growth factors and their receptors points out their involvement in the inverted teat defect in pigs. J Anim Sci (31.07.2009)
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  • Tiemann, U.; Tomek, W.; Schneider, F.; Müller, M.; Pöhland, R.; Vanselow, J., (2009), The mycotoxins alternariol and alternariol methyl ether negatively affect progesterone synthesis in porcine granulosa cells in vitro. Toxicol lett 186: 139-145
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  • Vanselow, J.; Spitschak, M.; Nimz, M.; Fürbaß, R., (2009), DNA Methylation Is Not Involved in Preovulatory Down-Regulation of CYP11A1, HSD3B1, and CYP19A1 in Bovine Follicles But May Play a Role for Permanent Silencing of CYP19A1 in Large Granulosa Lutein Cells. Biol Reprod (10.1095/biolreprod.109.079251 [d
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  • Verma, S.; Goldammer, T.; Aitken, R., (2009), Characterization of bovine activation-induced cytidine deaminase . VET IMMUNOL IMMUNOP 128 (1-3): 307
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  • Weikard, R.; Goldammer, T.; Eberlein, A.; Kühn, Ch., (2009), Novel transcripts discoveredby mining grnomic DNA from defined regions of bovine chromosome 6. BMC Genomics 10: 186
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  • Wimmers, K.; Muràni, E.; Schellander, K.; Ponsuksili, S., (2009), QTL for traits related to humoral immune response estimated from data of a porcine F2 resource population. INT J IMMUNOGENET 36 (3): 141-151
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  • Wu, Ch.; Nomura, K.; Goldammer, T.; Hadfield, T.S.; Dalrymple, B.; McWilliam, S; Maddox, J.F.; Cockett, N., (2009), A radiation hybrid comparative map of ovine chromosome 1 aligned to the virtual sheep genome.. Anim Genet 40 (4): 435-455
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2008

  • Droegemuller, M.; Tetens, J.; Dalrymple, B.; Goldammer, T.; Wu, Ch.; Cockett, N.; Leeb, T.; Droegemuller, C., (2008), A comparative radiation hybrid map of sheep chromosome 10.. Cytogenet Genome Res 121 (1): 35-40
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  • Fürbaß, R.; Selimyan, R.; Vanselow, J., (2008), DNA methylation and chromatin accessibility of the proximal Cyp19 promoter region 1.5/2 correlate with expression levels in sheep placentomes. Mol Reprod Dev 75 (1): 1-7
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  • Griesbeck-Zilch, B.; Meyer, H.H.D; Kühn, Ch.; Schwerin, M.; Wellnitz, O., (2008), Staphylococcus aureus and Escherichia coli cause deviating expression profiles of cytokines and lactoferrin messenger ribonucleic acid in mammary epithelial cells. J Dairy Sci 91: 2215-2224
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  • Jonas, E; Schreinemachers, H.-J.; Kleinwächter, T.; Ün, G.; Oltmanns, I.; Tetzlaff, S.; Jennen, D.; Tesfaye, D.; Ponsuksili, S.; Muràni, E.; Jüngst, H.; Tholen, E.; Schellander, K.; Wimmers, K., (2008), QTL for the heritable inverted teat defect in pigs. Mamm Genome 19: 127-138
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  • Kanitz, W.; Brüssow, K.-P.; Bugislaus, A.; Kühn, Ch.; Matthes, Winfried; Wangler, A., (2008), Verbesserung funktionaler Merkmale: Eine Herausforderung zur vertieften Phänotypisierung. Arch Tierzucht 51 (Sonderheft 1): 83-97
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  • Kühn, Ch., (2008), Verbesserung der Eutergesundheit durch Zucht?. Zuchtungskunde 81: 1-7
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  • Kühn, Ch.; Reinhardt, F.; Schwerin, M., (2008), Marker assisted selection of heifers improved milk somatic cell count compared to selection on conventional pedigree breeding values. Arch Tierzucht 51 (1): 23-32
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  • Liu, G; Kim, JJ; Jonas, E; Wimmers, K.; Ponsuksili, S.; Muràni, E.; Phatsara, C.; Tholen, E.; Jüngst, H.; Tesfaye, D.; Ji Lan Chen, J.L; Schellander, K., (2008), Combined line-cross and half-sib QTL analysis in Duroc-Pietrain population. Mamm Genome 19: 429-438
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  • Muràni, E.; Ponsuksili, S.; Srikanchai, T.; Maak, S.; Wimmers, K., (2008), Expression of the porcine adrenergic receptor beta 2 gene in longissimus dorsi muscle is affected by cis-regulatory DNA variation. Anim Genet 40: 80-89
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  • Petzl, W.; Zerbe, H.; Günther, J.; Yang, W.; Seyfert, H.-M.; Nürnberg, G.; Schuberth, H.-J., (2008), Escherichia coli, but not Staphylococcus aureus triggers an early increased expression of factors contributing to the innate immune defense in the udder of the cow.. Vet Res (DOI : 10.1051/vetres:2007057)
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  • Phatsara, C.; Jonas, E; Yammuen-art, S; Buschbell, K; Tesfaye, D.; Ponsuksili, S.; Tholen, E.; Jüngst, H.; Schellander, K.; Wimmers, K., (2008), Physiological interactions between the endocrine and immune systems shown in gene analysis in pigs. Developments in Biologicals 132: 161-167
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  • Ponsuksili, S.; Jonas, E; Muràni, E.; Phatsara, C.; Srikanchai, T.; Walz, C.; Schwerin, M.; Schellander, K.; Wimmers, K., (2008), Trait correlated expression combined with expression QTL analysis reveals biological pathways and candidate genes affecting water holding capacity of muscle. BMC Genomics 9: 367
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  • Ponsuksili, S.; Muràni, E.; Phatsara, C.; Jonas, E; Walz, C.; Schwerin, M.; Schellander, K.; Wimmers, K., (2008), Expression profiling of muscle reveals transcripts differentially expressed in muscle that affect water-holding capacity of pork. J Agr Food Chem 56: 10311-10317
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  • Ponsuksili, S.; Muràni, E.; Wimmers, K., (2008), Porcine genome-wide gene expression in response to tetanus toxoid vaccine. Developments in Biologicals 132: 185-195
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  • Rebl, A.; Anders, E.; Wimmers, K.; Goldammer, T., (2008), Characterization of Dehydrodolichyl diphosphate synthase gene in rainbow trout (Oncorhynchus mykiss).. Comp Biochem Biophys B (2008 Dec 10)
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  • Rebl, A.; Hoyheim, B.; Fischer, K.; Köllner, Bernd; Siegl, Edda; Seyfert, H.-M., (2008), Tollip, a negative regulator of TLR-signalling, is encoded by twin genes in salmonid fish. . Fish Shellfish Immun 25: 153-162
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  • Seyfert, H.-M., (2008), Bovine TLR2 and TLR4 properly transduce signals from S. aureus and E. coli, but S. aureus fails to both activate NF-kappaB in Mammary Epithelial Cells and to quickly induce TNF-alpha and Interleukin-8 (CXCL8) expression in the udder. MOL IMMUNOL (doi:10.1
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  • Tiemann, U.; Brüssow, K.-P.; Dänicke, S.; Vanselow, J., (2008), Feeding of pregnant sows with mycotoxin-contaminated diets and their non-effect on foetal and maternal transcription genes of the insulin-growth factor system.. Food Addit Contam 18: 1-9
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  • Vanselow, J.; Fürbaß, R.; Tiemann, U., (2008), Cultured bovine trophoblast cells differentially express genes encoding key steroid synthesis enzymes. Placenta 29: 531-538
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  • Vanselow, J.; Nürnberg, G.; Koczan, D.; Langhammer, M.; Thiesen, H.-J.; Reinsch, N., (2008), Expression profiling of a high-fertility mouse line by microarray analysis and qPCR. BMC Genomics 9 (1): 307
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  • Vanselow, J.; Selimyan, R.; Fürbaß, R., (2008), DNA methylation of placenta-specific Cyp19 promoters of cattle and sheep. Exp Clin Endocr Diab 116: 437-442
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  • Wimmers, K., (2008), 14. Mitteldeutscher Schwein-Workshop, Kurzfassungen, Fruchtbarkeit im Sauenbestand; 16.5.-17.5.08, Bernbur 14. Mitteldeutscher Schwein-Workshop, Wissenschaftliche Beiträge, Fruchtbarkeit im Sauenbestand; 16.5.-17.5.08, Bernburg; Seiten 111-12. In: Stan
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  • Wimmers, K.; Jonas, E; Schreinemachers, H.-J.; Tesfaye, D.; Ponsuksili, S.; Tholen, E.; Jüngst, H.; Schellander, K.; Phatsara, C., (2008), Verification of chromosomal regions affecting the innate immunity in pigs using linkage mapping.. Developments in Biologicals 132: 279-286
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  • Wimmers, K.; Kumar, K.G.; Schellander, K.; Ponsuksili, S., (2008), Porcine IL12A and IL12B gene mapping, variation and evidence of association with lytic complement and blood leucocyte proliferation traits. INT J IMMUNOGENET 35: 75-85
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  • Wimmers, K.; Ngu, N.T.; Jennen, D.; Tesfaye, D.; Muràni, E.; Schellander, K.; Ponsuksili, S., (2008), Relationship between myosin heavy chain isoform expression and muscling in several diverse pig breeds. J Anim Sci 86: 795-803
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  • Wu, Ch.; Nomura, K.; Goldammer, T.; Hadfield, T.S.; Dalrymple, B.; McWilliam, S.; Maddox, J.F.; Womack, J.E.; Cockett, N., (2008), A high-resolution comparative radiation hybrid map of ovine chromosomal regions that are homologous to human chromosome 6 (HSA6). . Anim Genet 39 (5): 459-467
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